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Diabetes News August 7th 2009

August 7th 2009

Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group
Overall, insulin glargine use was not associated with an increased risk of all cancers or site-specific cancers in Scotland over a 4 year time frame (Diabetologia)

Role of Self Monitoring of Blood Glucose
Recommendations from the Canadian Agency for Drugs and Technologies in Health and the (Canadian Diabetes Association)

Optimal insulin regimens in type 2 diabetes mellitus: systematic review and meta-analyses
Greater HbA1c reduction may be obtained in type 2 diabetes when insulin is initiated using biphasic or prandial insulin rather than a basal regimen, but with an unquantified risk of hypoglycaemia (Diabetologia)

Predictors of Insulin Regimens and Impact on Outcomes in Youth with Type 1 Diabetes: The SEARCH for Diabetes in Youth Study
Youth using insulin pumps had the lowest A1C; A1C was unacceptably high in adolescents. There is a need to more fully assess and understand factors associated with insulin regimens recommended by providers and the influence of race/ethnicity, education, and socioeconomic status on these treatment recommendations and to develop more effective treatment strategies, particularly for adolescents (Journal of Pediatrics)

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men
Low circulating levels of sex hormone–binding globulin are a strong predictor of the risk of type 2 diabetes in women and men. The clinical usefulness of both SHBG genotypes and plasma levels in stratification and intervention for the risk of type 2 diabetes warrants further examination (New England Journal of Medicine)

Evaluation of an online Diabetes Needs Assessment Tool (DNAT) for health professionals: a randomised controlled trial
This paper describes the study design of a randomised controlled trial to evaluate the effectiveness of using an interactive online Diabetes Needs Assessment Tool (DNAT), that builds a learning curriculum based on identified knowledge gaps, compared with conventional self-directed learning. 27-page PDF (Trials Journal)

The Pathogenetic Role of Cortisol in the Metabolic Syndrome: A Hypothesis
The present review summarizes the evidence on the potential role of cortisol in the pathogenesis of MetS and discusses new therapeutic approaches for these patients (Journal of Clinical Endocrinology & Metabolism)

Diabetic retinopathy screening in general practice – A pilot study
General practice based DR screening was feasible and acceptable in the clinics studied, but photograph quality was an issue (RACGP)

The effects of hyperglycaemia on thrombin-activatable fibrinolysis inhibitor
The aim of this study was to determine the effect of hyperglycaemia on thrombin-activatable fibrinolysis inhibitor (Schattauer)

Economic Outcomes Associated with Microvascular Complications of Type 2 Diabetes Mellitus: Results from a US Claims Data Analysis
This study indicates that in patients with T2DM, MVC is associated with significant consumption of healthcare resources. Mean total costs with MVC were almost double those of patients without MVC over a 12-month period (PharmacoEconomics)

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