Glycosmedia

Diabetes News Service

Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use.
To find out more, including how to control cookies, see here: Cookies Policy
  • News
  • Archive
  • Categories & Tags
  • Journal Watch
  • Updates
  • Education
  • Reviews
  • About us ▼
    • About Glycosmedia
    • Editorial Team
    • Frequently asked questions
    • Comments
    • Press Releases
    • Disclaimer
  • Subscribe
  • Contact

Diabetes News

Category: Nephrology


Renoprotective effect of SGLT-2 inhibitors among type 2 diabetes patients with different baseline kidney function: a multi-center study

October 8th 2021

This study supports the renoprotective benefit of real-world SGLT-2i use irrespective of patient baseline kidney function (Cardiovascular Diabetology)

Categories: Medication, Nephrology, News
Tags: SGLT2 inhibitors, Type 2 Diabetes

Categories: Medication, Nephrology
Tags: SGLT2 inhibitors, Type 2 Diabetes

Effects of SGLT-2 inhibitors on serum uric acid in patients with T2DM: A systematic review and network meta-analysis

October 7th 2021

SGLT-2 inhibitors could significantly reduce SUA levels in patients with T2DM, especially luseogliflozin (1 mg and 10 mg) and dapagliflozin (5 mg) possess the best effects. Therefore, SGLT-2 inhibitors look extremely promising as an anti-diabetes treatment option in patients with T2DM with high SUA (Diabetes, Obesity and Metabolism)

Categories: Medication, Nephrology, News
Tags: SGLT2 inhibitors, Type 2 Diabetes, uric acid

Categories: Medication, Nephrology
Tags: SGLT2 inhibitors, Type 2 Diabetes, uric acid

A Novel Hypothesis Linking Low Grade Ketonemia to Cardio-Renal Benefits with SGLT2-Inhibitors

October 4th 2021

In this review, we propose a novel hypothesis to link the pleiotropic effects of low grade ketonemia to the cardio-renal benefits seen with the SGLT2-inhibitors (Diabetes, Obesity and Metabolism)

Categories: Cardiovascular, Medication, Nephrology, News
Tags: ketonemia, SGLT2 inhibitors

Categories: Cardiovascular, Medication, Nephrology
Tags: ketonemia, SGLT2 inhibitors

Efficacy of tripterygium glycosides for diabetic nephropathy: a meta-analysis of randomized controlled trials

September 12th 2021

Efficacy of tripterygium glycosides for diabetic nephropathy: a meta-analysis of randomized controlled trials (BMC Nephrology)

Categories: Nephrology, News
Tags: tripterygium

Categories: Nephrology
Tags: tripterygium

Harnessing Metabolomics to Describe the Pathophysiology Underlying Progression in Diabetic Kidney Disease

May 12th 2021

Recent advances in metabolomics have clarified the role of dysregulated energy metabolism and uremic toxins in DKD pathophysiology (Current Diabetes Reports)

Categories: Nephrology, News
Tags: metabolomics

Categories: Nephrology
Tags: metabolomics

Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression

March 3rd 2020

In people with type 2 diabetes and normoalbuminuria, a high-risk score from the urinary proteomic classifier CKD273 was associated with an increased risk of progression to microalbuminuria over a median of 2·5 years, independent of clinical characteristics. However, spironolactone did not prevent progression to microalbuminuria in high-risk patients (The Lancet Diabetes & Endocrinology)

Categories: Nephrology, News
Tags: proteomics

Categories: Nephrology
Tags: proteomics

Effect of Insulin on Proximal Tubules Handling of Glucose: A Systematic Review

January 10th 2020

Available data points to an important insulin participation in renal glucose handling, including tubular glucose transport, but human studies with reproducible and comparable method are still needed (Journal of Diabetes Research)

Categories: Nephrology, News
Tags: glucose transport, insulin

Categories: Nephrology
Tags: glucose transport, insulin

Renal glucosuria is associated with lower body weight and lower rates of elevated systolic blood pressure: results of a nationwide cross-sectional study of 2.5 million adolescents

September 26th 2019

Renal glucosuria is associated with lower body weight and obesity as well as with lower rates of elevated systolic blood pressure (Cardiovascular Diabetology)

Categories: Nephrology, News
Tags: glucosuria

Categories: Nephrology
Tags: glucosuria

The Association Between Kidney Disease and Diabetes Remission in Bariatric Surgery Patients With Type 2 Diabetes

