Youth with type 2 diabetes exhibit complications sooner than youth with type 1 diabetes. Younger age at diagnosis is potentially protective, and glycemic control is an important modifiable risk factor. The unexpected adverse association between RAAS inhibitor use and outcome is likely a confounder by indication; however, further evaluation in young people is warranted (Diabetes Care)
Diabetes News
Category: Paediatrics
Neuroanatomical correlates of dysglycemia in children T1D
Early onset T1D affects regions of the brain that are associated with typical cognitive development (Diabetes)
Dextrose gel for neonatal hypoglycaemia
Treatment with dextrose gel is inexpensive and simple to administer. Dextrose gel should be considered for first-line treatment to manage hypoglycaemia in late preterm and term babies in the first 48 h after birth (The Lancet)
Children in TEDDY study diagnosed T1D at an early stage
Close follow-up of children with genetic risk enables early detection of T1D. Risk factors for rapid development of diabetes in this young population were first-degree relatives status and autoantibodies to glutamic acid decarboxylase (GADA), insulinoma-associated protein 2 (IA-2) and insulin (IAA) (Pediatric Diabetes)
Identifying challenges of living with T1D: child and youth perspectives
It is important for nurses to discuss challenges, understand perspectives of this age group, listen to their concerns, work with them to develop strategies promoting health, minimise complications, reduce or eliminate feeling different or alone and assist parents’ efforts to be supportive (Journal of Clinical Nursing)
Prevalence of ketoacidosis at diagnosis of childhood onset T1D in Wales
Over 20 years in Wales there has been no change in the proportion of children with Type 1 diabetes initially presenting with ketoacidosis. This presentation occurs in a higher proportion of new cases aged under 5 years. Publicity to increase awareness did not reduce the proportion with ketoacidosis at diagnosis in Wales (Diabetic Medicine)
Diabetes – the teenage years
The adolescent and young adult years are difficult enough for a young person to handle, the additional burden of managing diabetes making this even harder.
T1D pre-school – long-term metabolic control, autoimmunity & complications
For children diagnosed with Type 1 diabetes aged under 6 years, good metabolic control was achievable until age 10 years, after which it deteriorated. Higher HbA1c levels observed in children diagnosed before the age of 6 years were associated with longer duration of disease (Diabetic Medicine)
Serum vitamin D levels are lower in Australian children with t1D
Children with T1DM have lower 25OHD than controls, even in an environment of abundant sunlight. Whether low vitamin D is a risk factor or consequence of T1DM is unknown (Pediatric Diabetes)
Determinants of Insulin Resistance in Infants at Age 1 Year – Impact of gestational diabetes mellitus
In the 1st year of life, weight gain in infants born to women with GDM is associated with insulin resistance, unlike in their peers (Diabetes Care)
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