Compared with practices with no nurse(s) employed, the quality of diabetes management was generally higher in terms of that HbA1c was measured according to the guidelines in a larger proportion of the diabetes population and the proportion of patients with an HbA1c level =8% was lower in practices with well-implemented nurse-led type 2 diabetes consultations (Primary Care Diabetes)
Diabetes News
Glycosmedia is dedicated to bringing free, non-promotional, editorially independent news to a global audience about developments in diabetes, and is primarily aimed at health professionals.
Serum vitamin D levels are lower in Australian children with t1D
Children with T1DM have lower 25OHD than controls, even in an environment of abundant sunlight. Whether low vitamin D is a risk factor or consequence of T1DM is unknown (Pediatric Diabetes)
Blood Glucose Control in Type 1 Diabetes With a Bihormonal Bionic Endocrine Pancreas
A bihormonal bionic endocrine pancreas achieved excellent glycemic control with minimal hypoglycemia over the course of 2 days of continuous use despite high-carbohydrate meals and exercise. A trial testing a wearable version of the system under free-living conditions is justified (Diabetes Care)
Genes for type 2 diabetes are they worth it?
A recent publication reported the identification of another ten genes which may predispose to type 2 diabetes (T2DM), bringing the current total to around fifty. However, the impact of these genetic studies from a clinical perspective remains minimal. Forty years after the discovery of the first genes involved in diabetes susceptibility, should we be querying the value of expensive ‘factory floor’ genetics?
Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials
Parents report moderate willingness to enroll children in T1DCTs. Willingness is diminished by common trial methodologies. Although most parents recalled receiving trial-related information, significantly fewer recalled being asked to participate. Efforts to optimize effective communication around identified areas of parental concern may increase T1DCT participation (PLoS ONE)
Diabetes, glucose control, glucose lowering medications, and cancer risk: A 10-year population-based historical cohort
The current study will undertake various means to deal with the challenges posed by recent investigations, including comparison to a large population of individuals without diabetes in a nationwide population, and accessing a large number of potentially confounding factors and data on cancer screening BMC Cancer)
Screening for pre-diabetes to predict future diabetes using various cut-off points for HbA1c and impaired fasting glucose
The combination of HbA1c 39–46 mmol/mol (5.7–6.4%) and fasting plasma glucose 5.6–6.9 mmol/l would have the best performance in reducing the likelihood of missing future cases of diabetes. Identifying pre-diabetic individuals who strictly fulfil HbA1c 42–46 mmol/mol (6.0–6.4%) and fasting plasma glucose 6.1–6.9 mmol/l would predict definite progression to diabetes (Diabetic Medicine)
Novel therapy for Type 1 diabetes – autologous hematopoietic stem cell transplantation
Here we discuss the therapeutic efficacy and the potential mechanisms underlying the action of HSCT and other prospectives in the clinical management of type 1 diabetes (Journal of Diabetes)
Coming Next: Using an App as Prescribed
Medical professionals and entrepreneurs want to use similar approaches to dealing with chronic ailments like diabetes or heart disease (New York Times)
A bill to amend the Public Health Service Act to foster more effective implementation and coordination of clinical care for people with pre-diabetes and diabetes
To established within the Department of Health and Human Services the National Diabetes Clinical Care Commission to evaluate and make recommendations regarding better coordination and leveraging of programs within the Department of Health and Human Services and other Federal agencies that relate in any way to supporting appropriate clinical care (such as any interactions between physicians and other health care providers and their patients with pre-diabetes and diabetes where care is rendered for the management of their pre-diabetes or diabetes or its complications) for people with pre-diabetes and diabetes (US Senate)
Glymera for the Treatment of Uncontrolled Type 2 Diabetes
PhaseBio Pharmaceuticals Initiates a Multicenter, Randomized Placebo and Active Comparator Controlled Phase 2b Trial to Evaluate use of Glymera for the Treatment of Uncontrolled Type 2 Diabetes (PhaseBio)
Bariatric Surgery and Prevention of Type 2 Diabetes in Swedish Obese Subjects
Bariatric surgery appears to be markedly more efficient than usual care in the prevention of type 2 diabetes in obese persons (New England Journal of Medicine)
Comparative Effectiveness and Safety of Methods of Insulin Delivery and Glucose Monitoring for Diabetes Mellitus
Continuous subcutaneous insulin infusion and multiple daily injections have similar effects on glycemic control and hypoglycemia, except continuous subcutaneous insulin infusion has a favorable effect on glycemic control in adults with type 1 diabetes mellitus (Annals of Internal Medicine)
Intensive versus conventional glucose control in critically ill patients: A meta-analysis of randomized controlled trials
This meta-analysis found that intensive glucose control in critically ill adults did not reduce mortality but is associated with a significantly increased risk of hypoglycemia (European Journal of Internal Medicine)
Distribution of hydrogen sulfide (H2S)-producing enzymes and the roles of the H2S donor sodium hydrosulfide in diabetic nephropathy
These findings suggest that CSE expression in the proximal tubules may also regulate tubulointerstitial microcirculation via H2S production. H2S may represent a target of treatment to prevent progression of ischemic injury in diabetic nephropathy (Clinical and Experimental Nephrology)
Infant antibiotic exposures and early-life body mass
Exposure to antibiotics during the first 6 months of life is associated with consistent increases in body mass from 10 to 38 months (Nature)
The role of the care model in modifying prognosis in diabetes
The sharing of care pathways between primary care providers and diabetes teams is likely to be the best and most affordable solution in the complex management of this chronic condition (Nutrition, Metabolism & Cardiovascular Diseases)
Towards Automatic Diabetes Case Detection and ABCS Protocol Compliance Assessment
The presented approach accurately identified diabetes in medical discharge summaries and showed promise with regards to assessment of protocol compliance and high risk factors. Utilizing free-text analytic techniques on medical text can complement clinical-public health decision support by identifying cases and high risk factors (Clinical Medicine & Research)
Randomised controlled trial of an automated, interactive telephone intervention to improve type 2 diabetes management
These analyses indicate the efficacy of the Australian TLC Diabetes program with clinically significant post-intervention improvements in both glycaemic control and mental HRQL (BMC Public Health)
Blood pressure control among patients with hypertension and newly diagnosed diabetes
We found an increase in blood pressure control in the 6 months following initiation of diabetes treatment. However, overall blood pressure control remained suboptimal and with no further improvement over the next 18 months (Diabetic Medicine)
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