Glycosmedia

Diabetes News Service

Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use.
To find out more, including how to control cookies, see here: Cookies Policy
  • News
  • Archive
  • Categories & Tags
  • Journal Watch
  • Updates
  • Education
  • Reviews
  • About us ▼
    • About Glycosmedia
    • Editorial Team
    • Frequently asked questions
    • Comments
    • Press Releases
    • Disclaimer
  • Subscribe
  • Contact

Diabetes News

Tag: DPP4 inhibitors


Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial

October 17th 2021

Our study showed that gemigliptin significantly improved the expression of renal tubular injury biomarkers and vascular calcification levels among patients with DKD; however, gemigliptin did not affect renal function or coronary calcification compared with those observed in the control (Journal of Diabetes Research)

Categories: Medication, Nephropathy, News
Tags: biomarkers, CKD, DPP4 inhibitors

Categories: Medication, Nephropathy
Tags: biomarkers, CKD, DPP4 inhibitors

Dipeptidyl peptidase-4 inhibitor and insulin combination treatment in type 2 diabetes and chronic kidney disease: a meta-analysis

October 1st 2021

This study demonstrated the effectiveness and safety of DPP-4 inhibitors bonded with insulin in patients with T2D and CKD, but the protective actions of this cure on kidney and cardiovascular outcomes, as well as the functions of other DPP-4 inhibitors, need to be affirmed by more good-quality RCTs (Journal of Diabetes Investigation)

Categories: Medication, Neuropathy, News
Tags: DPP4 inhibitors, insulin, Type 2 Diabetes

Categories: Medication, Neuropathy
Tags: DPP4 inhibitors, insulin, Type 2 Diabetes

Impact of SGLT2 inhibitors in comparison to DPP4 inhibitors on ascites and death in veterans with cirrhosis on metformin

July 7th 2021

In comparison to DPP4i, SGLT2i may improve survival for patients with cirrhosis who require additional pharmacotherapy for DM beyond metformin, but confirmatory studies are necessary (Diabetes, Obesity and Metabolism)

Categories: Hepatology, News
Tags: Cirrhosis, DPP4 inhibitors, SGLT2 inhibitors

Categories: Hepatology
Tags: Cirrhosis, DPP4 inhibitors, SGLT2 inhibitors

The Effects of Glucagon-Like Peptide-1 Receptor Agonists and Dipeptydilpeptidase-4 Inhibitors on Blood Pressure and Cardiovascular Complications in Diabetes

June 30th 2021

The cumulative evidence from the recent cardiovascular outcome trials suggests that the effects of GLP-1R activation have a beneficial effect on blood pressure and cardiovascular diseases. However, a robust meta-analysis is needed to compare the controversial results of the different papers in the current literature (Journal of Diabetes Research)

Categories: Cardiovascular, Hypertension, Medication, News
Tags: DPP4 inhibitors, GLP1

Categories: Cardiovascular, Hypertension, Medication
Tags: DPP4 inhibitors, GLP1

Glucose-lowering Drugs and Hospitalization for Heart Failure: A Systematic Review and Additive-effects Network Meta-Analysis with over 500,000 Patient-Years

June 17th 2021

The risk of HHF is reduced by SGLT2i as monotherapy or in combination with DPP4i and increased by TZD as monotherapy or in combination. Glucose-lowering provides an additive effect of reducing HHF (Journal of Clinical Endocrinology & Metabolism)

Categories: Cardiovascular, Medication, News
Tags: DPP4 inhibitors, SGLT2 inhibitors

Categories: Cardiovascular, Medication
Tags: DPP4 inhibitors, SGLT2 inhibitors

Lower Risk of Hospitalisation for Heart Failure, Kidney Disease and Death with Sodium Glucose Co‐Transporter‐2 Compared to Dipeptidyl Peptidase‐4 Inhibitors in Type 2 Diabetes Regardless of Prior Cardiovascular or Kidney Disease

May 12th 2021

SGLT2i were associated with reduced risk of all–cause mortality and hospitalisation for HF and CKD compared with DPP4–i, highlighting the need to introduce SGLT2i early in the management of T2D patients (Diabetes, Obesity and Metabolism)

Categories: Cardiovascular, Nephropathy, News
Tags: DPP4 inhibitors, SGLT2 inhibitors, Type 2 Diabetes

Categories: Cardiovascular, Nephropathy
Tags: DPP4 inhibitors, SGLT2 inhibitors, Type 2 Diabetes

Cardiovascular surrogate markers and cardiometabolic therapeutics: a viewpoint learned from clinical trials on dipeptidyl peptidase-4 inhibitors

