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Diabetes News

Category: Screening


Identifying patients at increased risk of hypoglycaemia in primary care: Development of a machine learning‐based screening tool

February 23rd 2021

Using demographic and medication data, a model for identifying patients at increased risk of hypoglycaemia was developed using machine learning. This model can be used as a tool in primary care to screen for patients with T2D who may need additional attention to prevent or reduce hypoglycaemic events (Diabetes/Metabolism Research and Reviews)

Categories: News, Screening
Tags: hypoglycemia, Type 2 Diabetes

Categories: Screening
Tags: hypoglycemia, Type 2 Diabetes

Comprehensive Psychosocial Screening in a Pediatric Diabetes Clinic

February 19th 2021

Comprehensive psychosocial screening can be effectively implemented as part of routine pediatric diabetes care and can identify adolescents in need of additional supports (Pediatric Diabetes)

Categories: News, Paediatrics, Psychological, Screening
Tags: psychosocial

Categories: Paediatrics, Psychological, Screening
Tags: psychosocial

Potential biomarker in serum for predicting susceptibility to type 2 diabetes mellitus: Free fatty acid 22:6

December 8th 2020

C22:6 can be an independent risk factor for type 2 diabetes mellitus, and it has a great potential to predict the susceptibility to type 2 diabetes mellitus (Journal of Diabetes Investigation)

Categories: News, Screening
Tags: Type 2 Diabetes

Categories: Screening
Tags: Type 2 Diabetes

Angiopoietin-like 2 is a potential biomarker for diabetic foot patients

December 1st 2020

Circulating ANGPTL2 levels are an independent risk factor for DFUs. This suggests that ANGPTL2 may play important roles in the development of DFUs, a possibility that needs to investigated in prospective studies (BMC Endocrine Disorders)

Categories: News, Screening
Tags: angiopoietin-like 2

Categories: Screening
Tags: angiopoietin-like 2

Adaptation of Insulin Clearance to Metabolic Demand is a Key Determinant of Glucose Tolerance

October 20th 2020

The development of IR in obese subjects is associated with decline in MCRI that represents a compensatory response to maintain normal glucose tolerance but is impaired in T2DM individuals (Diabetes)

Categories: News, Screening
Tags: GTT, IR

Categories: Screening
Tags: GTT, IR

Associations of cardiac stress biomarkers with incident type 2 diabetes and changes in glucose metabolism: KORA F4/FF4 study

October 18th 2020

High plasma concentrations of MR-proANP contributed to a lower risk of incident T2D, whereas high plasma concentrations of copeptin were associated with an increased risk of incident prediabetes/T2D (Cardiovascular Diabetology)

Categories: News, Screening
Tags: Type 2 Diabetes

Categories: Screening
Tags: Type 2 Diabetes

Soluble EGFR, a hepatokine, and adipsin, an adipokine, are biomarkers correlated with distinct aspects of insulin resistance in type 2 diabetes subjects

September 30th 2020

Soluble EGFR, a hepatokine, is correlated with insulin resistance in the liver, while adipsin, an adipokine, is associated with adipose insulin resistance (Diabetology & Metabolic Syndrome)

Categories: News, Screening
Tags: Insulin resistance, Type 2 Diabetes

Categories: Screening
Tags: Insulin resistance, Type 2 Diabetes

Triglyceride-glucose index predicts independently type 2 diabetes mellitus risk: A systematic review and meta-analysis of cohort studies

September 14th 2020

TyG index has a positive and significant association with T2D risk, suggesting that the TyG index may become an applicable tool to identify subjects with T2D risk (Primary Care Diabetes)

Categories: News, Screening
Tags: triglyceride, Type 2 Diabetes

Categories: Screening
Tags: triglyceride, Type 2 Diabetes

Autoantibodies against zinc transporter 8 further stratify the autoantibody-defined risk for type 1 diabetes in a general population of schoolchildren and have distinctive isoform binding patterns in different forms of autoimmune diabetes

August 23rd 2020

Zinc transporter 8 autoantibodies are useful markers for prediction of type 1 diabetes in a general population, further stratifying the risk of progression in autoantibody-positive children (Diabetic Medicine)

Categories: News, Screening
Tags: autoantibodies

Categories: Screening
Tags: autoantibodies

Examining if the relationship between BMI and incident type 2 diabetes among middle–older aged adults varies by race/ethnicity: evidence from the Multi‐Ethnic Study of Atherosclerosis (MESA)

August 5th 2020

This study supports including BMI and presence of type 2 diabetes risk factors as action points for clinicians to prioritize which adults aged ≥ 45 years should be screened (Diabetic Medicine)

