Muscling in on Type 2 diabetes
Research by kinesiology investigator Dustin Hittel, PhD, has proven that muscle in extremely obese individuals produces large amounts of a protein called myostatin, which normally inhibits muscle growth—suggesting that for Type 2 diabetics, and the very obese, the task of getting healthy may be more difficult than initially thought (insciences)
Health Statistics Wales 2009
One fifth of adults (21 per cent) were classified as obese,and one in five children (20 per cent) were classified as obese (Welsh Assembly Government)
Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates
Reduced-calorie diets result in clinically meaningful weight loss regardless of which macronutrients they emphasize (NEJM)
Weight-Loss Diets for the Prevention and Treatment of Obesity
Like cholera, obesity may be a problem that cannot be solved by individual persons but that requires community action – Editorial (NEJM)
Post-Prandial v. Fasting Glucose: An End to the Debate?
In Patients With Existing CVD, Study Finds No Difference (Market Watch)
FDA Approves Sanofi-Aventis’s Apidra(R) SoloSTAR(R) – a Prefilled Disposable Insulin Pen
Sanofi-aventis announced today that the U.S. Food and Drug Administration approved Apidra(R) SoloSTAR(R) (insulin glulisine [rDNA origin] injection), a prefilled disposable pen containing rapid-acting insulin analog Apidra(R), which is indicated to improve glycemic control in adults and children (4 years and older) with type 1 diabetes or adults with type 2 diabetes (BioSpace)
American Diabetes Association and Novo Nordisk, Inc. Announce $1.2 Million Research Support
Studies to Look at Hormonal Influence on Weight, Type 2 Diabetes and Cardiovascular Disease (MSNBC)
Study examining role of genetics and environment in type 1 diabetes
Another 200 newborns in Georgia and Florida with high-risk genes for type 1 diabetes will be enrolled over the next year in a long-term study to determine how genetics and environment cause the disease (insciences)
Metabolic fate of plasma glucose during hyperglycemia in impaired glucose tolerance
Evidence for further early defects in the pathogenesis of type 2 diabetes (Endocrinology and Metabolism)
Association of Diabetes With Prostate Cancer Risk in the Multiethnic Cohort
Diabetes is a protective factor for prostate cancer across populations, suggesting shared risk factors that influence a common mechanism (American Journal of Epidemiology)
Long-term outcomes in patients with type 2 diabetes receiving glimepiride combined with liraglutide or rosiglitazone
Using data from LEAD-1 and epidemiologic evidence from the CORE diabetes model, projected rates of mortality, diabetes complications and healthcare costs over the long term favor liraglutide plus glimepiride over rosiglitazone plus glimepiride (Cardiovascular Diabetology)
The organisation & delivery of diabetes services in the UK: a scoping exercise
The National Institute for Health Research (via the SDO), supported by NHS Diabetes has commissioned King’s College London to undertake a scoping exercise to help set the priorities for health services research in diabetes (NHS Diabetes)
Will new diabetes targets neglect high-risk patients?
The new diabetes targets may not be achievable, will be too aggressive and won’t target those at highest risk, warns Dr Martin Hadley-Brown. But Dr Jonathan Graffy argues that by setting targets across a range of blood sugars, the indicators will extend benefits to more patients and drive improvement (PULSE)
Chronically-ill to send GP daily reports with computers
Early indications from trials show it can reduce the number of hospital trips – scheduled and emergency – in chronic obstructive pulmonary disease, stroke and diabetic patients by almost a third (Scotsman)
Safety in the ICU – Is Bedside Glucose Testing Safe For Our Patients?
