Diabetes News May 6th 2011

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy
This Review, focuses on key proinflammatory molecules and pathways implicated in the development and progression of diabetic nephropathy. Advances in the understanding of the roles that these inflammatory pathways have in the context of diabetic nephropathy will facilitate the discovery of new therapeutic targets (Nature Reviews Nephrology)

Marrying contradictions: Healthcare professionals perceptions of empowerment in the care of people with Type 2 Diabetes
Models of empowerment, which promote that HCPs bring clinical expertise and patients ‘lay’ expertise of illness to the medical encounter, are inadequately descriptive of how empowerment approaches are actually engaged with, by HCPs (Patient Education and Counseling)

Intervention in Women With Gestational Diabetes Mellitus Reduces Diabetes Risk Factors
To pilot, among women with gestational diabetes mellitus the feasibility of a prenatal/postpartum intervention to modify diet and physical activity similar to the Diabetes Prevention Program. The intervention was delivered by telephone, and support for breastfeeding was addressed (Diabetes Care)

Physical Activity Advice Only or Structured Exercise Training and Association With HbA1c Levels in Type 2 Diabetes
Structured exercise training that consists of aerobic exercise, resistance training, or both combined is associated with HbA1c reduction in patients with type 2 diabetes (JAMA)

Fasting Plasma Glucose and Clustering of Cardiometabolic Risk Factors in Normoglycemic Outpatient Children and Adolescents
In outpatient children and adolescents, higher FPG within the normal range is associated with several CMRF, independent of obesity. Thus the simple measurement of FPG may help identify subjects who warrant some monitoring in relation to cardiovascular risk (Diabetes Care)

Heart-Type Fatty Acid Binding Protein (H-FABP)
Relationship with Arterial Intima-Media Thickness and Role as Diagnostic Marker for Atherosclerosis in Patients with Impaired Glucose Metabolism PDF (Cardiovascular Diabetology)

Revolution in wound care?
Inexpensive, easy-to-use cotton candy-like glass fibers appear to speed healing in initial venous stasis wound trial (American Ceramic Society)

Advances in Healing the Diabetic Wound
This lecture by our renowned Editor John Steinberg, DPM presents several of the newest technologies in use for healing challenging diabetic foot wounds (Present Podiatry)

FDA Approves Tradjenta (linagliptin) Tablets for the Treatment of Type 2 Diabetes
First DPP-4 inhibitor approved at one dosage strength; no dose adjustment recommended for patients with type 2 diabetes who have kidney or liver impairment (PharmaLive)