It is the first-in-class siRNA to lower cholesterol and keep it low with two doses a year (Novartis)
Diabetes News
Tag: cholesterol
Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study
In extended follow-up of obese adults with type 2 diabetes randomized to adding gastric bypass compared with lifestyle and intensive medical management alone, there remained a significantly better composite triple end point in the surgical group at 5 years. However, because the effect size diminished over 5 years, further follow-up is needed to understand the durability of the improvement (JAMA)
Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study
In extended follow-up of obese adults with type 2 diabetes randomized to adding gastric bypass compared with lifestyle and intensive medical management alone, there remained a significantly better composite triple end point in the surgical group at 5 years. However, because the effect size diminished over 5 years, further follow-up is needed to understand the durability of the improvement (JAMA)
The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index
This study showed that women with GDM had significantly increased cholesterol levels, triacylglycerol levels, TG/HDL-C ratios, LDL-C/HDL-C ratios, and fasting glucose levels during early pregnancy. Moreover, early pregnancy cholesterol levels, triacylglycerol levels, TG/HDL-C ratios, LDL-C/HDL-C ratios, and fasting glucose levels were associated with GDM risk (Journal of Diabetes Research)