Osmotic polyuria: an overlooked mechanism in diabetic nephropathy
Tubulo-interstitial pathology in diabetic nephropathy is thought to be caused by cell injury that is induced by high ambient glucose levels and increased proportions of glycated proteins (NDT, USA)
Adjust to Target in Type 2 Diabetes
Comparison of a simple algorithm with carbohydrate counting for adjustment of mealtime insulin glulisine (Diabetes Care, USA)
Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women
Consumption of green leafy vegetables and fruit was associated with a lower hazard of diabetes, whereas consumption of fruit juices may be associated with an increased hazard among women (Diabetes Care, USA)
Gender Counts When it Comes to Effective Diabetes Management, Prevention
A recently published study that suggests diabetes counseling, management and patient education should be presented differently to men and women could help FPs in their efforts (AAFP, USA)
Weight Change and Glycemic Control After Diagnosis of Type 2 Diabetes
A small-but-substantial group of patients had a mean weight trajectory that included a clinically significant weight loss. Weight-loss trajectories were strongly associated with better glycemic control when compared to weight gain (Journal of General Internal Medicine, USA)
Effects of inhaled human insulin on airway lining fluid composition in adults with diabetes
Inhaled human insulin (Exubera® (human insulin of rDNA origin) Inhalation Powder) causes small, early and reversible changes in pulmonary function in subjects with diabetes mellitus (European Respiritory Journal)
Neonatal Diabetes groundbreaking treatment offers hope
A team of researchers led by a physician at UC Davis Children’s Hospital has for the first time rapidly transitioned an infant with neonatal diabetes from injected insulin to a generic oral medication in an outpatient setting (Rocklin & Roseville Today, USA)
Danny wants to end pie and chips diet to beat killer diabetes
The defender, once rated as the world’s best in his position, beat diabetes to have a successful 20-year playing career (Evening Times, Scotland)
New plans to improve NHS care
Diabetes UK welcomes Lord Darzi’s report. Putting quality at the centre of the NHS is key to ensuring that people with diabetes receive the best care possible regardless of post code or cost (Diabetes UK)
New diabetes unit is launched at Rugby Hospital of St Cross
It has been funded by a £20,000 investment by University Hospitals Coventry and Warwickshire NHS Trust; donations of £56,000 from the Friends of the Hospital of St Cross and £20,000 from Diabetes UK (Coventry Telegraph, UK)
Change on the way for thousands of diabetes sufferers
It involves thousands of patients having their treatment switched from the University Hospital of North Staffordshire to new primary care centres in Stoke-on-Trent (The Sentinel, UK)
Glasgow dietitians awarded for health education for people with learning disabilities
The Research Award consists of funding of £1,000 to enable a dietitian to embark on a research project (British Dietetic Association)
In the U.S. and Holland, Diabetes Looks Different
On average, the U.S. system spends about $6,000 per person on health care, including whatever the government, employers and individuals pay out of pocket. For less than half that — about $2,700 — the Dutch get better care, research indicates (NPR)
$5 million for new rural Alberta diabetes management project
The Alliance for Canadian Health Outcomes Research in Diabetes (ACHORD) will receive $5 million over the next five years from Alberta Health and Wellness for a new collaborative outreach project to support diabetes care and management in rural Alberta (CNW, Canada)
Screening for Type 2 Diabetes Mellitus in Adults
U.S. Preventive Services Task Force (AHRQ, USA)
GGT and ALT levels may help predict incident diabetes in adults
Analysis of data from 787 patients with incident diabetes and 2,224 subjects with no diabetes found a significant association between incident diabetes and high plasma levels of GGT and ALT (Diabetes Pro, USA)
Rosiglitazone associated with slower progression of diabetic retinopathy
Patients with diabetes who take rosiglitazone may be less likely to develop proliferative diabetic retinopathy, according to a recently published report (Endocrine Today, USA)
OUTLOOK US diabetes committee could delay key AstraZeneca drug
A key U.S. committee on diabetes could make recommendations this evening that might further delay AstraZeneca Plc.’s next major product, diabetes drug saxagliptin to be marketed under the name Onglyza (Trading Markets, USA)
New Spanish Consumer Guide Compares Diabetes Meds
To help combat one of the most serious health issues facing Hispanics in the United States, a new Spanish language guide to type 2 diabetes has been released (Washington Post, USA)
OneTouch® PingTM Glucose Management System Cleared by FDA
Animas Announces Clearance of Uniquely Integrated Meter/ Pump System with Remote Insulin Delivery Capabilities and Compatible Software (Animas, USA)
Australian Government’s timely initiative on insulin pump subsidy
The rising incidence of Type 1 diabetes in children underlines the importance of the Rudd Government’s decision to subsidise the cost of insulin pumps (Department of Health and Aging, Australia)
