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  Obesity and kidney disease in type 1 and 2 diabetes: an analysis of the National Diabetes Audit
  This study has highlighted a strong association between obesity and kidney disease in type 1 diabetes and confirmed their association in type 2 diabetes (QJM)
   
  Influence of macro- and microvascular comorbidity on time to insulin initiation in type 2 diabetes patients: A retrospective database analysis in Germany, France, and UK
  A more rapid progression to insulin therapy was found in patients with microvascular complications (Primary Care Diabetes)
   
  Retinal Layers Changes in Human Preclinical and Early Clinical Diabetic Retinopathy Support Early Retinal Neuronal and Müller Cells Alterations
  Neuronal loss is accompanied (or induced) by Müller cells activation, with increasing thickness in the INL. Automatic intraretinal layering by spectral-domain optical coherence tomography may be a useful tool to diagnose and monitor early intraretinal changes in diabetic retinopathy (Journal of Diabetes Research)
   
  The Effect of Diabetes-Associated Autoantigens on Cell Processes in Human PBMCs and Their Relevance to Autoimmune Diabetes Development
  These important immune response-related processes largely included the induction of Th17 and Th22 responses, as well as cytoskeletal rearrangements, MHCII presentation, and the upregulation of CD4, TGF-beta, and STAT3. These findings potentially suggest that these processes could be utilised as predictive markers for the development of T1D or as molecular targets for the repression of specific immunocompetent cell populations for the treatment of diabetes (Journal of Diabetes Research)
   
  The Diabetes ‘Breathalyzer’
  Pitt chemists demonstrate sensor technology that could detect and monitor diabetes through breath analysis alone (University of Pittsburgh)
   
  Carotid ultrasonography: A potent tool for better clinical practice in diagnosis of atherosclerosis in diabetic patients
  It is expected that carotid ultrasonography will become a potent tool for better clinical practice of atherosclerosis in diabetic patients (Journal of Diabetes Investigation)
   
  Relationship between type-2 diabetes and use of metformin with risk of colorectal adenoma in an American population receiving colonoscopy
  Within diabetic patient group, people who were taking metformin have significantly lower risk of colorectal adenoma. Diabetic subjects have increased risk of developing colorectal adenoma. Our study also supports the beneficial effect of metformin in development of colorectal adenoma (Diabetes and Its Complications)
   
  Insulin Resistance and Risk of Incident Heart Failure
  Fasting insulin was positively associated with adverse echocardiographic features and risk of subsequent HF in Cardiovascular Health Study participants, including those without an antecedent myocardial infarction (Circulation: Heart Failure)
   
  Outcome of review of new safety data on insulin glargine
  Data from population-based studies and the scientific literature do not indicate an increased risk of cancer (European Medicines Agency)
   
  Readjudication of the Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycemia in Diabetes Trial (RECORD)
  Joint Meeting of the Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee (Food and Drug Administration)
   
  Diamyd expands its Scientific Advisory Board
  Diamyd Medical recently acquired exclusive rights relating to the therapeutic use of GABA for the treatment of diabetes and other inflammation-related conditions (Diamyd Medical)
   

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