The AD‐associated protein pattern found in T2D, with basal elevated APP and reduced SNCA, was exaggerated by hypoglycemia with increased APP and decreased SNCA (Diabetes, Obesity and Metabolism)
Diabetes News
Tag: dementia
Oral diabetes medication and risk of dementia in elderly patients with type 2 diabetes
Overall, the use of oral diabetes medication in type 2 diabetes patients significantly decreased the risk of dementia (Diabetes Research and Clinical Practice)
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia
From the evidence available, there is no reason to favour any particular type of diabetic treatment in order to prevent cognitive impairment in people with Type 2 diabetes (Cochrane)
Effects of Pioglitazone on the Incidence of Dementia in Patients with Diabetes
Pioglitazone is a time- and dose-dependent protective factor against dementia in patients with diabetes. The risk of dementia is lower in long-term and high-dose pioglitazone users than in never users of pioglitazone (Journal of Diabetes and Its Complications)
Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia
Individuals with type 2 diabetes are at ∼60% greater risk for the development of dementia compared with those without diabetes. For vascular dementia, but not for nonvascular dementia, the additional risk is greater in women (Diabetes Care)