In individuals with normal glucose tolerance, β-cell function and insulin sensitivity gradually decrease with a deterioration in the lipid profile. Not only fasting TG but also postprandial TG concentrations are independent risk factors for impaired β-cell function and insulin resistance (Journal of Diabetes Investigation)
Diabetes News
Tag: lipids
Effect of blood lipid variability on mortality in patients with type 2 diabetes: a large single-center cohort study
Blood lipid variability except for triglyceride variability was associated with all-cause and cardiovascular mortality in patients with type 2 diabetes (Cardiovascular Diabetology)
Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort
A lifestyle-related lipidomic profile strongly predicts T2DM development beyond current risk factors. Further studies are warranted to test if lifestyle interventions modifying this lipidomic profile can prevent T2DM (Diabetes Care)
Maternal Non-glycemic Contributors to Fetal Growth in Obesity and Gestational Diabetes: Spotlight on Lipids
Early vs. later gestational exposure to excess maternal fuels in fasting and postprandial conditions may differentially impact fetoplacental outcomes. Compelling evidence suggests that targeting interventions early in pregnancy beyond glucose may be critical to improve fetal growth patterns (Current Diabetes Reports)
Common medications used by patients with type 2 diabetes mellitus: what are their effects on the lipid profile?
This review focuses on known changes in the routine lipid profile (LDL-C, TGs, and HDL-C) observed with commonly prescribed medications for patients with T2DM, including antihyperglycemic agents, antihypertensive agents, weight loss medications, antibiotics, analgesics, oral contraceptives, and hormone replacement therapies (Cardiovascular Diabetology)
The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index
This study showed that women with GDM had significantly increased cholesterol levels, triacylglycerol levels, TG/HDL-C ratios, LDL-C/HDL-C ratios, and fasting glucose levels during early pregnancy. Moreover, early pregnancy cholesterol levels, triacylglycerol levels, TG/HDL-C ratios, LDL-C/HDL-C ratios, and fasting glucose levels were associated with GDM risk (Journal of Diabetes Research)
Influence of dietary fat and carbohydrates proportions on plasma lipids, glucose control and low-grade inflammation in patients with type 2 diabetes—The TOSCA.IT Study
The data support the potential for reducing the intake of fat and added sugars, preferring complex, slowly absorbable, carbohydrates (European Journal of Nutrition)
Glycosmedia is also available as an App: