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Secular
decline in mortality from coronary heart disease in adults with
diabetes mellitus: cohort study |
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The strong general reduction in mortality rates
from coronary heart disease from the first to the second follow-up
period also benefited people with diabetes, but the more than twofold
higher mortality from coronary heart disease associated with diabetes
persisted over time (BMJ, UK) |
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|
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Monogenic
Diabetes – first in a new series of NDST Diabetes Bulletin |
| |
The National Diabetes Support Team have published
the first in the new series of “Diabetes Bulletin”. The Bulletin is a one page digest on a topic of the moment intended for all
busy healthcare professionals who want a quick and comprehensive
update on an important area (NDST, UK) |
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|
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A
profile of impaired insulin degradation in relation to late-life
cognitive decline: A preliminary investigation |
| |
These preliminary analyses of a possible phenotype
of impaired insulin degradation provide supportive evidence that
deficits in insulin degradation may be related to late-life verbal
memory decline (Geriatric Psychiatry) |
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|
|
Metformin
as first choice in oral diabetes treatment: the UKPDS experience |
| |
The UK Prospective Diabetes Study (UKPDS) demonstrated
a substantial beneficial effect of metformin therapy on cardiovascular
disease (CVD) outcomes, with a 36% relative risk reduction in all
cause mortality and a 39% relative risk reduction in myocardial
infarction (PubMed, USA) |
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|
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Biphasic
insulin aspart 30 treatment improves glycaemic control in patients
with type 2 diabetes |
| |
The use of BIAsp 30 monotherapy or in combination
with OADs in clinical practice was effective and safe in patients
with poorly controlled type 2 diabetes mellitus (PubMed, USA) |
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|
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The
role of macrophage migration inhibitory factor on glucose metabolism
and diabetes |
| |
Macrophage migration inhibitory factor (MIF)
is a proinflammatory cytokine involved in many inflammatory reactions
and disorders, and it has become evident that it also affects glucose
homeostasis. The protein is produced by pancreatic beta cells and
can promote the release of insulin (Diabetologia) |
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|
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Do
Internists, Pediatricians, and Psychiatrists Feel Competent in
Obesity Care? |
| |
This survey demonstrated a critical need for
training in specific areas of obesity care. The proposed curriculum
targets these areas taking into consideration observed differences
across specialties (Journal of General Internal Medicine, USA) |
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|
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Impact
of statins on modulation by insulin of expression of plasminogen
activator inhibitor type-1 |
| |
Insulin-mediated augmented expression of PAI-1
may be amenable to suppression attributable to pleiotropic effects
of statins, potentially diminishing cardiovascular risk in patients
with insulin resistance (Coronary Artery Disease, USA) |
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|
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A
retrospective evaluation of congestive heart failure and myocardial
ischemia events in patients with type 2 diabetes mellitus |
| |
CHF incidence may be greater when rosiglitazone
is combined with sulfonylureas or insulin. When data were pooled,
more events of myocardial ischemia were observed with rosiglitazone
versus control. Final results from RECORD will allow a more rigorous
evaluation of the cardiovascular safety profile (PubMed, USA) |
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|
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Diabetes
Awareness Week begins |
| |
Diabetes Australia launches its major Diabetes
Awareness Week campaign today, with the message of urging all Australians
to be aware of their family history of type 2 diabetes (Diabetes,
Australia) |
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|
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Swimmer
takes on the Northumberland Strait |
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Adding to her challenge is the fact that she
has Type 1 diabetes. She wears a waterproof insulin pump while
swimming and has to stop every half-hour, treading water while
she checks her blood sugar levels (Globe and Mail, Canada) |
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