February 12th 2021

In this commentary we discuss how we should interpret the effects of cardiometabolic therapeutics on vascular surrogate markers, based on viewpoints learned from the results of clinical trials on dipeptidyl peptidase-4 inhibitors (Cardiovascular Diabetology)

Categories: Cardiovascular, News
Tags: DPP4 inhibitors

Categories: Cardiovascular
Tags: DPP4 inhibitors

Use of Dipeptidyl Peptidase‐4 inhibitors and prognosis of COVID‐19 in hospitalized patients with type 2 diabetes: a propensity score analysis from the CORONADO study

February 3rd 2021

These data support the safety of DPP‐4 inhibitors for diabetes management during the COVID‐19 pandemic and they should not be discontinued (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: COVID ‐19, DPP4 inhibitors, Type 2 Diabetes

Categories: Medication
Tags: COVID ‐19, DPP4 inhibitors, Type 2 Diabetes

Impact of Comorbidities and Glycemia at Admission and Dipeptidyl Peptidase 4 Inhibitors in Patients With Type 2 Diabetes With COVID-19

October 7th 2020

Plasma glucose levels at admission and antidiabetes drugs may influence the survival of COVID-19 patients affected by type 2 diabetes (Diabetes Care)

Categories: News, Pathology
Tags: DPP4 inhibitors, Type 2 Diabetes

Categories: Pathology
Tags: DPP4 inhibitors, Type 2 Diabetes

Role of incretin‐based therapy in hospitalized patients with type 2 diabetes

September 18th 2019

Based on the available evidence, dipeptidyl peptidase‐4 inhibitors should be considered for hospitalized patients with type 2 diabetes and an algorithm for this is proposed (Figure 1). In relation to the use of GLP‐1 and GLP‐1 receptor agonist, further research is required to help define their role in the inpatient setting (Journal of Diabetes Investigation)

Categories: Medication, News
Tags: DPP4 inhibitors, Type 2 Diabetes

Categories: Medication
Tags: DPP4 inhibitors, Type 2 Diabetes

Cardiovascular outcome trials of glucose-lowering medications: an update

January 3rd 2019

In summary, taking into account the findings from these new studies, it is suggested that a GLP-1RA should be offered to all people with CVD and type 2 diabetes, and SGLT2 inhibitors should be prescribed for those at high risk of heart failure or with progressive decline in eGFR. DPP4 inhibitors are a safe choice within the glucose-lowering stepped algorithm (Diabetologia)

Categories: Cardiovascular, News
Tags: DPP4 inhibitors, GLP-1RA, SGLT2 inhibitors

Categories: Cardiovascular
Tags: DPP4 inhibitors, GLP-1RA, SGLT2 inhibitors

Dipeptidyl peptidase‐4 inhibitor use is associated with decreased risk of fracture in patients with type 2 diabetes: a population‐based cohort study

August 14th 2018

The results of this study supported the premise that DPP‐4i usage is associated with a reduced risk of all‐cause fractures and upper extremity fractures in patients with type 2 diabetes (British Journal of Clinical Pharmacology)

Categories: Medication, News
Tags: DPP4 inhibitors, fracture, Type 2 Diabetes

Categories: Medication
Tags: DPP4 inhibitors, fracture, Type 2 Diabetes

Different Glucagon Effects During DPP-4 Inhibition versus SGLT-2 Inhibition in Metformin-Treated Type 2 Diabetes Subjects

March 8th 2018

We conclude that treatment with DPP-4 inhibition with vildagliptin results in 15% lower fasting and postprandial glucagon levels compared to SGLT-2 inhibition with dapagliflozin. DPP-4 inhibition also induces a more rapid insulin secretion and higher levels of intact incretin hormones resulting in stronger feedback inhibition of incretin hormone secretion than SGLT-2 inhibition (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: DPP4 inhibitors, metformin, SGLT2 inhibitors, Type 2 Diabetes

Categories: Medication
Tags: DPP4 inhibitors, metformin, SGLT2 inhibitors, Type 2 Diabetes

Second line initiation of insulin compared with DPP-4 inhibitors after metformin monotherapy is associated with increased risk of all-cause mortality, cardiovascular events, and severe hypoglycemia

December 20th 2016

Initiation of insulin, compared with DPP-4i treatment, was associated with an increased risk of subsequent all-cause mortality, fatal and nonfatal CVD, and severe hypoglycemia. Results from randomized trials will be important to elucidate causal relationships (Diabetes Research and Clinical Practice)

