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Diabetes News

Category: Wound Care


How Effective are Nano-Based Dressings in Diabetic Wound Healing? A Comprehensive Review of Literature

May 10th 2022

This review will focus on the effects of diabetes on wound healing, introduce the properties, preparation methods and action mechanism of nanoparticles in wound healing, and describe the effects and application status of various nanoparticle-loaded dressings in diabetes-related chronic wound healing (International Journal of Nanomedicine)

Categories: News, Wound Care
Tags: nanoparticles

Categories: Wound Care
Tags: nanoparticles

Mechanism and application of exosomes in the wound healing process in diabetes mellitus

April 26th 2022

Most of the recent studies are still in the preclinical stage, and the relevant drugs have not been approved for use. In the future, more research are required to determine the scope of application of exosomes and determine the production routes for a large number of clinical uses. Further studies on exosomes may provide a way to treat diabetic wounds in the future (Diabetes Research and Clinical Practice)

Categories: News, Wound Care
Tags: exosomes

Categories: Wound Care
Tags: exosomes

Emerging Roles of Long Non-Coding RNAs in Diabetic Foot Ulcers

June 9th 2021

In this review, we briefly summarize the current knowledge regarding the functional roles and potential mechanisms of reported lncRNAs in regulating DFU (Dove Press)

Categories: News, Wound Care
Tags: RNA

Categories: Wound Care
Tags: RNA

Factors Associated With Key Outcomes in Diabetes Related Foot Disease: A Prospective Observational Study

May 25th 2021

This prospective study supports the ability of the WIfI classification system to predict one year key clinical outcomes in a diabetic population with foot ulcers. It also demonstrated that grip strength may be a useful predictor of wound healing (European Journal of Vascular & Endovascular Surgery)

Categories: News, Wound Care
Tags: prediction, WIfI

Categories: Wound Care
Tags: prediction, WIfI

Effectiveness of fast-track pathway for diabetic foot ulcerations

May 4th 2021

After the FTP implementation, less cases of LR were reported in comparison to ER. ER was an independent predictor of positive outcomes such as healing, healing time, limb salvage, hospitalization, and survival (Acta Diabetologica)

Categories: Management, News, Wound Care
Tags: foot

Categories: Management, Wound Care
Tags: foot

Treatment of chronic diabetic foot ulcers with adipose‐derived stromal vascular fraction cell injections: Safety and evidence of efficacy at 1 year

April 9th 2021

These results indicate that SVF can be safely used to treat chronic DFU, with evidence of efficacy (wound healing) and mechanisms of action that include vascular repair and/or angiogenesis (Stem Cells Translational Medicine)

Categories: News, Wound Care
Tags: DFU, stromal vascular fraction

Categories: Wound Care
Tags: DFU, stromal vascular fraction

The Role of Recombinant Proteins and Growth Factors in the Management of Diabetic Foot Ulcers: A Systematic Review of Randomized Controlled Trials

July 15th 2020

Overall, there is a greater agreement on the effectiveness of EGF to enhance the healing of diabetic ulcers. Nevertheless, extant evidence is lacking for other agents since few trials have been conducted for most of the growth factors and available studies are heterogeneous in their methodologies (Journal of Diabetes Research)

Categories: News, Wound Care
Tags: foot ulcers, growth factors

Categories: Wound Care
Tags: foot ulcers, growth factors

Surgery for the diabetic foot: A key component of care

December 10th 2019

This brief overview from the Association for Diabetic Foot Surgeons describes common conditions best treated by surgical interventions, as well as specific indications (Diabetes/Metabolism Research and Reviews)

Categories: News, Wound Care
Tags: surgery

Categories: Wound Care
Tags: surgery

Unilateral remote temperature monitoring to predict future ulceration for the diabetic foot in remission

August 25th 2019

Given the high incidence of subsequent diabetic foot complications to the sound foot in patients with a history of proximal LEA and patients being treated for a wound, practice of daily temperature monitoring of a single foot has the potential to significantly improve outcomes and reduce resource utilization in this challenging high-risk population (BMJ)

Categories: News, Wound Care
Tags: foot ulceration

Categories: Wound Care
Tags: foot ulceration

Diabetic foot ulcer incidence and survival with improved diabetic foot services: an 18‐year study

