Applying the DSS across T2D clinical trial populations with different CV risk revealed significantly increased risk for ACM and CV death with higher DSS stage. The DSS may benefit from assessment in other T2D populations and with evaluation of the impact of additional outcomes, such as heart failure (Diabetes, Obesity and Metabolism)
Diabetes News
Category: Management
Therapeutic inertia related to the injectable glucagon-like peptide-1 receptor agonists dulaglutide and semaglutide in patients with type 2 diabetes in UK primary care
Multiple examples of therapeutic inertia were identified, including first prescription at HbA1c levels considerably above target and failure to escalate to optimal doses even with evidence of suboptimal metabolic control. A substantial proportion of patients therefore did not achieve optimal HbA1c targets (Diabetes, Obesity and Metabolism)
Diabetes Management in Chronic Kidney Disease: Synopsis of the KDIGO 2022 Clinical Practice Guideline Update
The KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease is an update of the 2020 guideline from Kidney Disease: Improving Global Outcomes (Annals of Internal Medicine)
Addressing health inequalities in diabetes through research: Recommendations from Diabetes UK’s 2022 health inequalities in diabetes workshop
This position statement outlines recommendations to address the urgent need to tackle health inequalities in diabetes through research and calls on the diabetes research community to act upon these recommendations to ensure future research works to eliminate unfair and avoidable disparities in health (Diabetic Medicine)
Observational Evaluations of Disease Management Programs for Diabetes: The Proof Is in the Concept
Despite the introduction of multiple novel therapeutics over the past two decades, rates of control in type 2 diabetes (T2D) and its comorbidities remain suboptimal and may have even declined (Diabetic Care)
‘No one ever asks about something that actually is relevant to my life’
A qualitative study of diabetes and diabetes care experiences of young women with type 2 diabetes during their reproductive years (Diabetic Medicine)
Diabetes high impact interventions
An evidence based and quality assured programme that aims to support the person and their family members and carers in developing attitudes, beliefs, knowledge and skills to self-manage diabetes and reduce their chances of deterioration or exacerbation (NHS England)
Care processes in people in remission from type 2 diabetes: A cohort study using the National Diabetes Audit
People coded with remission of type 2 diabetes were less likely to receive diabetes care processes than those without such coding (Diabetic Medicine)
Application of the PDCA Cycle for Managing Hyperglycemia in Critically Ill Patients
To the best of our knowledge, this is the first report on using the PDCA cycle to manage and control glucose levels in critically ill patients (Diabetes Therapy)
A personalized multi-interventional approach focusing on customized nutrition, progressive fitness, and lifestyle modification resulted in the reduction of HbA1c, fasting blood sugar and weight in type 2 diabetes
The findings indicate that a comprehensive and multi-interventional diabetes care program involving personalized nutrition, fitness, and lifestyle modification such as SDRP, help in significant and sustained improvements in HbA1c level, glycaemic control, and weight loss in adults with type 2 diabetes (BMC Endocrine Disorders)
Management of hyperglycaemia in type 2 diabetes, 2022
A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (Diabetologia)
Trends in the Association Between Diabetes and Cardiovascular Events, 1994-2019
In this large, population-based study, the magnitude of the association between diabetes and risk of cardiovascular events decreased, while that between CVD and such events remained stable. These results suggest that diabetes is still an important cardiovascular risk factor but no longer equivalent to CVD—a change that likely reflects the use of modern, multifactorial approaches to diabetes (JAMA)
Role of Primary Care Clinicians in the Management of Patients With Type 2 Diabetes and Cardiorenal Diseases
This article presents a clinical perspective with multidisciplinary collaboration on a patient case representative of those seen in routine clinical practice (Clinical Diabetes)
Long-Term Outcomes Among Young Adults With Type 2 Diabetes, Based on Durability of Glycemic Control: Results From the TODAY Cohort Study
Higher baseline HbA1c concentration and FG variability during year 1 accurately predicted youth with T2D who will experience metabolic decompensation and comorbidities. These values may be useful tools for clinicians when considering early intensification of therapy (Diabetes Care)
Automated insulin delivery: benefits, challenges, and recommendations. A Consensus Report of the Joint Diabetes Technology Working Group of the European Association for the Study of Diabetes and the American Diabetes Association
We outline a list of considerations for regulatory agencies, manufacturing companies, international and national professional societies, funding bodies, researchers, healthcare professionals, and people with diabetes to take into careful consideration (Diabetologia)
Normal and disordered gastric emptying in diabetes: recent insights into (patho)physiology, management and impact on glycaemic control
This review focuses on recent insights into the impact of gastric emptying on postprandial blood glucose, effects of diabetes therapy on gastric emptying and the management of disordered gastric emptying in diabetes (Diabetologia)
Management of Hyperglycemia in Type 2 Diabetes, 2022
A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (Diabetes Care)
Characteristics of new users of recent antidiabetic drugs in Canada and the United Kingdom
Although SGLT-2i, DPP-4i, and GLP-1 RAs are recommended as 2nd or 3rd line therapy for type 2 diabetes, important differences exist in the characteristics of users of these drugs. Contrary to existing guidelines, new users of DPP-4i had a higher prevalence of cardiovascular disease at baseline than new users of SGLT2i or GLP-1RA (BMC Endocrine Disorders)
Effects of Patient-Driven Lifestyle Modification Using Intermittently Scanned Continuous Glucose Monitoring in Patients With Type 2 Diabetes: Results From the Randomized Open-label PDF Study
Patient-driven lifestyle modification primarily focused on eating behavior using isCGM effectively lowered HbA1c levels in patients with T2D (Diabetes Care)
Adherence to antidiabetic treatment in primary health care in individuals with type 2 diabetes. A survey including socio-demographic, patient related and clinical factors
A low proportion of outpatients with T2D with regular primary care were adherent to diabetes treatment and this was associated with patient-related factors like answering patients’ treatment-related questions by the physician (Primary Care Diabetes)
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