Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

Glycaemic response to metformin is heritable, thus glycaemic response to metformin is, in part, intrinsic to individual biological variation. Further genetic analysis might enable us to make better predictions for stratified medicine and to unravel new mechanisms of metformin action (The Lancet Diabetes & Endocrinology)