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Diabetes News December 9th 2011

December 9th 2011

Draft Guidance – Artificial Pancreas Device Systems
Draft Guidance for Industry and Food and Drug Administration Staff – The Content of Investigational Device Exemption (IDE) and Premarket Applications for Artificial Pancreas Device Systems. This guidance document is being distributed for comment purposes only (Food and Drug Administration, USA)

Welsh Endocrinology and Diabetes Society
A new website – the Welsh Endocrinology and Diabetes Society (WEDS) was established as an educational forum for specialist physicians delivering Diabetes and Endocrinology services for the people of Wales (WEDS)

Protein oxidation markers in women with and without gestational diabetes mellitus: A possible relation with paraoxonase activity
There is evidence of a possible association between protein oxidation and decreased PON1 activity in GDM. The increase in protein oxidation parameters in the GDM group leading to decreased PON1 activity might, we think, create a predisposition for clinical complications in GDM group (Diabetes Research and Clinical Practice)

Gestational diabetes and subclinical inflammation: Evaluation of first year postpartum outcomes
Elevated hsCRP levels could be predictors of progression to T2DM later in life in patients with GDM (Diabetes Research and Clinical Practice)

Serum prolidase activity and oxidative status in patients with diabetic neuropathy
The presence of high TOS and OSI levels together with low levels of TAS in diabetic patients with or without neuropathy may support a role of oxidative stress in the pathogenesis of diabetes mellitus (Neurological Sciences)

Tracking Blood Glucose and Predicting Prediabetes in Chinese Children and Adolescents: A Prospective Twin Study
Our longitudinal study of 1,766 subjects represents the largest study to date of gender-specific tracking patterns of both FPG and 2hPG. This report contributes new information to our understanding regarding the dynamic change of plasma glucose from children to adulthood (PLoS ONE)

Differences in metabolic effects of twice daily versus multiple daily insulin injections in children with type 1 diabetes
It was concluded that MDI from diagnosis results in better glycaemic control and a trend towards less weight gain at 12 months than BD. Children who start on BD and then switch to MDI after 12 months do not show the same benefit (Practical Diabetes)

Oral Care Practices and A1C Among Youth With Type 1 and Type 2 Diabetes
Clinicians should beware that children with diabetes tend to have poor oral hygiene practices. Dry mouth may indicate periodontal bone loss in children with diabetes (Journal of Periodontology)

New iInvestigational compound Dapagliflozin
New data show investigational compound dapagliflozin when added to glimepiride maintained reductions in blood sugar levels in adults with type 2 diabetes over 48 weeks of treatment (Bristol-Myers Squibb)

Categories: News Pre-2012

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