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Diabetes News

Category: Pathology


Adiponectin and All-Cause Mortality in Elderly People With Type 2 Diabetes

July 12th 2012

Contrary to our hypothesis, higher adiponectin level was related to higher all-cause mortality. This association was not explained by confounding by other characteristics, including medications or preceding weight loss (Diabetes Care)

Categories: News, Pathology

Categories: Pathology

Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration

June 27th 2012

Increased inflammation, expression of MMP-9, PTP1B, and aberrant growth factor levels are the main factors associated with failure to heal DFUs. Targeting these factors may prove helpful in the management of DFUs (Diabetes)

Categories: News, Pathology

Categories: Pathology

Early Loss of the Glucagon Response to Hypoglycemia in Adolescents With Type 1 Diabetes

June 26th 2012

The glucagon response to hypoglycemia in adolescents with type 1 diabetes is influenced by the duration of diabetes and can be lost early in the course of the disease (Diabetes Care)

Categories: News, Pathology

Categories: Pathology

Association of Prediabetes and Diabetes With Stroke Symptoms

June 21st 2012

The REasons for Geographic And Racial Differences in Stroke (REGARDS) study – In this population-based study, almost one in four individuals with diabetes reported stroke symptoms, which suggests that screening for stroke symptoms in diabetes may be warranted (Diabetes Care)

Categories: News, Pathology

Categories: Pathology

Female reproduction and type 1 diabetes: from mechanisms to clinical findings

June 19th 2012

Despite improvements in insulin therapy, T1D patients still suffer many reproductive problems that warrant specific diagnoses and therapeutic management. Similar to other states of metabolic stress, T1D represents a challenge to the correct functioning of the reproductive axis (Human Reproduction Update)

Categories: News, Pathology

Categories: Pathology

Postprandial Platelet Activation

June 16th 2012

Our results suggest that postprandial insulin rather than glucose accounts for postprandial platelet activation in T2DM patients (Diabetes)

Categories: News, Pathology

Categories: Pathology

Effect of pre-diabetes on future risk of stroke: meta-analysis

June 15th 2012

Pre-diabetes, defined as impaired glucose tolerance or a combination of impaired fasting glucose and impaired glucose tolerance, may be associated with a higher future risk of stroke, but the relative risks are modest and may reflect underlying confounding (BMJ)

Categories: News, Pathology

Categories: Pathology

Deteriorating tactile sensation in patients with hand syndromes associated with diabetes: A two-year observational study?

June 5th 2012

Light touch perception was reduced in longstanding diabetic hand syndromes. Tactile abnormalities that were detected by clinical examination progressed during a two year period and were related to metabolic control and musculoskeletal diagnosis (Diabetes and Its Complications)

Categories: News, Pathology

Categories: Pathology

Hyperglycemia Increases Muscle Blood Flow and Alters Endothelial Function in Adolescents with Type 1 Diabetes

June 3rd 2012

These results demonstrate that acute hyperglycemia causes vasodilation and alters endothelial function in adolescents with type 1 diabetes and provide insight into the etiology of macrovascular and microvascular complications of type 1 diabetes (Experimental Diabetes Research)

Categories: News, Pathology

Categories: Pathology

Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies

May 30th 2012

The quantitative meta-analysis showed that diabetes was a risk factor for incident dementia (including AD, VD and any dementia) and MCI (Journal of Internal Medicine)

Categories: News, Pathology

Categories: Pathology

Variability in hemoglobin A1c predicts all-cause mortality in patients with type 2 diabetes

May 29th 2012

A retrospective cohort study in type 2 diabetic patients followed for at least 2years between 2003 and 2009 (Journal of Diabetes and Its Complications)

Categories: News, Pathology

Categories: Pathology

The metabolic syndrome and coronary artery disease

May 29th 2012

A structural equation modeling approach suggestive of a common underlying pathophysiology (Metabolism – Clinical and Experimental)

Categories: News, Pathology

Categories: Pathology

Diabetes Differentially Affects Depression and Self-Rated Health by Age in the U.S.

May 28th 2012

Diabetes differentially affects self-rated overall health and depression by age, with convergence in the oldest age-group with and without diabetes (Diabetes Care)

Categories: News, Pathology

Categories: Pathology

Topiramate-Induced Modulation of Hepatic Molecular Mechanisms: An Aspect for Its Anti-Insulin Resistant Effect

May 28th 2012

The study proved that insulin-resistance has an effect on hepatic molecular level and that the topiramate-mediated insulin sensitivity is ensued partly by modulation of hepatic insulin receptor isoforms, activation of tyrosine kinase, induction of GLUT2 and elevation of adiponectin receptors, as well as their ligand, adiponectin, besides its known improving effect on glucose tolerance and lipid homeostasis (PLoS ONE)

Categories: News, Pathology

Categories: Pathology

Abnormal expression and function of Dectin-1 receptor in type 2 diabetes mellitus patients with poor glycemic control (HbA1c>8%)

May 28th 2012

Our data indicate that Dectin-1 may be involved in the abnormal immune responses that are observed in patients with T2D (Metabolism – Clinical and Experimental)

Categories: News, Pathology

Categories: Pathology

Association between carotid intima-media thickness, buccodental status, and glycemic control in pediatric type 1 diabetes

May 28th 2012

More buccodental conditions and carotid intima-media thickness increase appeared in the patients with HbA1c level?>?8.5%, suggesting onset of atherosclerosis. The correlation between buccodental status and HbA1c values may indicate the connection between inflammatory states of atherosclerosis and type 1 diabetes (Pediatric Diabetes)

Categories: News, Pathology

Categories: Pathology

Insulin-Like Growth Factor Axis and Risk of Type 2 Diabetes in Women

May 28th 2012

This prospective study found strong associations of incident diabetes with baseline levels of three IGFBPs and free IGF-I, consistent with hypotheses that the IGF axis might influence diabetes risk (Diabetes)

Categories: News, Pathology

Categories: Pathology
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