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Diabetes News

Tag: insulin sensitivity


Diet-induced fasting ghrelin elevation reflects the recovery of insulin sensitivity and visceral adiposity regression

October 17th 2021

Diet-induced FGL elevation may reflect insulin sensitivity recovery and VAT regression beyond weight-loss, specifically among men. Green-MED diet is associated with greater FGL elevation (Journal of Clinical Endocrinology & Metabolism)

Categories: Diet, News
Tags: ghrelin, insulin sensitivity

Categories: Diet
Tags: ghrelin, insulin sensitivity

Estimated insulin sensitivity, cardiovascular risk and hepatic steatosis after 12 years from the onset of T1D

June 3rd 2021

Adiposity, glucose and lipid control over the follow-up are likely to influence both. Enhanced adiposity seems paramount for the onset of hepatic steatosis in T1D patients alike in healthy youths (Diabetes/Metabolism Research and Reviews)

Categories: Cardiovascular, News, Pathology
Tags: hepatic steatosis, insulin sensitivity, Type 1 Diabetes

Categories: Cardiovascular, Pathology
Tags: hepatic steatosis, insulin sensitivity, Type 1 Diabetes

Longitudinal changes in glucose metabolism in women with gestational diabetes, from late pregnancy to the postpartum period

December 9th 2019

In women with GDM, delivery was associated with improvement in both insulin sensitivity and insulin production within the first few days. Improvement in insulin production persisted for 6–12 weeks, but insulin sensitivity deteriorated slightly (Diabtologia)

Categories: Gestational, News
Tags: insulin sensitivity

Categories: Gestational
Tags: insulin sensitivity

Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis

July 20th 2016

This meta-analysis of randomised controlled feeding trials provides evidence that dietary macronutrients have diverse effects on glucose-insulin homeostasis. In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen with PUFA, which was linked to improved glycaemia, insulin resistance, and insulin secretion capacity (PLOS Medicine)

Categories: Diet, News
Tags: homeostasis, Insulin resistance, insulin sensitivity

Categories: Diet
Tags: homeostasis, Insulin resistance, insulin sensitivity

Relationship between insulin sensitivity and insulin secretion rate: not necessarily hyperbolic

December 16th 2015

These findings demonstrate that the physiological relationship between insulin sensitivity and insulin secretion rate is not necessarily hyperbolic, but will vary with the method(s) by which it is determined (Diabetic Medicine)

Categories: Monitoring, News
Tags: insulin secretion, insulin sensitivity

Categories: Monitoring
Tags: insulin secretion, insulin sensitivity

10-year trajectory of β-cell function and insulin sensitivity in the development of type 2 diabetes: a community-based prospective cohort study

November 12th 2015

Decreased β-cell function, which might be determined partly by genetic factors, and impaired β-cell compensation for progressive decline in insulin sensitivity are crucial factors in the deterioration of glucose tolerance (The Lancet Diabetes & Endocrinology)

Categories: News, Pathology
Tags: insulin sensitivity, Type 2 Diabetes, β-cell function

Categories: Pathology
Tags: insulin sensitivity, Type 2 Diabetes, β-cell function

Changes in insulin sensitivity and secretion after sleeve gastrectomy

November 10th 2015

Sleeve gastrectomy improved insulin sensitivity and reduced insulin secretion within 6 months after surgery. Although there was a correlation between insulin sensitivity and bodyweight, the major driver of the improvement in insulin sensitivity was GLP-1 secretion (British Journal of Surgery)

Categories: News, Obesity
Tags: insulin sensitivity, sleeve gastrectomy

Categories: Obesity
Tags: insulin sensitivity, sleeve gastrectomy

Bolus Estimation—Rethinking the Effect of Meal Fat Content

September 5th 2015

In addition to considering the putative delay in gastric emptying associated with HF meals, we suggest that clinicians reviewing patient records consider that the fat content of these meals may alter SI (Diabetes Technology and Therapeutics)

Categories: Diet, News
Tags: bolus, fat, insulin sensitivity

Categories: Diet
Tags: bolus, fat, insulin sensitivity

Triglyceride glucose index as a surrogate measure of insulin sensitivity in obese adolescents with normoglycemia, prediabetes, and type 2 diabetes mellitus: comparison with the hyperinsulinemic–euglycemic clamp

August 18th 2015

The TyG index affords an easily and widely available simple laboratory method as a surrogate estimate of insulin sensitivity that could be used repeatedly in large-scale observational and/or interventional cohorts of OB (Pediatric Diabetes)

Categories: Monitoring, News
Tags: insulin sensitivity, Triglyceride glucose index

Categories: Monitoring
Tags: insulin sensitivity, Triglyceride glucose index

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