Our findings support the effectiveness of a uniquely mobile prediabetes intervention, producing weight loss comparable to studies with high engagement, with potential for scalable population health management (BMJ)
Diabetes News
Category: Prevention
NIHR highlights research that could improve diabetes care and prevention
On the Level – Evidence for Action on Type 2 Diabetes focuses on four areas of support and care: preventing type 2 diabetes in people at risk, identifying people with type 2 diabetes, self-management, and reducing the risk of complications like eye and kidney disease
Associations between Recreational and Commuter Cycling, Changes in Cycling, and Type 2 Diabetes Risk
Commuter and recreational cycling was consistently associated with lower risk of T2D in Danish adults. Our results also provide evidence that late-in-life initiation of or continued engagement in cycling lowers risk of T2D (PLoS Medicine)
Population Approaches to Prevention of Type 2 Diabetes
With the prevalence of Type 2 Diabetes Mellitus (T2DM) continuing to rise in most high-income, low-income, and middle-income countries [1], strategies to stem the emerging pandemic are urgently needed (PLoS Medicine)
Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention
Reflections From a Diabetes Care Editors’ Expert Forum
Lifetime risk of developing impaired glucose metabolism and eventual progression from prediabetes to type 2 diabetes
Impaired glucose metabolism is a substantial burden on population health, and our findings emphasise the need for more effective prevention strategies, which should be implemented as soon in a person’s life as possible. The substantial lifetime risk of prediabetes and diabetes in lean individuals also supports risk factor control in non-obese individuals (The Lancet Diabetes & Endocrinology)
Adherence to NICE guidelines on diabetes prevention in the UK: Effect on patient knowledge and perceived risk
People at high-risk of diabetes are not being informed of their risk status as recommended by NICE guidelines. There is scope for education for health professionals and the public (Primary Care Diabetes)
US initiative for prediabetes
Health officials in the USA want physicians to help to reduce diabetes by asking at-risk patients to join diabetes prevention programmes. Susan Jaffe reports from Washington, DC (The Lancet Diabetes & Endocrinology)
Vaccines for the prevention of seasonal influenza in patients with diabetes: systematic review and meta-analysis
Due to strong residual confounding in most of the identified studies, the available evidence is insufficient to determine the magnitude of benefit that diabetic people derive from seasonal influenza vaccination. Adequately powered randomized controlled trials or quasi-experimental studies using laboratory-confirmed influenza-specific outcomes are urgently needed (BMC Medicine)
The Effect of Medical Nutrition Therapy by a Registered Dietitian Nutritionist in Patients with Prediabetes Participating in a Randomized Controlled Clinical Research Trial
The results demonstrate that individualized medical nutrition therapy is effective in decreasing HbA1c level in patients diagnosed with prediabetes (Journal of the Academy of Nutrition and Dietetics)
Pharmacological interventions for preventing or delaying onset of type 2 diabetes mellitus
Evidence exists that none of the drugs currently available could sustainably lower cumulative diabetes incidence, none has been shown to provide a durable delay in diabetes diagnosis and none has provided a convincing concomitant excess benefit for micro-or macrovascular risk (Diabetes, Obesity and Metabolism)
Preventing type 2 diabetes: population and community-level interventions
Evidence Update October 2014 (NICE)
Effectiveness of chamomile tea on glycemic control and serum lipid profile T2D
Chamomile tea significantly decreased concentration of HbA1C, serum insulin levels, insulin resistance, total cholesterol, triglyceride, and low-density lipoprotein cholesterol compared with control group (Journal of Endocrinological Investigation)
The Effects of a Mediterranean Diet on Need for Diabetes Drugs and Remission of Newly Diagnosed Type 2 Diabetes
In patients with newly diagnosed type 2 diabetes, an LCMD resulted in a greater reduction of HbA1c levels, higher rate of diabetes remission, and delayed need for diabetes medication compared with a low-fat diet (Diabetes Care)
Prevention of type 2 diabetes; a systematic review and meta-analysis of different intervention strategies
These data indicate that several strategies prevent T2DM, making it possible to make a choice for the individual subject (Diabetes, Obesity and Metabolism)
Autonomous exercise game use improves metabolic control and QoL T2D
In this trial a low-threshold intervention with the interactive exercise game Wii Fit Plus was able to motivate T2DM patients to improve physical activity, glucometabolic control and quality of life (BMC Endocrine Disorders)
Restoration of unfolded protein response in pancreatic ß cells protects against T1D
Administration of a chemical ER stress mitigator, tauroursodeoxycholic acid (TUDCA), at the prediabetic stage resulted in a marked reduction of diabetes incidence in the T1D mouse models ( Science Translational Medicine)
Aerobic and Resistance Exercise Training& Cardiorespiratory Fitness
Structured exercise training, especially the AT component, was associated with a greater number of participants moving above established cut points indicative of low CRF. These results have public health and clinical implications for the growing number of patients with type 2 diabetes at high risk for CVD (Diabetes Care)
Improved lifestyle & decreased diabetes risk over 13 yrs – Finnish study
Lifestyle intervention in people at high risk of type 2 diabetes induces sustaining lifestyle change and results in long-term prevention of progression to type 2 diabetes (Diabetologia)
The Application of the Diabetes Prevention Trial–Type 1 Risk Score (DPTRS) for Identifying a Preclinical State of Type 1 Diabetes
A DPTRS threshold of 9.00 identifies individuals who are very highly likely to progress to the conventional diagnosis of T1D within 2 years and, thus, are essentially in a preclinical diabetic state (Diabetes Care)
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