Chronic Kidney Disease, Insulin Resistance, and Incident Diabetes in Older Adults
Among older adults, lower eGFR was associated with insulin resistance. However, with lower eGFR, ß cell function was appropriately augmented and risks of impaired glucose tolerance and incident diabetes were not increased (Clinical journal of the American Society of Nephrology)
Changes in Treatment Adherence and Glycemic Control During the Transition to Adolescence in Type 1 Diabetes
The magnitude of the effect of declining treatment adherence (blood glucose monitoring frequency – BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence (Diabetes Care)
Altered Excitation-inhibition Balance in the Brain of Patients with Diabetic Neuropathy
This pilot data demonstrates an excitatory/inhibitory neurotransmitter imbalance in the brain of in patients with DN and positive sensory symptoms compared to pain free HC subjects (Academic Radiology)
Do Twin Pregnant Women Require Twice as Much Insulin as Singleton Pregnant Women?
In twin pregnancies, the weekly increase in insulin dose between 14 and 27 weeks was doubled compared with singleton pregnancies (Diabetes Care)
Does Diabetes Care Differ by Type of Chronic Comorbidity?
Our study indicates that diabetes care varies by types of comorbidity. Concordant illnesses result in similar or better care, regardless of visit frequency. Discordant illnesses are associated with diminished care: an effect that decreases as visit frequency increases (Diabetes Care)
Stratifying healthcare costs using the Diabetes Complication Severity Index
The DCSI score is a useful tool for predicting direct healthcare costs. The DCSI can be used to triage high-risk patients for more focused secondary prevention interventions at primary care level, in a bid to lower overall healthcare costs (Diabetes and Its Complications)
Societal correlates of diabetes prevalence: An analysis across 94 countries
Macro-level societal factors are associated with diabetes prevalence. Investigating how these factors affect individual-level diabetes risk may offer further insight into policy-level interventions (Diabetes Research and Clinical Practice)
Initial therapy with the fixed-dose combination of sitagliptin and metformin
Compared with pioglitazone, initial therapy with a FDC of sitagliptin and metformin led to significantly greater improvement in glycaemic control as well as a higher incidence of prespecified gastrointestinal adverse events, a lower incidence of oedema and weight loss vs. weight gain (Diabetes, Obesity and Metabolism)
Trial of Intravitreal Bevacizumab or Laser Therapy (BOLT) in the Management of Diabetic Macular Edema
This study provides evidence supporting longer-term use of intravitreous bevacizumab for persistent center-involving CSME (Archives of Ophthalmology)
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