Categories: News, Screening
Tags: BMI, Type 2 Diabetes

Categories: Screening
Tags: BMI, Type 2 Diabetes

Risk factors for hospitalization in youth with type 1 diabetes: Development and validation of a multivariable prediction model

August 2nd 2020

Our multivariable prediction model identified patients at increased risk of admission in the 12 months following assessment (Pediatric Diabetes)

Categories: News, Screening
Tags: Type 1 Diabetes

Categories: Screening
Tags: Type 1 Diabetes

Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes

July 8th 2020

Our study provides robust histological evidence that a clinical diagnostic model, combining clinical features and biomarkers, could improve diabetes classification. Our study also provides reassurance that a C‐peptide‐based definition of type 1 diabetes is an appropriate surrogate outcome that can be used in large clinical studies where histological definition is impossible (Diabetic Medicine)

Categories: News, Screening
Tags: histology, Type 1 Diabetes

Categories: Screening
Tags: histology, Type 1 Diabetes

Update on clinical screening of maturity-onset diabetes of the young (MODY)

June 9th 2020

The selection of diabetic patients for genetic testing is an ongoing challenge. Metabolic profiling, diabetes onset age, pancreatic antibodies, and C-peptide seem to be useful tools to better select patients for genetic testing (Diabetology & Metabolic Syndrome)

Categories: News, Screening
Tags: MODY

Categories: Screening
Tags: MODY

Population-based screen-detected type 2 diabetes mellitus is associated with less need for insulin therapy after 10 years

April 22nd 2020

Population-based screen-detected type 2 diabetes is associated with less need for insulin after 10 years compared with people diagnosed during care-as-usual. Glycemic control was better after screen detection but on average good in all groups (BMJ)

Categories: News, Screening
Tags: Type 2 Diabetes

Categories: Screening
Tags: Type 2 Diabetes

Eye care providers’ emerging roles in early detection of diabetes and management of diabetic changes to the ocular surface: a review

April 22nd 2020

Recent ophthalmic research has identified multiple subclinical and clinical changes that occur in the anterior segment of the eye with metabolic disease (BMJ)

Categories: News, Ophthalmology, Screening
Tags: opticians

Categories: Ophthalmology, Screening
Tags: opticians

Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort

December 18th 2019

A lifestyle-related lipidomic profile strongly predicts T2DM development beyond current risk factors. Further studies are warranted to test if lifestyle interventions modifying this lipidomic profile can prevent T2DM (Diabetes Care)

Categories: News, Screening
Tags: lipids, Type 2 Diabetes

Categories: Screening
Tags: lipids, Type 2 Diabetes

Predictive models for diabetes mellitus using machine learning techniques

October 16th 2019

The ability of our model to predict patients with Diabetes using some commonly used lab results is high with satisfactory sensitivity. These models can be built into an online computer program to help physicians in predicting patients with future occurrence of diabetes and providing necessary preventive interventions (BMC Endocrine Disorders)

Categories: News, Screening
Tags: AI

Categories: Screening
Tags: AI

The Role of the Autonomic Nervous System on Cardiac Rhythm during the Evolution of Diabetes Mellitus Using Heart Rate Variability as a Biomarker

May 9th 2019

It is possible to avoid the consequences of DM identifying alterations in Sinus Atrial Node previous to its symptomatic appearance. This could be used as an early diagnosis indicator (Journal of Diabetes Research)

Categories: News, Screening
Tags: autonomic

Categories: Screening
Tags: autonomic

Changes in Screening Practices for Prediabetes and Diabetes Since the Recommendation for Hemoglobin A1c Testing

March 20th 2019

As we observed in 2004, rates of screening are high. HbA1c is still used less frequently than glucose for screening but is more likely to result in a clinical diagnosis. Evidence to support guidelines to define the role of random glucose screening, including definition of appropriate cut points and follow-up, is needed (Diabetes Care)

Categories: News, Screening
Tags: HbA1c

Categories: Screening
Tags: HbA1c

Evaluation of the Finnish Diabetes Risk Score as a screening tool for undiagnosed type 2 diabetes and dysglycaemia among early middle-aged adults in a large-scale European cohort

February 21st 2019

FINDRISC can be applied for screening primarily undiagnosed T2DM but also dysglycaemia among vulnerable groups across Europe, considering the use of different cut-offs for each subpopulation  (Diabetes Research and Clinical Practice)

Categories: News, Screening
Tags: dysglycaemia, Type 2 Diabetes

Categories: Screening
Tags: dysglycaemia, Type 2 Diabetes
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