HbA1c Categories & ß-Cell Function Relative to Insulin Sensitivity in Obesity

Overweight/obese adolescents with HbA1c in the at-risk/prediabetes category demonstrate impaired ß-cell function relative to insulin sensitivity, a metabolic marker for heightened risk of type 2 diabetes. Thus, HbA1c may be a suitable screening tool in large-scale epidemiological observational and/or interventional studies examining the progression or reversal of type 2 diabetes risk (Diabetes Care)