FDA Approves SPrandiMet, a Replaglinide and Metformin Fixed-Dose Combination Tablet for Treatment of Type 2 Diabetes
Sciele Pharma, Inc. and Novo Nordisk Inc. today announced that the U.S. Food and Drug Administration approved PrandiMet™ (repaglinide and metformin HCl) tablets, the first and only fixed-dose combination of the fast-acting secretagogue replaglinide (also known as Prandin®) and insulin sensitizer, metformin, for the treatment of type 2 diabetes (BioSpace)
Economic modelling for vascular checks
The technical consultation outlines the modelling work the Department of Health has undertaken in the last year to establish the clinical and cost effectiveness of the vascular checks programme. The consultation will be open from Tuesday until Tuesday 12th August (DoH, UK)
FDA Ponders Requiring Heart Studies for Diabetes Drugs
The FDA is summoning a panel of experts to consider whether drug makers should be forced to study the cardiovascular effects of diabetes drugs (Wall Street Journal, USA)
Type 1 diabetes in children still on the rise
The incidence of new cases of Type 1 diabetes in children is rising at around 3% a year, according to a report released today by the (AIHW, Australia)
Incidence of Type 1 diabetes in Australia 2000-2006: first results
This bulletin presents the latest available (up to 2006) national data on new cases of Type 1 diabetes for all ages from Australia’s National Diabetes Register (AIHW, Australia)
Blood Glucose Measurement in Patients with Suspected Diabetic Ketoacidosis
A Comparison of Abbott MediSense PCx Point-of-Care Meter Values to Reference Laboratory Values (Emergency Nurses Association, USA)
Diabetes sufferers may soon draw breath to take new treatment
A treatment being developed by Victorian scientists involves a drug-delivery technique in which patients use a palm-sized device to inhale nanosized particles of insulin (The Age, Australia)
Neuroendocrine sleep architecture altered in patients with type 1 diabetes
When subjectively analyzing the quality of sleep by mood and symptoms after sleep, the researchers found that type 1 diabetics had less restorative sleep (American Diabetes Association)
Internal body signals important for diabetes research
A joint research project between Sweden and the USA has uncovered a so far unknown signal network involving the cells in the pancreas (European Commission)
Evidence for inter-individual heterogeneity in the glucose gradient across the human RBC membrane and its relationship to hemoglobin glycation
The data demonstrate inter-individual heterogeneity in glucose gradients across RBC membranes which may affect Hb glycation and have implications for diabetes complications risk and risk assessment (Diabetes)
Baseline serum 25-hydroxy vitamin D is predictive of future glycaemic status and insulin resistance
This prospective study reports inverse associations between baseline serum 25(OH)D and future glycemia and insulin resistance (Diabetes)
Physical Activity and Insulin Sensitivity. The RISC Study
Accumulated daily physical activity is a major determinant of insulin sensitivity (Diabetes)
Dietary advice for the prevention of type 2 diabetes mellitus in adults
The aim of this systematic review is to assess the effects of type and frequency of dietary advice for the prevention of type 2 diabetes mellitus (Cohrane Library)
Call to rethink child BMI testing
Using a child’s body mass index (BMI) as a measure of the success of exercise targets may be misleading, say experts (BBC)
The Metabolic Syndrome and Incident Diabetes: Current State of the Evidence
The metabolic syndrome, however defined, is associated more strongly with incident diabetes than previously demonstrated for coronary heart disease. Its clinical value for diabetes prediction remains uncertain (Diabetes Care)
Risk prediction of cardiovascular disease in type 2 diabetes: A risk equation from the Swedish National Diabetes Register
This more simplified risk equation enables 5-year risk prediction of CVD based on easily available non-laboratory predictors in clinical practice and HbA1c, elaborated in a large observational study obtained from the normal patient population with age up to 70 years (Diabetes Care)
The Neuropad test may help to screen patients with diabetic neuropathy
These results suggest that patients with diabetic neuropathy may be screened with the Neuropad test (American Diabetes Association)
New Molecular Trigger Described for Hypertension, Diabetes
A newly discovered molecular malfunction may explain the development of high blood pressure, diabetes and immune problems, researchers report (Washington Post, USA)
Medtronic boosts investment in diabetes devices
Medtronic Inc is boosting investment in its fast-growing diabetes unit as it aims to convert more diabetics to insulin pumps and continuous glucose monitors (Reuters)
Type 2 Diabetes Mellitus and Cognitive Decline in Two Large Cohorts of Community-Dwelling Older Adults
Type 2 DM and longer duration of DM are similarly related to cognitive impairment and decline in men and women (Journal of the American Geriatrics Society)
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