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Diabetes News

Category: Ophthalmology


Diabetic Retinopathy as a Predictor of Angiographic Coronary Atherosclerosis Severity in Patients with Type 2 Diabetes Mellitus

May 10th 2022

The presence and degree of DR are independent predictors of severe coronary atherosclerosis. Therefore, when evaluating whether a patient with T2DM is at high risk for CAD, the DR degree should be taken into consideration (Metabolic Syndrome and Obesity)

Categories: Cardiovascular, News, Ophthalmology
Tags: atherosclerosis, retinopathy, Type 2 Diabetes

Categories: Cardiovascular, Ophthalmology
Tags: atherosclerosis, retinopathy, Type 2 Diabetes

Pre-existing diabetic retinopathy as a prognostic factor for covid-19 outcomes amongst people with diabetes: a systematic review

April 5th 2022

The current literature suggests an independent association between DR and poorer COVID-19 prognosis in patients with DM after controlling for key variables such as age (Diabetes Research and Clinical Practice)

Categories: News, Ophthalmology, Pathology
Tags: COVID-19, retinopathy

Categories: Ophthalmology, Pathology
Tags: COVID-19, retinopathy

Relationship Between Muscle Cramps and Diabetic Retinopathy in Patients with Type 2 Diabetes

March 15th 2022

Muscle cramps occur frequently in diabetes and are correlated with diabetic retinopathy and albumin. Patients with PDR exhibited a higher frequency, severity, and longer duration relative to those with NPDR or without DR (Metabolic Syndrome and Obesity)

Categories: News, Ophthalmology
Tags: cramps, retinopathy, Type 2 Diabetes

Categories: Ophthalmology
Tags: cramps, retinopathy, Type 2 Diabetes

Suprachoroidal versus Intravitreal Triamcinolone Acetonide for the Treatment of Diabetic Macular Edema

March 10th 2022

SCTA is a safe and effective route for the treatment of DME, which has comparable effects to IVTA, and may even last longer (Clinical Ophthalmology)

Categories: News, Ophthalmology
Tags: DME, Triamcinolone Acetonide

Categories: Ophthalmology
Tags: DME, Triamcinolone Acetonide

Oxurion Announces New Data on THR-149 Phase 2 Clinical Trial (“KALAHARI”) in DME

February 14th 2022

Post-hoc analysis reveals >9 letter gain in mean BCVA that was maintained for the remaining four months of the trial after the last THR-149 injection with no rescue treatment required
These gains were seen in patients that are part of the 40-50% of DME patients that suboptimally respond to standard of care anti-VEGF therapy (Oxurion)

Categories: Medication, News, Ophthalmology
Tags: DME

Categories: Medication, Ophthalmology
Tags: DME

Metformin and risk of age-related macular degeneration in individuals with type 2 diabetes: a retrospective cohort study

February 14th 2022

We found no evidence that metformin was associated with risk of AMD in primary care patients requiring treatment for type 2 diabetes (BMJ)

Categories: Medication, News, Ophthalmology
Tags: AMD, Type 2 Diabetes

Categories: Medication, Ophthalmology
Tags: AMD, Type 2 Diabetes

Use of Anthropometric Measures of Obesity to Predict Diabetic Retinopathy in Patients with Type 2 Diabetes in China

September 22nd 2021

WHtR and BMI but not WHR are risk factors for DR in obese patients with T2D. Patients with high WHtR and BMI should be closely monitored to prevent the development of DR (Diabetes, Metabolic Syndrome and Obesity)

Categories: News, Ophthalmology
Tags: DR, retinopathy, Type 2 Diabetes

Categories: Ophthalmology
Tags: DR, retinopathy, Type 2 Diabetes

Association of maternal diabetes during pregnancy with high refractive error in offspring: a nationwide population-based cohort study

August 18th 2021

Our findings suggest that maternal diabetes during pregnancy is associated with an increased risk of high RE in offspring, in particular among those of mothers with diabetic complications (Diabetologia)

Categories: Gestational, News, Ophthalmology
Tags: refractive error

Categories: Gestational, Ophthalmology
Tags: refractive error

Bacterial infections as novel risk factors of severe diabetic retinopathy in individuals with type 1 diabetes

July 22nd 2021

Bacterial infections are associated with an increased risk of incident SDR in type 1 diabetes (British Journal of Ophthalmology)

Categories: News, Ophthalmology
Tags: infection, retinopathy, Type 1 Diabetes

Categories: Ophthalmology
Tags: infection, retinopathy, Type 1 Diabetes

Prospective evaluation of an artificial intelligence-enabled algorithm for automated diabetic retinopathy screening of 30 000 patients

April 22nd 2021

The algorithm demonstrated safe levels of sensitivity for high-risk retinopathy in a real-world screening service, with specificity that could halve the workload for human graders (British Journal of Ophthalmology)

Categories: News, Ophthalmology, Screening
Tags: retinopathy

Categories: Ophthalmology, Screening
Tags: retinopathy

Incidence of sight threatening diabetic retinopathy in an established urban screening programme: an 11‐year cohort study

