Innate and adaptive immune gene expression profiles as biomarkers in human type 1 diabetes

Analyses of regulatory gene expression ratios revealed a dynamic disproportion of CTLA4 versus CD3G expression in samples from at-risk, new-onset and long-term T1D patients. These changes could serve as immunological biomarkers for the status of the immune system during T1D progression and therapeutic interventions (Clinical and Experimental Immunology)