Insulin analogues have been getting a bad press over the past 12 months and the latest revamp of NICE guidelines is expected to outlaw their routine use in type 2 diabetes. This follows a Channel 4 News investigation and subsequent publication in ‘BMJ’ http://bmjopen.bmj.com/content/1/2/e000258.full suggesting savings of more than half a billion GBP over the last 10 years if only human insulin had been prescribed. So why have insulin manufacturers found their position so hard to defend?

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