July 24th 2019

Remission of type 2 diabetes 5 years after bariatric surgery was associated with improvements in albuminuria and stabilized prognostic risk for CKD, but not with eGFR. Lower kidney function and greater prognostic risk at the time of bariatric surgery was linked to a lower likelihood of diabetes remission (American Journal of Kidney Diseases)

Categories: Nephrology, News
Tags: Type 2 Diabetes

Categories: Nephrology
Tags: Type 2 Diabetes

Lower Renal Threshold for Glucose Reabsorption in Type 1 Diabetes Mellitus (T1DM) May Explain the Smaller Contribution of SGLT2 Inhibitors to the Improvement of Plasma Glucose Control Compared with T2DM

June 13th 2019

These results indicate that it is advisable to estimate the renal threshold for glucose reabsorption prior to initiating SGLT2 inhibitor therapy in patients with T1DM (Diabetes Therapy)

Categories: Nephrology, News
Tags: SGLT2 inhibitors, threshold, Type 1 Diabetes

Categories: Nephrology
Tags: SGLT2 inhibitors, threshold, Type 1 Diabetes

Temporal variation of renal function in people with type 2 diabetes mellitus: a retrospective UK Clinical Practice Research Datalink cohort study

April 3rd 2019

Overall, eGFR declined over time, although there was considerable variation between GFR categories and individuals. This highlights the difficulty in prescribing many glucose‐lowering therapies, which require dose adjustment for renal function. The study also emphasizes the importance of regular monitoring of renal impairment in people with T2DM (Diabetes, Obesity and Metabolism)

Categories: Nephrology, News
Tags: eGFR, Type 2 Diabetes

Categories: Nephrology
Tags: eGFR, Type 2 Diabetes

Effect of sodium-glucose cotransporter 2 inhibitor on proximal tubular function and injury in patients with type 2 diabetes: a randomized controlled trial

January 7th 2019

This study indicates that dapagliflozin in T2DM patients can decrease the levels of urinary proximal tubular injury biomarkers, thus highlighting its renoprotective effect. SGLT2 inhibitors could prove useful in treating T2DM by protecting against renal tubular injury and may lead to reduced long-term renal outcomes (Clinical Kidney Journal)

Categories: Nephrology, News
Tags: SGLT2 inhibitors, Type 2 Diabetes

Categories: Nephrology
Tags: SGLT2 inhibitors, Type 2 Diabetes

Comparative efficacy of individual renin–angiotensin system inhibitors on major renal outcomes in diabetic kidney disease: a network meta-analysis

November 5th 2018

Based on the available evidence, individual ACEIs and ARBs at goal doses appeared to have no or little differences in their effect on major renal outcomes (Nephrology Dialysis Transplantation)

Categories: Nephrology, News
Tags: ACEI, ARB

Categories: Nephrology
Tags: ACEI, ARB

Association of microalbuminuria with diabetes is stronger in people with prehypertension compared to those with ideal blood pressure

July 4th 2018

Findings revealed a statistically significant link between diabetes and microalbuminuria only in prehypertensive subjects. They also found that the interaction between perhypertension and diabetes conferred risk for MA (Nephrology)

Categories: Nephrology, News
Tags: microalbuminuria

Categories: Nephrology
Tags: microalbuminuria

Renal glucose metabolism in normal physiological conditions and in diabetes

August 8th 2017

The kidney plays a direct and significant role in glucose homeostasis via gluconeogenesis, glucose uptake and utilization, and glucose reabsorption from glomerular filtrate …  (Diabetes Research and Clinical Practice)

Categories: Nephrology, News
Tags: metabolism, renal

Categories: Nephrology
Tags: metabolism, renal

Urinary albumin excretion with sitagliptin compared to sulfonylurea as add on to metformin in type 2 diabetes patients with albuminuria: a real-world evidence study

May 18th 2016

Our results suggest that both sitagliptin and SU reduce albuminuria as an add-on therapy to metformin, but that sitagliptin may provide greater reductions in albuminuria independent of glycemic control when compared to SU. Larger population studies are required to further explore this (Diabetes and Its Complications)

Categories: Nephrology, News
Tags: albuminuria, sitagliptin, sulfonylureas, Type 2 Diabetes

Categories: Nephrology
Tags: albuminuria, sitagliptin, sulfonylureas, Type 2 Diabetes

Sodium Glucose Cotransporter 2 Inhibition in the Diabetic Kidney

February 16th 2016

The findings expand and refine our understanding of SGLT2 and its inhibition, have relevance for clinical practice, and will help interpret ongoing clinical trials on the long-term safety and cardiovascular effects of SGLT2 inhibitors (Medscape) – Registration required

