Contrary to our hypothesis, higher adiponectin level was related to higher all-cause mortality. This association was not explained by confounding by other characteristics, including medications or preceding weight loss (Diabetes Care)
Diabetes News
Category: Pathology
Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration
Increased inflammation, expression of MMP-9, PTP1B, and aberrant growth factor levels are the main factors associated with failure to heal DFUs. Targeting these factors may prove helpful in the management of DFUs (Diabetes)
Early Loss of the Glucagon Response to Hypoglycemia in Adolescents With Type 1 Diabetes
The glucagon response to hypoglycemia in adolescents with type 1 diabetes is influenced by the duration of diabetes and can be lost early in the course of the disease (Diabetes Care)
Association of Prediabetes and Diabetes With Stroke Symptoms
The REasons for Geographic And Racial Differences in Stroke (REGARDS) study – In this population-based study, almost one in four individuals with diabetes reported stroke symptoms, which suggests that screening for stroke symptoms in diabetes may be warranted (Diabetes Care)
Female reproduction and type 1 diabetes: from mechanisms to clinical findings
Despite improvements in insulin therapy, T1D patients still suffer many reproductive problems that warrant specific diagnoses and therapeutic management. Similar to other states of metabolic stress, T1D represents a challenge to the correct functioning of the reproductive axis (Human Reproduction Update)
Postprandial Platelet Activation
Our results suggest that postprandial insulin rather than glucose accounts for postprandial platelet activation in T2DM patients (Diabetes)
Effect of pre-diabetes on future risk of stroke: meta-analysis
Pre-diabetes, defined as impaired glucose tolerance or a combination of impaired fasting glucose and impaired glucose tolerance, may be associated with a higher future risk of stroke, but the relative risks are modest and may reflect underlying confounding (BMJ)
Deteriorating tactile sensation in patients with hand syndromes associated with diabetes: A two-year observational study?
Light touch perception was reduced in longstanding diabetic hand syndromes. Tactile abnormalities that were detected by clinical examination progressed during a two year period and were related to metabolic control and musculoskeletal diagnosis (Diabetes and Its Complications)
Hyperglycemia Increases Muscle Blood Flow and Alters Endothelial Function in Adolescents with Type 1 Diabetes
These results demonstrate that acute hyperglycemia causes vasodilation and alters endothelial function in adolescents with type 1 diabetes and provide insight into the etiology of macrovascular and microvascular complications of type 1 diabetes (Experimental Diabetes Research)
Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies
The quantitative meta-analysis showed that diabetes was a risk factor for incident dementia (including AD, VD and any dementia) and MCI (Journal of Internal Medicine)
Variability in hemoglobin A1c predicts all-cause mortality in patients with type 2 diabetes
A retrospective cohort study in type 2 diabetic patients followed for at least 2years between 2003 and 2009 (Journal of Diabetes and Its Complications)
The metabolic syndrome and coronary artery disease
A structural equation modeling approach suggestive of a common underlying pathophysiology (Metabolism – Clinical and Experimental)
Diabetes Differentially Affects Depression and Self-Rated Health by Age in the U.S.
Diabetes differentially affects self-rated overall health and depression by age, with convergence in the oldest age-group with and without diabetes (Diabetes Care)
Topiramate-Induced Modulation of Hepatic Molecular Mechanisms: An Aspect for Its Anti-Insulin Resistant Effect
The study proved that insulin-resistance has an effect on hepatic molecular level and that the topiramate-mediated insulin sensitivity is ensued partly by modulation of hepatic insulin receptor isoforms, activation of tyrosine kinase, induction of GLUT2 and elevation of adiponectin receptors, as well as their ligand, adiponectin, besides its known improving effect on glucose tolerance and lipid homeostasis (PLoS ONE)
Abnormal expression and function of Dectin-1 receptor in type 2 diabetes mellitus patients with poor glycemic control (HbA1c>8%)
Our data indicate that Dectin-1 may be involved in the abnormal immune responses that are observed in patients with T2D (Metabolism – Clinical and Experimental)
Association between carotid intima-media thickness, buccodental status, and glycemic control in pediatric type 1 diabetes
More buccodental conditions and carotid intima-media thickness increase appeared in the patients with HbA1c level?>?8.5%, suggesting onset of atherosclerosis. The correlation between buccodental status and HbA1c values may indicate the connection between inflammatory states of atherosclerosis and type 1 diabetes (Pediatric Diabetes)
Insulin-Like Growth Factor Axis and Risk of Type 2 Diabetes in Women
This prospective study found strong associations of incident diabetes with baseline levels of three IGFBPs and free IGF-I, consistent with hypotheses that the IGF axis might influence diabetes risk (Diabetes)
- « Previous Page
- 1
- …
- 15
- 16
- 17