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Diabetes News

Tag: hypoglycemia


The Association Between HbA1c and Time in Hypoglycemia During CGM and Self-Monitoring of Blood Glucose in People With Type 1 Diabetes and Multiple Daily Insulin Injections

July 9th 2020

CGM is associated with considerably less time in hypoglycemia than SMBG at a broad range of HbA1c levels and is crucial for patients with MDI treatment if they are to have a chance to approach hypoglycemia targets (Diabetes Care)

Categories: Monitoring, News
Tags: CGM, hypoglycemia, Type 1 Diabetes

Categories: Monitoring
Tags: CGM, hypoglycemia, Type 1 Diabetes

Episodes of severe hypoglycemia is associated with a progressive increase in hemoglobin A1c in children and adolescents with type 1 diabetes

April 19th 2020

Severe hypoglycemia was followed by a progressive and lasting increase in HbA1c among Danish children and adolescents with T1D. Thus, in addition to the known risk of new episodes of hypoglycemia and cognitive impairment, SH contributes to long‐term diabetes complications (Pediatric Diabetes)

Categories: News, Pathology
Tags: HbA1c, hypoglycemia, Type 1 Diabetes

Categories: Pathology
Tags: HbA1c, hypoglycemia, Type 1 Diabetes

Association between reduced kidney function and incident hypoglycemia in people with diabetes; the Stockholm CREAtinine Measurements (SCREAM) project

April 9th 2020

In this large, observational study, low eGFR strongly associated with the occurrence, severity and fatality of hypoglycemia in persons with diabetes (Diabetes, Obesity and Metabolism)

Categories: Nephropathy, News
Tags: hypoglycemia

Categories: Nephropathy
Tags: hypoglycemia

Risk of severe hypoglycaemia and its impact in type 2 diabetes in DEVOTE

April 7th 2020

The risk score demonstrated that a high risk of severe hypoglycaemia was associated with a high incidence of MACE and all‐cause mortality and that, in this high‐risk group, those treated with degludec had a lower incidence of MACE. These observations support the hypothesis that hypoglycaemia is a risk factor for cardiovascular events (Diabetes, Obesity and Metabolism)

Categories: Monitoring, News
Tags: hypoglycemia, Type 2 Diabetes

Categories: Monitoring
Tags: hypoglycemia, Type 2 Diabetes

Hypoglycemia during Short-Term Intensive Insulin Therapy and Its Association with Long-Term Glycemic Remission in Patients with Newly Diagnosed Type 2 Diabetes

February 19th 2020

Mild hypoglycemic episodes during the continuing insulin dose reduction period indicate a long-term drug-free euglycemic remission in patients with newly diagnosed type 2 diabetes. However, the insulin dosage should be reduced even more quickly in the future treatment to decrease the potential harms (Journal of Diabetes Research)

Categories: News, Treatment
Tags: hypoglycemia, insulin, remission, Type 2 Diabetes

Categories: Treatment
Tags: hypoglycemia, insulin, remission, Type 2 Diabetes

How Valid Are the New Hypoglycemia Definitions for Use in Clinical Trials?

January 21st 2020

The deeper analysis of data from the well-powered SWITCH studies does support that the new IHSG level 2 definition compared with the previous ADA definition can result in statistically more robust findings when comparing insulins (Diabetes Care)

Categories: News, Research
Tags: hypoglycemia, SWITCH

Categories: Research
Tags: hypoglycemia, SWITCH

Hypoglycemic Confidence in the Partners of Adults with Type 1 Diabetes

November 8th 2019

HC is an important facet of the experiences of T1D partners. It is related to, yet distinct from, hypoglycemic fear. The Partner-HCS is a reliable, valid method for assessing HC in partners of T1D adults (Diabetes Technology and Therapeutics)

Categories: Management, News
Tags: hypoglycemia, Type 1 Diabetes

Categories: Management
Tags: hypoglycemia, Type 1 Diabetes

Severe Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes

August 20th 2019

Intensive glucose-lowering therapy, particularly among vulnerable clinically complex adults, is strongly discouraged because it may lead to hypoglycemia. However, intensive treatment was equally prevalent among US adults, irrespective of clinical complexity (Mayo)

Categories: Management, News
Tags: hypoglycemia

Categories: Management
Tags: hypoglycemia

Efficacy of two telemonitoring systems to improve glycaemic control during basal insulin initiation in patients with type 2 diabetes: The TeleDiab‐2 randomized controlled trial

July 4th 2019

Both telemonitoring systems improved glycaemic control to a similar extent, without increasing hypoglycaemic episodes (Diabetes, Obesity and Metabolism)

Categories: Monitoring, News
Tags: hypoglycemia, telemonitoring, Type 2 Diabetes

Categories: Monitoring
Tags: hypoglycemia, telemonitoring, Type 2 Diabetes

Use of sensor‐integrated pump therapy to reduce hypoglycaemia in people with Type 1 diabetes: a real‐world study in the UK

May 28th 2019

Real‐world UK data show that increasing automation of insulin suspension reduces hypoglycaemia exposure in people with Type 1 diabetes (Diabetic Medicine)

Categories: News, Treatment
Tags: hypoglycemia, insulin, insulin pump, Type 1 Diabetes

