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Diabetes News

Tag: hyperglycemia


Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry

May 16th 2022

Type 2 diabetic AMI patients receiving SGLT2-I exhibited significantly reduced inflammatory response and smaller infarct size compared to those receiving other OAD agents independently of glucose-metabolic control (Cardiovascular Diabetology)

Categories: Cardiovascular, Medication, News
Tags: AMI, hyperglycemia, SGLT2 inhibitors

Categories: Cardiovascular, Medication
Tags: AMI, hyperglycemia, SGLT2 inhibitors

Impact of Diabetes Mellitus on the Immunity of Tuberculosis Patients: A Retrospective, Cross-Sectional Study

April 7th 2022

Hyperglycemia is a risk factor for pulmonary cavity formation and lobe lesions in patients with TB-DM and suppresses the absolute counts of total T lymphocytes, CD8+ T lymphocytes, and NK cells in patients with TB-DM. The potential mechanism may involve the downregulation of innate and adaptive immune responses (Risk Management and Healthcare Policy)

Categories: News, Pathology
Tags: hyperglycemia, tuberculosis

Categories: Pathology
Tags: hyperglycemia, tuberculosis

Plasma 1,5-anhydro-D-glucitol is associated with peripheral nerve function and diabetic peripheral neuropathy in patients with type 2 diabetes and mild-to-moderate hyperglycemia

January 30th 2022

Low plasma 1,5-AG is closely associated with impaired peripheral nerve function and DPN in T2D patients under mild-to-moderate hyperglycemia (Diabetology & Metabolic Syndrome)

Categories: Neuropathy, News
Tags: hyperglycemia, Type 2 Diabetes

Categories: Neuropathy
Tags: hyperglycemia, Type 2 Diabetes

Continuous Glucose Monitoring in Adults With Type 1 Diabetes With 35 Years Duration From the DCCT/EDIC Study

January 26th 2022

The small subset of participants using routine CGM and insulin pumps had fewer hypoglycemic and hyperglycemic excursions and lower HbA1c levels. Thus, strategies to lower meal-stimulated hyperglycemia during the day and prevent hypoglycemia at night are relevant clinical goals in older patients with type 1 diabetes (Diabetes Care)

Categories: Monitoring, News
Tags: CGM, hyperglycemia, hypoglycemia, insulin pump, Type 1 Diabetes

Categories: Monitoring
Tags: CGM, hyperglycemia, hypoglycemia, insulin pump, Type 1 Diabetes

National Diabetes Audit, Non-Diabetic Hyperglycaemia, 2020-21, Diabetes Prevention Programme, Data Release

November 11th 2021

This short report uses data collected from GP practices alongside the National Diabetes Audit (NDA) for the period January 2020 to March 2021 inclusive. This report is for England only (NHS Digital)

Categories: Audits, News
Tags: hyperglycemia

Categories: Audits
Tags: hyperglycemia

Reappearance of C-Peptide During the Third Trimester of Pregnancy in Type 1 Diabetes: Pancreatic Regeneration or Fetal Hyperinsulinism?

August 12th 2021

First maternal C-peptide appearance at 34 weeks was associated with midtrimester hyperglycemia, elevated cord blood C-peptide, and high rates of neonatal complications. This suggests transfer of C-peptide from fetal to maternal serum and is inconsistent with pregnancy-related β-cell regeneration (Diabetes Care)

Categories: Gestational, News
Tags: C-peptide, hyperglycemia, Type 1 Diabetes

Categories: Gestational
Tags: C-peptide, hyperglycemia, Type 1 Diabetes

Management of diabetes and hyperglycaemia in the hospital

January 28th 2021

In this Review, we summarise the evidence from observational studies and clinical trials focusing on inpatient care of people with diabetes and stress hyperglycaemia, including the use of insulin and non-insulin treatment strategies, treatment goals, and the application of new technologies in the hospital setting (Lancet Diabetes & Endocrinology)

Categories: Management, News
Tags: hyperglycemia

Categories: Management
Tags: hyperglycemia

Caring for Hospitalized Patients with Diabetes Mellitus, Hyperglycemia, and COVID-19: Bridging the Remaining Knowledge Gaps

November 27th 2020

Changes in diabetes-related protocols and new technology can be deployed in the inpatient setting to potentially improve healthcare worker and patient safety; however, one must weigh the risks and benefits of implementation during a pandemic (Current Diabetes Reports)

Categories: News, Treatment
Tags: COVID-19, hyperglycemia

Categories: Treatment
Tags: COVID-19, hyperglycemia

National Diabetes Audit, Non-Diabetic Hyperglycaemia, 2019- 2020, Diabetes Prevention Programme, Data Release

November 20th 2020

This short report uses data collected from GP practices alongside the National Diabetes Audit (NDA) for the period January 2019 to March 2020 inclusiv (NHS Digital)

Categories: Audits, News
Tags: hyperglycemia

Categories: Audits
Tags: hyperglycemia

Multicentre analysis of hyperglycaemic hyperosmolar state and diabetic ketoacidosis in type 1 and type 2 diabetes

