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Obesity
and kidney disease in type 1 and 2 diabetes: an analysis
of the National Diabetes Audit |
| |
This study has highlighted a
strong association between obesity and kidney disease in
type 1 diabetes and confirmed their association in type
2 diabetes (QJM) |
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|
|
Influence
of macro- and microvascular comorbidity on time to insulin
initiation in type 2 diabetes patients: A retrospective
database analysis in Germany, France, and UK |
| |
A more rapid progression to
insulin therapy was found in patients with microvascular
complications (Primary Care Diabetes) |
| |
|
|
Retinal
Layers Changes in Human Preclinical and Early Clinical
Diabetic Retinopathy Support Early Retinal Neuronal and
Müller Cells Alterations |
| |
Neuronal loss is accompanied
(or induced) by Müller cells activation, with increasing thickness in the INL. Automatic intraretinal
layering by spectral-domain optical coherence tomography
may be a useful tool to diagnose and monitor early intraretinal
changes in diabetic retinopathy (Journal of Diabetes Research) |
| |
|
|
The
Effect of Diabetes-Associated Autoantigens on Cell Processes
in Human PBMCs and Their Relevance to Autoimmune Diabetes
Development |
| |
These important immune response-related
processes largely included the induction of Th17 and Th22
responses, as well as cytoskeletal rearrangements, MHCII
presentation, and the upregulation of CD4, TGF-beta, and
STAT3. These findings potentially suggest that these processes
could be utilised as predictive markers for the development
of T1D or as molecular targets for the repression of specific
immunocompetent cell populations for the treatment of diabetes
(Journal of Diabetes Research) |
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|
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The
Diabetes ‘Breathalyzer’ |
| |
Pitt chemists demonstrate sensor
technology that could detect and monitor diabetes through
breath analysis alone (University of Pittsburgh) |
| |
|
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Carotid
ultrasonography: A potent tool for better clinical practice
in diagnosis of atherosclerosis in diabetic patients |
| |
It is expected that carotid
ultrasonography will become a potent tool for better clinical
practice of atherosclerosis in diabetic patients (Journal
of Diabetes Investigation) |
| |
|
|
Relationship
between type-2 diabetes and use of metformin with risk
of colorectal adenoma in an American population receiving
colonoscopy |
| |
Within diabetic patient group,
people who were taking metformin have significantly lower
risk of colorectal adenoma. Diabetic subjects have increased
risk of developing colorectal adenoma. Our study also supports
the beneficial effect of metformin in development of colorectal
adenoma (Diabetes and Its Complications) |
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|
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Insulin
Resistance and Risk of Incident Heart Failure |
| |
Fasting insulin was positively
associated with adverse echocardiographic features and
risk of subsequent HF in Cardiovascular Health Study participants,
including those without an antecedent myocardial infarction
(Circulation: Heart Failure) |
| |
|
|
Outcome
of review of new safety data on insulin glargine |
| |
Data from population-based studies
and the scientific literature do not indicate an increased
risk of cancer (European Medicines Agency) |
| |
|
|
Readjudication
of the Rosiglitazone Evaluated for Cardiovascular Outcomes
and Regulation of Glycemia in Diabetes Trial (RECORD) |
| |
Joint Meeting of the Endocrinologic
and Metabolic Drugs Advisory Committee and the Drug Safety
and Risk Management Advisory Committee (Food and Drug Administration) |
| |
|
|
Diamyd
expands its Scientific Advisory Board |
| |
Diamyd Medical recently acquired
exclusive rights relating to the therapeutic use of GABA
for the treatment of diabetes and other inflammation-related
conditions (Diamyd Medical) |
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