Generally, the use of SGLT2i was consistently associated with decreased risk of renal events in all prespecified eGFR and albuminuria spectrums, even in patients with substantial renal impairment (Acta Diabetologica)
Diabetes News
Glycosmedia is dedicated to bringing free, non-promotional, editorially independent news to a global audience about developments in diabetes, and is primarily aimed at health professionals.
Beraprost Sodium Delays the Decline of Glomerular Filtration Rate in Patients with Diabetic Nephropathy: A Retrospective Study
Combination of conventional treatment and BPS therapy delays the decline of eGFR in patients with DN in the long term (Diabetes Therapy)
Importance of beta cell mass for glycaemic control in people with type 1 diabetes
Our data show higher beta cell mass in people with type 1 diabetes and LGV than in those with HGV, independent of beta cell function (Diabetologia)
The relationship between islet autoantibody status and the genetic risk of type 1 diabetes in adult-onset type 1 diabetes
The inclusion of non-autoimmune diabetes is the most likely explanation for the observed lower rate of autoantibody positivity in clinician-diagnosed adult-onset type 1 diabetes. Our data support the utility of islet autoantibody measurement in clinician-suspected adult-onset type 1 diabetes in routine clinical practice (Diabetologia)
Global trends in the incidence of hospital admissions for diabetes-related foot disease and amputations: a review of national rates in the 21st century
These findings suggest that hospital admission rates for all DFD conditions are considerably higher than those for amputations alone and, thus, the more common practice of reporting admission rates only for amputations may substantially underestimate the burden of DFD (Diabetologia)
The impact of population-level HbA1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis
Our population-based study shows that HbA1c screening in adults aged 40–70 years can reduce the time to diabetes diagnosis by a median of 2.2 years compared with routine clinical care (Diabetologia)
High-density lipoprotein subclasses and cardiovascular disease and mortality in type 2 diabetes: analysis from the Hong Kong Diabetes Biobank
Small HDL-P were inversely associated with incident CVD and all-cause mortality and improved risk stratification for adverse outcomes in people with T2D. HDL-P may be used as markers for residual risk in people with T2D (Cardiovascular Diabetology)
Addressing health inequalities in diabetes through research: Recommendations from Diabetes UK’s 2022 health inequalities in diabetes workshop
This position statement outlines recommendations to address the urgent need to tackle health inequalities in diabetes through research and calls on the diabetes research community to act upon these recommendations to ensure future research works to eliminate unfair and avoidable disparities in health (Diabetic Medicine)
Introduction and Methodology: Standards of Care in Diabetes—2023
The American Diabetes Association (ADA) “Standards of Care in Diabetes,” referred to here as the Standards of Care, is intended to provide clinicians, researchers, policy makers, and other interested individuals with the components of diabetes care, general treatment goals, and tools to evaluate the quality of care (Diabetes Care)
Does the design of the NHS Low Calorie Diet Programme have fidelity to the programme specification?
A documentary review of service parameters and behaviour change content in a Type 2 Diabetes intervention (Diabetic Medicine)
Pre-admission use of sodium glucose transporter-2 inhibitor (SGLT-2i) may significantly improves Covid-19 outcomes in patients with diabetes
This study suggests that SGLT-2i as glucose lowering treatment in patients with diabetes has a positive effect on Covid-19 outcomes, therefore can be considered as an antidiabetic drug of choice, especially during the Covid-19 pandemic (Diabetes Research and Clinical Practice)
Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study
Identified proteins may represent viable intervention or pharmacological targets to prevent, reverse or slow type 2 diabetes progression, and further research is needed to pursue these targets (Diabetologia)
Continuous glucose monitoring and metrics for clinical trials: an international consensus statement
These recommendations have been endorsed by the American Association of Clinical Endocrinologists, the American Diabetes Association, the Association of Diabetes Care and Education Specialists, DiabetesIndia, the European Association for the Study of Diabetes, the International Society for Pediatric and Adolescent Diabetes, the Japanese Diabetes Society, and the Juvenile Diabetes Research Foundation (The Lancet Diabetes & Endocrinology)
ISPAD Clinical Practice Consensus Guidelines 2022: Psychological care of children, adolescents and young adults with diabetes
Being diagnosed with diabetes in childhood or adolescence can interfere with the normative developmental changes and interact with psychological and social factors in youth and their families. Integrated, collaborative care is therefore necessary (Pediatric Diabetes)
Microvascular Disease and the Pathogenesis of Heart Failure in Diabetes: A Tiny Piece of the Tricky Puzzle
Development of HF in diabetes is a complex and multifactorial process that involves different mechanisms (Diabetes Care)
Observational Evaluations of Disease Management Programs for Diabetes: The Proof Is in the Concept
Despite the introduction of multiple novel therapeutics over the past two decades, rates of control in type 2 diabetes (T2D) and its comorbidities remain suboptimal and may have even declined (Diabetic Care)
‘No one ever asks about something that actually is relevant to my life’
A qualitative study of diabetes and diabetes care experiences of young women with type 2 diabetes during their reproductive years (Diabetic Medicine)
Body mass index versus surrogate measures of central adiposity as independent predictors of mortality in type 2 diabetes
The present analysis aimed at assessing the independent association of BMI versus surrogate measures of central adiposity (including both WHtR and ABSI) with death from any cause in the large cohort of well-characterized individuals with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study, which allows accounting for several potential sources of bias (Cardiovascular Diabetology)
Diabetes high impact interventions
An evidence based and quality assured programme that aims to support the person and their family members and carers in developing attitudes, beliefs, knowledge and skills to self-manage diabetes and reduce their chances of deterioration or exacerbation (NHS England)
Longitudinal changes in vitamin D concentrations and the association with type 2 diabetes mellitus: the Tromsø Study
25(OH)D concentrations seem to be affected by disease progression and type 2 diabetes diagnosis (Acta Diabetologica)
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