Categories: Treatment
Tags: hypoglycemia, insulin, insulin pump, Type 1 Diabetes

First aid glucose administration routes for symptomatic hypoglycaemia

May 15th 2019

These results have important implications for individuals with symptoms of mild to moderate hypoglycaemia, their family members and first‐aid providers (Cochrane)

Categories: News, Treatment
Tags: hypoglycemia

Categories: Treatment
Tags: hypoglycemia

Impaired awareness of hypoglycemia: a new risk factor for adverse pregnancy outcomes in type 1 diabetes

May 8th 2019

Impaired awareness of hypoglycemia: a new risk factor for adverse pregnancy outcomes in type 1 diabetes (Diabetes Research and Clinical Practice)

Categories: Gestational, News
Tags: hypoglycemia, Type 1 Diabetes

Categories: Gestational
Tags: hypoglycemia, Type 1 Diabetes

Low versus high carbohydrate diet in type 1 diabetes: A 12‐week randomized open‐label crossover study

April 24th 2019

Compared with an intake of 250 g of carbohydrate per day, restriction of carbohydrate intake to 100 g per day in adults with type 1 diabetes reduced time spent in hypoglycaemia, glycaemic variability and weight with no effect on cardiovascular risk factors (Diabetes, Obesity and Metabolism)

Categories: Diet, News
Tags: hypoglycemia, Type 1 Diabetes

Categories: Diet
Tags: hypoglycemia, Type 1 Diabetes

Double‐blind, randomized clinical trial comparing the efficacy and safety of continuing or discontinuing the dipeptidyl peptidase‐4 inhibitor sitagliptin when initiating insulin glargine therapy in patients with type 2 diabetes

April 1st 2019

When initiating insulin glargine therapy, continuation of sitagliptin, compared with discontinuation, resulted in a clinically meaningful greater reduction in HbA1c without an increase in hypoglycaemia (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: HbA1c, hypoglycemia, insulin, sitagliptin, Type 2 Diabetes

Categories: Medication
Tags: HbA1c, hypoglycemia, insulin, sitagliptin, Type 2 Diabetes

Glycemic goal attainment and hypoglycemia outcomes in type 2 diabetes patients initiating insulin glargine 300 units/mL or 100 units/mL: Real‐world results from the DELIVER Naïve cohort study

March 7th 2019

Among insulin‐naïve adults with T2D, Gla‐300 was associated with significantly better HbA1c reductions (latest value during 90–180‐day follow‐up) and similar or improved hypoglycemia outcomes (3‐ and 6‐month follow‐up) than Gla‐100 (Diabetes, Obesity and Metabolism)

Categories: News, Treatment
Tags: hypoglycemia, Type 2 Diabetes

Categories: Treatment
Tags: hypoglycemia, Type 2 Diabetes

Sliding scale insulin for non‐critically ill hospitalised adults with diabetes mellitus

December 6th 2018

Based on low‐ to very low‐certainty evidence, our results for non‐critically ill hospitalised adults with diabetes mellitus in the medical and surgical in‐hospital setting showed that a basal‐bolus insulin strategy that applied higher total daily doses of insulin than the sliding scale insulin regimen might result in better short‐term glycaemic control but might also cause an increase in severe hypoglycaemic episodes (Cochrane Systematic Review)

Categories: News, Treatment
Tags: hospital, hypoglycemia, insulin, sliding scale

Categories: Treatment
Tags: hospital, hypoglycemia, insulin, sliding scale

Asymptomatic hypoglycaemia in Type 1 diabetes: incidence and risk factors

October 28th 2018

Asymptomatic hypoglycaemia constitutes the majority of hypoglycaemic events in Type 1 diabetes. Reduced hypoglycaemia awareness and high insulin dose are risk factors for asymptomatic hypoglycaemia, but other conventional risk factors for severe hypoglycaemia do not correlate with risk of asymptomatic episodes (Diabetic Medicine)

Categories: News, Pathology
Tags: hypoglycemia, insulin, Type 1 Diabetes

Categories: Pathology
Tags: hypoglycemia, insulin, Type 1 Diabetes

Development and validation of a risk prediction model for severe hypoglycemia in adult patients with type 2 diabetes

October 26th 2018

This 14-variable prediction model for SH events may be a useful tool to identify high-risk patients and guide prevention of SH in adult patients with T2DM  (Clinical Epidemiology)

Categories: Monitoring, News
Tags: hypoglycemia, Type 2 Diabetes

Categories: Monitoring
Tags: hypoglycemia, Type 2 Diabetes

Inpatient hypoglycaemia; should we should we focus on the guidelines, the targets or our tools?

September 6th 2018

These guidelines suggest using lower limits of glucose targets varying from 4.0 to 6.0 mmol/l [2–4]. Levy et al. propose a lower glucose limit of 5 mmol/l with the catchphrase ‘stop at 5 and keep the inpatient alive’ (Diabetic Medicine)

Categories: Management, News
Tags: hypoglycemia, inpatient

Categories: Management
Tags: hypoglycemia, inpatient

Development of a model to predict 5-year risk of severe hypoglycemia in patients with type 2 diabetes

August 13th 2018

Using the ACCORD data, we identified attributes to predict 5-year risk of SH in patients with T2DM, which warrant evaluation in broader populations to determine applicability (BMJ Open, Diabetes Research & Care)

Categories: News, Screening
Tags: hypoglycemia, Type 2 Diabetes

Categories: Screening
Tags: hypoglycemia, Type 2 Diabetes
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