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Diabetes News

Tag: beta cells


Different Analysis of β-Cell Dysfunction as Fasting Glucose Progresses in Obese and Nonobese Newly Diagnosed Type 2 Diabetic Patients

October 28th 2019

During the progression of baseline FBG, β-cell dysfunction and insulin resistance worsened. As FBG increased, increased BMI had a positive influence on β-cell dysfunction in all FBG groups. The independent factors that correlated to EISI differed with the increasing of baseline FBG (Journal of Diabetes Research)

Categories: News, Pathology
Tags: beta cells, Insulin resistance, Type 2 Diabetes

Categories: Pathology
Tags: beta cells, Insulin resistance, Type 2 Diabetes

Sodium-Glucose Cotransporter-2 Inhibition Improves Incretin Sensitivity of Pancreatic β-cells in Patients with Type 2 Diabetes

August 8th 2017

Dapagliflozin improved β-cell responses to incretin hormones as well as glucose during the hyperglycemic clamp in patients with inadequately controlled T2DM (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: beta cells, incretin, SGLT2 inhibitors, Type 2 Diabetes

Categories: Medication
Tags: beta cells, incretin, SGLT2 inhibitors, Type 2 Diabetes

Metformin Prevents Glucotoxicity by Alleviating Oxidative and ER Stress –Induced CD36 Expression in Pancreatic Beta Cells

September 9th 2016

Metformin conferred protection against HG-induced apoptosis of pancreatic beta cells, largely by interfering with ROS production, and inhibited the CD36- mediated free fatty acid influx. This report provides evidence that the inhibition of CD36 may have potential therapeutic effects against hyperglycemia-induced beta cell damage in diabetes (Journal of Diabetes and Its Complications)

Categories: News, Pathology
Tags: Apoptosis, beta cells, metformin

Categories: Pathology
Tags: Apoptosis, beta cells, metformin

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