June 2nd 2019

Integrated care for the diabetic foot in one National Health Service (NHS) health service area over 18 years was associated with a reduction in first presentations of diabetic foot ulceration, but failed to reduce recurrent ulceration. Cumulative prevalence of all ulcers continues to increase (Diabetic Medicine)

Categories: News, Wound Care
Tags: NHS

Categories: Wound Care
Tags: NHS

Clinical Commissioning Policy: Hyperbaric oxygen therapy for diabetic lower limb ulceration (diabetic foot ulcer) (all ages)

April 16th 2019

NHS England has carefully reviewed the evidence to treat diabetic lower limb ulceration with hyperbaric oxygen therapy. We have concluded that there is not enough evidence to make the treatment available at this time.

Categories: News, Wound Care
Tags: Hyperbaric

Categories: Wound Care
Tags: Hyperbaric

Remission in diabetic foot infections: Duration of antibiotic therapy and other possible associated factors

January 16th 2019

Our analysis found no threshold for the optimal duration or route of administration of antibiotic therapy to prevent recurrences of DFI. These limited data might support possibly shorter treatment duration for patients with DFI (Diabetes, Obesity and Metabolism)

Categories: News, Wound Care
Tags: antibiotic, DFI

Categories: Wound Care
Tags: antibiotic, DFI

Glucagon-like peptide-1 analogue liraglutide facilitates wound healing by activating PI3K/Akt pathway in keratinocytes

October 24th 2018

Our study suggests that liraglutide may be a potential target drug to improve skin ulcer with diabetes through its specific receptor GLP-1 (Diabetes Research and Clinical Practice)

Categories: News, Wound Care
Tags: GLP1

Categories: Wound Care
Tags: GLP1

Markers of Local Inflammation and Bone Resorption in the Acute Diabetic Charcot Foot

August 2nd 2018

We have found an increased A-V flux of IL-6 in the acute diabetic Charcot foot compared to the healthy foot in the same patients (Journal of Diabetes Research)

Categories: News, Wound Care
Tags: Charcot

Categories: Wound Care
Tags: Charcot

Efficacy of Low-Level Light Therapy for Treatment of Diabetic Foot Ulcer

July 18th 2018

LLLT was recognized as a potential method in the comprehensive treatment of DFUs. Further well designed and high-quality studies are required to confirm the role of LLLT in the management of DFUs (Diabetes Research and Clinical Practice)

Categories: Audits, Wound Care
Tags: foot ulcer, light

Skin hydration of the heel with fissure in patients with diabetes: a cross-sectional observational study

June 12th 2018

To prevent heel fissures, moisturizing care should aim at achieving skin hydration of 20%. If skin hydration is <20%, prevention of fissures may warrant not only specialized moisturizing care but also consideration of treatment for tinea pedis (Chronic Wound Care Management and Research)

Categories: News, Wound Care
Tags: heel fissure, moisturizing

Categories: Wound Care
Tags: heel fissure, moisturizing

Topical Epidermal Growth Factor Spray for the Treatment of Chronic Diabetic Foot Ulcers

June 12th 2018

This study confirms that application of spray-applied rhEGF in DFU patients results in faster healing velocity and higher complete healing rate regardless of HbA1c levels (Diabetes Research and Clinical Practice)

Categories: News, Wound Care
Tags: EGF, ulcer

Categories: Wound Care
Tags: EGF, ulcer

Diabetes foot care profiles: annual update, 2018

May 1st 2018

Annual update of indicators in the diabetes foot care profiles (Public Health England)

Categories: News, Wound Care
Tags: foot care

Categories: Wound Care
Tags: foot care

Barriers to foot care in patients with diabetes as identified by healthcare professionals

April 29th 2018

The crucial barrier to diabetic foot care is delay in accessing specialist care. Until this is addressed, care will be less than optimum and amputations will continue (Diabetic Medicine)

Categories: News, Wound Care
Tags: barriers

Categories: Wound Care
Tags: barriers

Current Challenges and Opportunities in the Prevention and Management of Diabetic Foot Ulcers

March 21st 2018

There is strong suggestive evidence to indicate that appropriate changes in the relevant care pathways can result in a prompt improvement in clinical outcomes (Diabetes Care)

Categories: News, Wound Care
Tags: diabetic foot ulcer, ulcer

Categories: Wound Care
Tags: diabetic foot ulcer, ulcer
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