Categories: Medication, News
Tags: DPP4 inhibitors, insulin

Categories: Medication
Tags: DPP4 inhibitors, insulin

The Safety of Dipeptidyl Peptidase 4 Inhibitors and the Risk for Heart Failure

April 14th 2016

Owing to the well-documented microvascular benefit of improved glycemic control, the identification of cardiovascular-safe diabetes drugs that effectively lower glucose remains an important clinical need. The incretin therapies thus fulfill this goal. Ultimately, we need diabetes drugs that also reduce cardiovascular risk, and that will only be demonstrated through a continued commitment to long-term outcome studies (JAMA Cardiology)

Categories: Medication, News
Tags: DPP4 inhibitors, incretin

Categories: Medication
Tags: DPP4 inhibitors, incretin

Effects on Clinical Outcomes of Adding Dipeptidyl Peptidase-4 Inhibitors Versus Sulfonylureas to Metformin Therapy in Patients With Type 2 Diabetes Mellitus

October 13th 2015

Compared with sulfonylureas, DPP-4 inhibitors were associated with lower risks for all-cause death, MACEs, ischemic stroke, and hypoglycemia when used as add-ons to metformin therapy (Annals of Internal Medicine)

Categories: Medication, News
Tags: DPP4 inhibitors, metformin, sulfonylureas, Type 2 Diabetes

Categories: Medication
Tags: DPP4 inhibitors, metformin, sulfonylureas, Type 2 Diabetes

Safety and effectiveness of dipeptidyl peptidase-4 inhibitors versus intermediate-acting insulin or placebo for patients with type 2 diabetes failing two oral antihyperglycaemic agents

January 22nd 2015

DPP-4 inhibitors were superior to placebo in reducing HbA1c levels in adults with T2DM taking at least two oral agents. Compared with placebo, no safety signals were detected with DPP-4 inhibitors and there was a reduced risk of infection. There was no significant difference in HbA1c observed between NPH and placebo or NPH and DPP-4 inhibitors (BMJ Open)

Categories: Medication, News
Tags: DPP4 inhibitors, HbA1c, Type 2 Diabetes

Categories: Medication
Tags: DPP4 inhibitors, HbA1c, Type 2 Diabetes

Subscribe

subscribe-iconFREE weekly updates by email Please CLICK HERE

Gold Sponsors

Novo NordiskAstraZenecaBoehringer IngelheimNapp Diabetes

Silver Sponsors

About Ascensia Diabetes CareWelsh Endocrinology and Diabetes Society (WEDS)Abbott Diabetes Care

FUNDING NOTICE

The Glycosmedia website and newsletter has been made possible with funding support from our sponsors. None of our sponsors have control over the content of the website, newsletter, apps, Twitter feed or RSS newsfeed.

For information about sponsorship and advertising please contact our editor-in-chief Jim Young jim@glycosmedia.com

Advertisers

CRC Press

The organisations advertising in this section do not have any input into, or editorial control over the content of this website.

Categories

  • Audits
  • Bariatric
  • Biochemistry
  • Cardiovascular
  • Devices
  • Diagnosis
  • Diet
  • Education
  • Epidemiology
  • Genetics
  • Gestational
  • Guidance
  • Guidelines
  • Hepatology
  • Hypertension
  • Immunology
  • Management
  • Media
  • Medication
  • Meetings
  • Monitoring
  • Nephrology
  • Neuropathy
  • Nephropathy
  • Obesity
  • Ophthalmology
  • Paediatrics
  • Pathology
  • Pharma
  • Pharmacology
  • Physiology
  • Podiatry
  • Prediabetes
  • Prevalence
  • Prevention
  • Psychological
  • Reports
  • Research
  • Screening
  • Sponsorship
  • Technology
  • Testing
  • Transplantation
  • Treatment
  • Wound Care

To see all articles associated with a category just click on the category name.

Popular Tags

ADA BMI canagliflozin CGM CKD closed-loop COVID-19 dapagliflozin DPP4 DPP4 inhibitors elderly Empagliflozin exenatide GLP-1 RA GLP-1RA GLP1 glycaemic control HbA1c heart failure hyperglycemia hypoglycemia incretin insulin insulin pump Insulin resistance Ketoacidosis liraglutide metformin microvascular mortality NICE pioglitazone retinopathy semaglutide SGLT2 inhibitors sitagliptin statin sulfonylureas Type 1 Diabetes Type 2 Diabetes

To see all articles associated with a tag just click on the tag name.

Complete list of Tags ››

Join us on Facebook

Join us on Facebook

Please share Glycosmedia:

Follow us on Twitter

My Tweets

mobileGlycosmedia is also available as an App:

For iPhone and iPad | For Android devices


Sponsorship and Advertising

For information about sponsorship and advertising please contact our editor-in-chief Jim Young jim@glycosmedia.com

Copyright © 2022 Glycosmedia Partnership