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Diabetes News May 7th 2010

May 7th 2010

Diagnosis and management of type 1 diabetes in children, young people and adults
This evidence-based guideline is concerned only with Type 1 Diabetes and covers the NHS care that should be available to adults with Type 1 diabetes (NHS Evidence, UK)

Type 1 diabetes in children – Emergency management
The aim of this review is to provide information to improve the early recognition of DKA and to provide guidelines for the initial management of DKA in the nonspecialist setting (Royal Australian College of General Practitioners)

Are clinical practical guidelines useful for health services and health workforce planning?
Clinical practice guidelines are potentially useful for health services and health workforce planning, but would be more valuable for this purpose if they contained more detail about care protocols and specific skills and competencies, especially for subpopulations who would be expected to have reduced capacity for effective self-care (Diabetic Medicine)

New Interactive Diabetes Resource Available Online
Latest online tool allows users to learn at own pace (Canadian Diabetes Association)

5% lidocaine medicated plaster in painful diabetic peripheral neuropathy (DPN): a systematic review
The results suggest that the effects in pain reduction of 5% lidocaine medicated plaster are comparable to those of amitriptyline, capsaicin, gabapentin and pregabalin. Topical agents such as 5%LMP may be associated with fewer and less clinically significant adverse events than is the case for systemic agents (Swiss Medical Weekly)

A systematic review of scoring systems for diabetic foot ulcers
Many scoring systems exist for classification of the diabetic foot, few of which have been validated. Detailed scoring systems offer a valuable method for the comparison of data from different diabetic foot centres (Diabetic Medicine)

Joslin Research Shows Insulin Guards Against Artery Damage
Long suspected of worsening artery damage in patients with diabetes, insulin instead protects blood vessels, a new study by Joslin Diabetes Center scientists indicates (Joslin Diabetes Center)

The relationship between self-monitored blood glucose values and glycated haemoglobin in insulin-treated patients with Type 2 diabetes
These data provide patients and clinicians information on the relationship between HbA1c and SMBG measurements in patients with T2DM, and support the value of frequent blood glucose measurements for assessing overall glycaemic control (Diabetic Medicine)

Role of vildagliptin in managing type 2 diabetes mellitus in the elderly
Because vildagliptin does not expose patients to hypoglycaemic risk, it seems particularly suited to oral therapy of T2DM in the elderly (PubMed Diabetes)

Novo Nordisk partners with international scientific community
The trial named LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) aims to assess and confirm the cardiovascular safety of the company’s new once-daily human GLP-1 analogue liraglutide and subsequently test the ability of liraglutide to improve cardiovascular outcomes (Pharmacy Europe)

Ipsen’s partner Roche announces that Taspoglutide meets its primary endpoint in a key phase III clinical trial
Taspoglutide demonstrates superiority in HbA1c change versus placebo as add-on to metformin and pioglitazone (PharmaLive)

Safety and tolerability of high doses of taspoglutide
Safety and tolerability of high doses of taspoglutide, a once-weekly human GLP-1 analogue, in diabetic patients treated with metformin: a randomized double-blind placebo-controlled study (Diabetic Medicine)

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