Effects of Dipeptidyl Peptidase-4 Inhibitors on Cardiovascular Disease T2D

DPP-4 inhibitors have some CV protective effects in T2DM in addition to their antidiabetic actions. Additional benefits include lowering the blood pressure, improving the lipid profile and the endothelial dysfunction, decreasing the macrophage-mediated inflammatory response, and reducing myocardial injury. Further investigation in a large cohort is warranted to assess the exact mechanisms of CV protective effects of DPP-4 inhibitors (Journal of Diabetes Research)