Diabetes News November 25th 2011

Mother of five wins award for diabetes website
Angela Allison, a Preston mother of five, was winner of the inaugural Quality in Care (QiC) Diabetes People’s Award last week. The awards ceremony was held at Sanofi’s headquarters in Guildford on Wednesday November 16 (Diabetes UK)

Medtronic Receives FDA Approval for Next Generation Professional Continuous Glucose Monitoring
iPro®2 Simplifies Professional CGM for Improved Diabetes Therapy Management (Medtronic)

Short- and Long-Term Effects of Real-Time Continuous Glucose Monitoring in Patients With Type 2 Diabetes
Subjects with type 2 diabetes on prandial insulin who used RT-CGM intermittently for 12 weeks significantly improved glycemic control at 12 weeks and sustained the improvement without RT-CGM during the 40-week follow-up period, compared with those who used only SMBG (Diabetes Care)

Repeat measurements of glycated haemoglobin A1c and N-terminal pro-B-type natriuretic peptide: divergent behaviour in diabetes mellitus
N-terminal pro-B-type natriuretic peptide and HbA1c concentrations significantly diverged over a 1-year period. NT-proBNP was the most potent predictor of outcome at baseline and follow-up, and changes in NT-proBNP concentrations were linked to an altered risk profile, unlike changes in HbA1c levels (European Journal of Clinical Investigation)

Impact of FDA Guidance for Developing Diabetes Drugs on Trial Design: From Policy to Practice
The present review summarizes current attempts to streamline trial design and management to meet the requirements efficiently while adhering to the highest scientific standards (Metapress)

New-onset diabetes and cardiovascular events in essential hypertensives: A 6-year follow-up study
Our findings indicate the high incidence of NOD and its close association with stroke in essential hypertension. Poorer control of hypertension appears to be a common denominator of both NOD and stroke in this setting (International Journal of Cardiology)

Influence of preprandial vs. postprandial insulin glulisine on weight and glycaemic control in T2D
Postprandial glulisine administration provided similar glycaemic control and was non-inferior to preprandial administration on weight gain, without additional risk of severe hypoglycaemia, showing dosing flexibility and the feasibility of such approach when clinically indicated (Diabetes, Obesity and Metabolism)

Haptoglobin Genotype Predicts Development of Coronary Artery Calcification in a Prospective Cohort of Patients with Type 1 Diabetes
Hp genotype may aid prediction of accelerated coronary atherosclerosis in subjects with type 1 diabetes. Hp genotype did not predict CAC progression in individuals without diabetes (Cardiovascular Diabetology)