It appears that there is yet another part of the system of care that needs to be not taken for granted, if we are to achieve normoglycemia in our patients more often, and to avoid unnecessary hypoglycemia (AACE)
Diabetes on the increase across the UK
Karen Addington, Chief Executive of JDRF, comments: ‘Other studies have shown that in children under five, incidence is increasing by about four per cent each year, with a five-fold increase in diagnoses in this age group in the last 20 years.’ (JDRF)
Merck launches $15 million diabetes outreach program
In an effort to close healthcare disparity gaps among at-risk diabetes populations – specifically African-American, Hispanic and Native American adults – Merck’s philanthropic arm will commit $15 million to its five-city outreach program (Medical Marketing and Media)
Insulin pump subsity program flawed and in need of urgent overhaul
The Rudd Labor Government’s insulin pump subsity program for Australian children with type 1 diabetes is fundamentally flawed and needs an urgent overhaul, according to Liberal Senator Guy Barnett and Hon. Judi Moylan MP, President of the Parliamentary Diabetes support Group (AHHA)
TuDiabetes 2nd Anniversary and 7000 Member Press Release
As our second anniversary approaches, I have put together a press release to help get the word out about the community to local media (TuDiabetes)
New HbA1c Leaflets
From 1 June 2009, the way in which HbA1c results are reported in the UK is changing. These leaflets explain why and how this will happen (NHS Diabetes)
Datamining finds new target for diabetes treatment
A team of researchers from Oxford and Southampton Universities have identified a new molecular player in insulin secretion process by mining a free database of 5 million drug compounds. This finding could spark a completely new class of drugs to treat type 2 diabetes (British Journal of Healthcare Computing and Information)
Rates of diabetes soar in the UK
The bulk of cases are type 2 diabetes -which is linked to being overweight or obese – the Journal of Epidemiology and Community Health reports (BBC)
UK sees diabetes cases rise by three-quarters
Obesity and unhealthy lifestyles fuel 74% increase in new cases (Guardian)
The effectiveness of nutritional education on the knowledge of diabetic patients using the health belief model
The efficacy of the health belief model in nutritional education to the diabetic patients was confirmed in the present study (Journal of Research in Medical Sciences)
Predictors of Diabetes-related Quality of Life after Transitioning to the Insulin Pump
Results indicate that individual and contextual factors may play a role in QOL as children transition to the insulin pump. Findings may guide efforts to support families through this challenging time and potentially inform candidacy for transition to the pump (Journal of Pediatric Psychology)
Preliminary Report of the NICE-SUGAR study
Hypoglycemia and what it may mean for patient safety (American Association of Clinical Endocrinologists)
Association of Elevated Fasting Glucose With Increased Short-term and 6-Month Mortality in ST-Segment Elevation and Non–ST-Segment Elevation Acute Coronary Syndromes
Short-term and 6-month mortality was increased significantly with higher fasting glucose levels in patients across the spectrum of acute coronary syndromes, thus extending this relation to patients with non–ST-segment elevation myocardial infarction (Archives of Internal Medicine)
The relationship between glycemic control and platelet activity in type 2 diabetes mellitus
Our results suggested a close relationship between poor glycemic control and increased platelet activity in patients with type 2 DM (Journal of Diabetes and its Complications)
Diabetics Less Likely to Develop Acute Respiratory Failure During Sepsis
Among patients with sepsis, diabetics are less likely than others to develop acute respiratory failure, according to a report in the February 13th issue of Critical Care (Medscape)
Repair effect of diabetic ulcers with recombinant human epidermal growth factor loaded by sustained-release microspheres
Overall locally sustained delivery of rhEGF from biodegradable PLGA microspheres may serve as a novel therapeutic strategy for diabetic ulcer repair (PubMed)
Self Monitoring of Blood Glucose (SMBG) in Non-Insulin treated Type 2 Diabetes
Executive Position Statement (NZSSD)
Diabetic Papillopathy and Its Relation to Optic Nerve Ischemia
Presented are clinical data of a case of diabetic papillopathy and a literature review to delineate the typical published clinical characteristics and course of this disease process (PubMed)
Association between oral antidiabetic use, adverse events and outcomes in patients with type 2 diabetes
The occurrence of adverse events did not significantly impact glycaemic response to therapy. However, adverse events may lead to greater treatment switches for patients receiving metformin and add-on therapy for metformin-treated and sulphonylureas-treated patients (PubMed)
Important differences
Canadian Diabetes Association 2008 clinical practice guidelines and the consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes (Diabetologia)
Shock Wave Lithotripsy Does Not Increase Diabetes Risk
Contrary to an earlier report, shock wave lithotripsy does not increase the risk of diabetes, according to a paper in the January issue of Urology (Medscape)
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