Categories: Nephrology, News
Tags: SGLT2 inhibitor

Categories: Nephrology
Tags: SGLT2 inhibitor

The renal threshold for glucose re-absorption predicts diabetes improvement by sodium glucose co-transporter 2 inhibitor therapy

January 8th 2016

These findings indicate that patients who have higher renal threshold for glucose re-absorption can be expected to more effectively respond to SGLT2 inhibitor therapy in terms of lowering HbA1c level (Journal of Diabetes Investigation)

Categories: Nephrology, News
Tags: HbA1c, SGLT2 inhibitor

Categories: Nephrology
Tags: HbA1c, SGLT2 inhibitor

Urinary Potassium Excretion and Renal and Cardiovascular Complications in Patients with Type 2 Diabetes and Normal Renal Function

November 13th 2015

Higher urinary potassium excretion was associated with the slower decline of renal function and the lower incidence of cardiovascular complications in type 2 diabetic patients with normal renal function. Interventional trials are necessary to determine whether increasing dietary potassium is beneficial (Clinical Journal of the American Society of Nephrology)

Categories: Nephrology, News
Tags: potassium, Type 2 Diabetes

Categories: Nephrology
Tags: potassium, Type 2 Diabetes

Diabetic Kidney Disease: Pathophysiology and Therapeutic Targets

May 1st 2015

The purpose of this review is to describe the current understanding of how the hemodynamic, metabolic, inflammatory, and alternative pathways are all entangled in pathogenesis of DKD and detail the various therapeutic targets that may one day play a role in quelling this epidemic (Journal of Diabetes Research)

Categories: Nephrology, News
Tags: DKD

Categories: Nephrology
Tags: DKD
  • 1
  • 2
  • 3
  • 4
  • Next Page »

Subscribe

subscribe-iconFREE weekly updates by email Please CLICK HERE

Gold Sponsors

AstraZenecaNovo NordiskNapp DiabetesBoehringer Ingelheim

Silver Sponsors

About Ascensia Diabetes CareWelsh Endocrinology and Diabetes Society (WEDS)Abbott Diabetes Care

FUNDING NOTICE

The Glycosmedia website and newsletter has been made possible with funding support from our sponsors. None of our sponsors have control over the content of the website, newsletter, apps, Twitter feed or RSS newsfeed.

For information about sponsorship and advertising please contact our editor-in-chief Jim Young jim@glycosmedia.com

Advertisers

CRC Press

The organisations advertising in this section do not have any input into, or editorial control over the content of this website.

Categories

  • Audits
  • Bariatric
  • Biochemistry
  • Cardiovascular
  • Devices
  • Diagnosis
  • Diet
  • Education
  • Epidemiology
  • Genetics
  • Gestational
  • Guidance
  • Guidelines
  • Hepatology
  • Hypertension
  • Immunology
  • Management
  • Media
  • Medication
  • Meetings
  • Monitoring
  • Nephrology
  • Neuropathy
  • Nephropathy
  • Obesity
  • Ophthalmology
  • Paediatrics
  • Pathology
  • Pharma
  • Pharmacology
  • Physiology
  • Podiatry
  • Prediabetes
  • Prevalence
  • Prevention
  • Psychological
  • Reports
  • Research
  • Screening
  • Sponsorship
  • Technology
  • Testing
  • Transplantation
  • Treatment
  • Wound Care

To see all articles associated with a category just click on the category name.

Popular Tags

ADA BMI canagliflozin CGM CKD closed-loop COVID-19 dapagliflozin DPP4 DPP4 inhibitors Empagliflozin exenatide GLP-1 RA GLP-1RA GLP1 glycaemic control HbA1c heart failure hyperglycemia hypoglycemia incretin insulin insulin pump Insulin resistance Ketoacidosis liraglutide metformin microvascular mortality NAFLD NICE pioglitazone retinopathy semaglutide SGLT2 inhibitors sitagliptin statin sulfonylureas Type 1 Diabetes Type 2 Diabetes

To see all articles associated with a tag just click on the tag name.

Complete list of Tags ››

Join us on Facebook

Join us on Facebook

Please share Glycosmedia:

Follow us on Twitter

My Tweets

mobileGlycosmedia is also available as an App:

For iPhone and iPad | For Android devices


Sponsorship and Advertising

For information about sponsorship and advertising please contact our editor-in-chief Jim Young jim@glycosmedia.com

Copyright © 2022 Glycosmedia Partnership