Diabetes News June 10th 2011

Getting type 1 diabetes sorted
A unique project commissioned by NHS Diabetes and led by Leeds Metropolitan University is aiming to improve the care for children and young people with type 1 diabetes. Getting Sorted website (JDRF)

High-risk diabetic nephropathy patients: The outcome of evidence-based clinical practice in an outpatient clinic
A combined diabetes–renal consultant clinic is an effective intervention to improve the outcome of high-risk diabetics with progressive diabetic nephropathy (Diabetes Research and Clinical Practice)

Pregravid cardiometabolic risk profile and risk for gestational diabetes mellitus
The risk of GDM increased with the number of cardiometabolic risk factors (P < .001); adverse levels of both body mass index and glucose were associated with a 4.6-fold increased risk of GDM, compared with women with normal levels (American Journal of Obstetrics & Gynecology)

Stereology of the placenta in type 1 and type 2 diabetes
Maternal glycaemia appears to influence capillary, but not stromal, development. This suggests that factors other than glycaemia have a role in placental development in pre-gestational diabetes (Placenta)

Conference -The Older Patient: Midlife Risk Factors to Later Comorbidity
Following the success of our previous symposia series, the latest GM conference The Older Patient: midlife risk factors to later comorbidity, will take place at the Royal Society of Medicine on Wednesday 19th October. This conference will review best practice in managing a range of common diseases and offer practical advice on meeting the complex needs of the ageing patient (Geriatric Medicine)

A Comprehensive Diabetes Strategy for New Brunswickers 2011-15
This strategy is based on lessons learned from local practices and strategies from other jurisdictions as well as published, researched interventions and systematic reviews. It is the fi rst strategy developed under the Chronic Disease Prevention and Management Framework (Department of Health, Canada)

Treatment of diabetic foot ulcers: A comparative study of extracorporeal shockwave therapy and hyperbaric oxygen therapy
ESWT is more effective than HBOT in chronic diabetic foot ulcers. ESWT-treated ulcers showed significant improvement in blood flow perfusion rate and cell activity leading to better healing of the ulcers relative to HBOT in chronic diabetic foot ulcers (Diabetes Research and Clinical Practice)

The feasibility of contact heat evoked potentials for detection of diabetic neuropathy
CHEP can be used to detect early A-delta fiber damage in diabetic patients with minimal neuropathy (Muscle & Nerve)

Islet-Like Cell Aggregates Generated from Human Adipose Tissue Derived Stem Cells Ameliorate Experimental Diabetes in Mice
h-ASC is an ideal population of personal stem cells for cell replacement therapy, given that they are abundant, easily available and autologous in origin. Our findings present evidence that h-ASCs could be induced to differentiate into physiologically competent functional islet like cell aggregates, which may provide as a source of alternative islets for cell replacement therapy in type 1 diabetes (PLoS ONE)

JDRF to Support Selecta’s Development of Tolerogenic Type 1 Diabetes Vaccine
The Juvenile Diabetes Research Foundation (JDRF) is providing milestone-based financial support and expertise to aid Selecta Bioscience’s development of a vaccine for the treatment of type 1 diabetes (Genetic Engineering & Biotechnology News)

FDA Approves Updates to Lilly’s Humalog® (insulin lispro injection [rDNA origin]) Label
Update for Insulin Pump Use Provides an Additional Option for Children With Type 1 Diabetes and Extends Amount of Time People Can Use and Store Humalog Insulin in Their Pumps (Lilly)

U.S. District Court Rules in Favor of Lilly in Amylin Litigation
U.S. District Court for the Southern District of California ruled in Lilly’s favor, vacating a temporary restraining order and denying a request by Amylin Pharmaceuticals for a preliminary injunction that sought to impose restrictions on the Lilly Diabetes sales force and other relief. (Lilly)