April 9th 2021

In an established screening programme with a stable population screen positive rates show a consistent fall over time to a low level. Of those who are screen positive, fewer than 50% are screen positive for DR. Most are due to sight threatening maculopathy (Diabetic Medicine)

Categories: News, Ophthalmology, Screening
Tags: retinopathy

Categories: Ophthalmology, Screening
Tags: retinopathy

The contribution of the English NHS Diabetic Eye Screening Programme to reductions in diabetes-related blindness, comparisons within Europe, and future challenges

April 8th 2021

Current plans for NHS DESP include extension of screening intervals in low-risk groups and the introduction of optical coherence tomography as a second line of screening for those with screen positive maculopathy with two dimensional markers. Future challenges include the introduction of automated analysis for grading and new camera technologies (Acta Diabetologica)

Categories: News, Ophthalmology, Screening
Tags: NHS

Categories: Ophthalmology, Screening
Tags: NHS

Abnormal N-Glycosylation of Human Lens Epithelial Cells in Type-2 Diabetes May Contribute to Cataract Progression

April 1st 2021

These results suggest that over-expression of N-glycosidically linked human type 1 cytokeratin may induce capsule disruption and affect selective permeability, allowing the entry of different molecules to the lens that facilitate cataract progression (Clinical Ophthalmology)

Categories: News, Ophthalmology
Tags: cataract, Type 2 Diabetes

Categories: Ophthalmology
Tags: cataract, Type 2 Diabetes

The Role of SGLT2 Inhibitor on the Treatment of Diabetic Retinopathy

November 13th 2020

Recent studies have found that SGLT2 is also expressed in the human retina. Now, the prevention and treatment of diabetic retinopathy with SGLT2i while reducing blood sugar has become a new research field. Hence, this article reviewed the recent therapeutic and research progress of SGLT2 in the treatment of diabetic retinopathy (Journal of Diabetes Research)

Categories: News, Ophthalmology
Tags: retinopathy, SGLT2 inhibitors

Categories: Ophthalmology
Tags: retinopathy, SGLT2 inhibitors

Different retinopathy phenotypes in type 2 diabetes predict retinopathy progression

October 7th 2020

Different DR phenotypes in type 2 diabetes show different risks of retinopathy progression. Phenotype C is associated with increased HbA1c values and presents a higher risk of a 2-or-more-step worsening of the ETDRS severity score (Acta Diabetologica)

Categories: News, Ophthalmology
Tags: phenotypes, retinopathy, Type 2 Diabetes

Categories: Ophthalmology
Tags: phenotypes, retinopathy, Type 2 Diabetes

Patrolling Monocytes Are Recruited and Activated By Diabetes To Protect Retinal Microvessels

September 14th 2020

Thus, after short diabetes duration, PMo are the cells preferentially recruited to the retinal vessels and protect vessels from diabetic damage (Diabetes)

Categories: News, Ophthalmology
Tags: monocytes

Categories: Ophthalmology
Tags: monocytes

The unique association between the level of peripheral blood monocytes and the prevalence of diabetic retinopathy: a cross-sectional study

June 24th 2020

Decreased peripheral blood monocyte levels were associated with increased odds of DR after adjusting for potential confounders in diabetic adults. However, causation remains to be demonstrated(Journal of Translational Medicine)

Categories: News, Ophthalmology
Tags: monocytes

Categories: Ophthalmology
Tags: monocytes

Eye care providers’ emerging roles in early detection of diabetes and management of diabetic changes to the ocular surface: a review

April 22nd 2020

Recent ophthalmic research has identified multiple subclinical and clinical changes that occur in the anterior segment of the eye with metabolic disease (BMJ)

Categories: News, Ophthalmology, Screening
Tags: opticians

Categories: Ophthalmology, Screening
Tags: opticians

Retinopathy develops at similar glucose levels but higher HbA1c levels in people with black African ancestry compared to white European ancestry: evidence for the need to individualize HbA1c interpretation

March 4th 2020

Since retinopathy occurs at higher HbA1c levels in black people for a given level of average plasma glucose, strategies may be needed to individualize the interpretation of HbA1c measurements (Diabetic Medicine)

Categories: News, Ophthalmology
Tags: HbA1c

Categories: Ophthalmology
Tags: HbA1c

How to perform better intervention to prevent and control diabetic retinopathy among patients with type 2 diabetes: A meta-analysis of randomized controlled trials

September 25th 2019

We found that multifactorial interventions can significantly reduce the risk of developing DR and its progression among patients with type 2 diabetes. More importantly, we found all these multifactorial interventions contained individualization of targets and communication between health professionals and patients, suggesting ophthalmologists and diabetes health professionals should work together with patients to set more individualized targets while taking into account multiple factors so as to achieve optimal effect in DR prevention and control (Diabetes Research and Clinical Practice)

Categories: News, Ophthalmology
Tags: Type 2 Diabetes

Categories: Ophthalmology
Tags: Type 2 Diabetes
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