2010 Annual Evidence Update on Diabetic Retinopathy
Changes and additions made since August 2009 are highlighted in the commentary pages in red (NHS Evidence Diabetes)
Liraglutide: final appraisal determination
After considering the feedback from consultation, the Appraisal Committee has prepared a Final Appraisal Determination (FAD) on liraglutide for the treatment of type 2 diabetes mellitus and submitted it to the Institute (NICE)
Children’s charter for diabetes
Diabetes UK developed this charter with involvement from children and young people with diabetes, their carers and healthcare professionals (Diabetes UK)
Metabolic memory: a vascular perspective
The hypothesis proposes that structural and functional changes in the microcirculation interact within the vascular continuum with larger arteries. This interaction may lead to subsequent upstream endothelial dysfunction, atherosclerosis and vascular complications. The underlying microvascular structural changes may be more long-term and possibly mediate the “metabolic memory” (Cardiovascular Diabetology)
The older patient: bridging the gap between primary and secondary care
Geriatric Medicine symposium – Wednesday October 27th, Royal Society of Medicine, London (Wednesday October 27th, Royal Society of Medicine, London)
Volume 24, Issue 5, Pages 289-360 (September-October 2010)
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice
Although KU-32 did not improve glucose levels, HbA1c (glycated haemoglobin) or insulin levels, it reversed the NCV and sensory deficits in WT but not Hsp70 KO mice (American Society for Neurochemistry)
High levels of serum prolactin protect against diabetic retinopathy by increasing ocular vasoinhibins
Circulating PRL influences the progression of DR after its intraocular conversion to vasoinhibins. Inducing hyperprolactinemia may represent a novel therapy against DR (Diabetes)
Adiponectin, resistin and IL-6 plasma levels in subjects with diabetic foot and possible correlations with clinical variables and cardiovascular co-morbidity
Our study demonstrated that diabetic subjects with diabetic foot showed in comparison with diabetics without diabetic foot higher IL-6 and resistin plasma levels, lower adiponectin plasma levels (Cardiovascular Diabetology)
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