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Diabetes News

Tag: β cells


Roles of FoxM1-driven basal β-cell proliferation in maintenance of β-cell mass and glucose tolerance during adulthood

May 30th 2022

Basal low-level proliferation of β-cells during adulthood is important for maintaining sufficient β-cell mass and good glucose tolerance and β-cell FoxM1 underlies this mechanism. Preserving β-cell FoxM1 activity may prevent impairment of glucose tolerance with advancing age (Journal of Diabetes Investigation)

Categories: News, Pathology
Tags: FoxM1, β cells

Categories: Pathology
Tags: FoxM1, β cells

Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells

April 5th 2018

The findings reveal unique GABAA receptors signaling in human islets β cells that is GABA concentration-dependent, differentially regulated by drugs, modulates insulin secretion and is altered in T2D (EBioMedicine)

Categories: Biochemistry, News
Tags: GABAA, Type 2 Diabetes, β cells

Categories: Biochemistry
Tags: GABAA, Type 2 Diabetes, β cells

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

July 23rd 2016

The present findings provide new insights into the regulation of islet function by individual β cells and the mechanisms that likely target and impair this during type 2 diabetes pathogenesis and treatment (Cell Metabolism)

Categories: News, Pathology
Tags: β cells

Categories: Pathology
Tags: β cells

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