Gestational diabetes induces alterations in the function of neonatal endothelial colony-forming cells

Intrauterine exposure of endothelial colony-forming cells (ECFCs) to GDM induces unique phenotypic alterations. The resistance of GDM-exposed ECFCs to hyperglycemia-induced senescence and decreased p38MAPK activation suggest that these progenitor cells have undergone changes that induce tolerance to a hyperglycemic environment (Pediatric Research)