June 3rd 2020

HHS/DKA occurred mostly in T1D and younger patients. However, both also occurred in T2D, which is of great importance in the treatment of diabetes. Better education programmes are necessary to prevent decompensation and comorbidities (Acta Diabetologica)

Categories: News, Pathology
Tags: hyperglycemia, hyperosmolar state, Type 1 Diabetes, Type 2 Diabetes

Categories: Pathology
Tags: hyperglycemia, hyperosmolar state, Type 1 Diabetes, Type 2 Diabetes

Oral antidiabetes agents for the management of inpatient hyperglycaemia: so far, yet so close

May 24th 2020

The administration of dipeptidyl peptidase‐4 inhibitors to specific groups of inpatients might be a safe and effective alternative to insulin (Diabetic Medicine)

Categories: Medication, News
Tags: hyperglycemia, oral

Categories: Medication
Tags: hyperglycemia, oral

Hyperglycemia in Medically Critically Ill Patients: Risk Factors and Clinical Outcomes

April 14th 2020

In our high acuity medically critically ill patient population, achieving time-weighted average daily blood glucose levels <180mg/dl reliably while in the ICU significantly decreased the odds of subsequent hospital mortality. Suboptimal glycemic control during the ICU stay, on the other hand, significantly increased the odds of a longer-than-predicted ICU and hospital stay (American Journal of Medicine)

Categories: News, Treatment
Tags: hyperglycemia, ICU

Categories: Treatment
Tags: hyperglycemia, ICU

The impact of hyperglycemia on urinary albumin excretion in recent onset diabetes mellitus type II

April 9th 2020

Hyperglycemic state emerges as a powerful predictor of increased UAE even at the earliest stages of diabetes. The relative contribution of hypertension and macrovascular dysfunction to the development of microalbuminuria seems to be obscured by hyperglycemia, even in patients whose diabetes onset does not exceed a few months’ time(BMC Nephrology)

Categories: Monitoring, News
Tags: hyperglycemia, microalbuminuria, Type 2 Diabetes, UAE

Categories: Monitoring
Tags: hyperglycemia, microalbuminuria, Type 2 Diabetes, UAE

Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patients

June 2nd 2019

This review covers recommendations for acute management of diabetic ketoacidosis and HHS, the complications associated with these disorders, and methods for preventing recurrence. It also discusses why many patients who present with these disorders are at high risk for hospital readmissions, early morbidity, and mortality well beyond the acute presentation (BMJ)

Categories: Management, News
Tags: hyperglycemia, hyperosmolar, Ketoacidosis

Categories: Management
Tags: hyperglycemia, hyperosmolar, Ketoacidosis

Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patients

May 29th 2019

This review covers recommendations for acute management of diabetic ketoacidosis and HHS, the complications associated with these disorders, and methods for preventing recurrence. It also discusses why many patients who present with these disorders are at high risk for hospital readmissions, early morbidity, and mortality well beyond the acute presentation (BMJ)

Categories: News, Pathology
Tags: Diabetic Ketoacidosis, hyperglycemia

Categories: Pathology
Tags: Diabetic Ketoacidosis, hyperglycemia

Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism

February 21st 2019

Offspring exposed to untreated GDM in utero are insulin resistant with limited β-cell compensation compared with offspring of mothers without GDM. GDM is significantly and independently associated with childhood IGT  (Diabetes Care)

Categories: Gestational, News
Tags: hyperglycemia

Categories: Gestational
Tags: hyperglycemia

Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Glycemia and Childhood Glucose Metabolism

February 21st 2019

Across the maternal glucose spectrum, exposure to higher levels in utero is significantly associated with childhood glucose and insulin resistance independent of maternal and childhood BMI and family history of diabetes (Diabetes Care)

Categories: Gestational, News
Tags: hyperglycemia

Categories: Gestational
Tags: hyperglycemia

A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes

June 26th 2018

The Pankowska Equation resulted in reduced postprandial hyperglycaemia at the expense of an increase in hypoglycaemia. There were no significant differences when carbohydrate counting was compared to the Food Insulin Index. Further research is required to optimize prandial insulin dosing (Diabetic Medicine)

Categories: News, Paediatrics
Tags: hyperglycemia, hypoglycemia, insulin, prandial, Type 1 Diabetes

Categories: Paediatrics
Tags: hyperglycemia, hypoglycemia, insulin, prandial, Type 1 Diabetes

Glucose alert system improves health professional responses to adverse glycaemia and reduces the number of hyperglycaemic episodes in non‐critical care inpatients

April 11th 2018

Use of a novel glucose alert system improved health professional responses to adverse glycaemia and decreased hyperglycaemia in the hospital setting (Diabetic Medicine)

Categories: Monitoring, News
Tags: hyperglycemia, inpatient

Categories: Monitoring
Tags: hyperglycemia, inpatient

The Pathophysiology of Hyperglycemia in Older Adults: Clinical Considerations

March 21st 2017

This paper reviews the pathophysiology of type 2 diabetes among older adults and the implications for hyperglycemia management in this population (Diabetes Care)

Categories: News, Pathology
Tags: hyperglycemia, Type 2 Diabetes

Categories: Pathology
Tags: hyperglycemia, Type 2 Diabetes
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