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Diabetes News

Tag: microbiota


Gut microbiota changes after metabolic surgery in adult diabetic patients with mild obesity: a randomised controlled trial

June 29th 2021

This was the first RCT studying composite clinical, analytic, and microbiome changes in T2DM patients with class 1 obesity after RYGB versus standard medical therapy. The remarkable phenotypic improvement after surgery occurred concomitantly with changes in the gut microbiome, but at a lower level (Diabetology & Metabolic Syndrome)

Categories: Bariatric, News, Obesity
Tags: microbiota

Categories: Bariatric, Obesity
Tags: microbiota

The relationship between gut microbiota, short-chain fatty acids and type 2 diabetes mellitus: the possible role of dietary fibre

May 10th 2021

increasing daily fibre intake in the context of a healthy dietary pattern might be a valid tool to improve microbiota composition and activity to prevent metabolic diseases (Acta Diabetologica)

Categories: Diet, News
Tags: fibre, microbiota, Type 2 Diabetes

Categories: Diet
Tags: fibre, microbiota, Type 2 Diabetes

The Gut Microbiome as a Target for the Treatment of Type 2 Diabetes

June 22nd 2018

The studies discussed in this review suggest that individuals who are obese are likely to have an imbalance in gut microbiota composition and a ‘gut signature’ varying with metabolic control (Current Diabetes Reports)

Categories: Diet
Tags: microbiota, Type 2 Diabetes

Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid–Producing Microbiota in the Gut

November 22nd 2016

Our results support the hypothesis that metformin shifts gut microbiota composition through the enrichment of mucin-degrading A. muciniphila as well as several SCFA-producing microbiota. Future studies are needed to determine if these shifts mediate metformin’s glycemic and anti-inflammatory properties (Diabetes Care)

Categories: Medication, News
Tags: metformin, microbiota

Categories: Medication
Tags: metformin, microbiota

Heritable components of the human fecal microbiome are associated with visceral fat

September 28th 2016

Our results provide novel insights into the role of the fecal microbiota in cardio-metabolic disease with clear potential for prevention and novel therapies (Genome Biology)

Categories: Genetics, News
Tags: microbiota

Categories: Genetics
Tags: microbiota

Association between intestinal permeability and fecal microbiota composition in Italian children with beta cell autoimmunity at risk for type 1 diabetes

February 24th 2016

The results of this study validated the hypothesis that increased intestinal permeability together with differences in microbiota composition are contemporaneously associated with the pre-pathological condition of T1D, in a sample of Italian children (Diabetes/Metabolism Research and Reviews)

Categories: News, Pathology
Tags: intestinal permeability, microbiota, Type 1 Diabetes

Categories: Pathology
Tags: intestinal permeability, microbiota, Type 1 Diabetes

Gut microbiota and diet in patients with different glucose tolerance

November 11th 2015

The representation of Blautia, Serratia was lower in preD than in T2D patients, and even lower in those with normal glucose tolerance (Endocrine Connections)

Categories: News, Pathology
Tags: glucose tolerance, microbiota

Categories: Pathology
Tags: glucose tolerance, microbiota

Genetic Factors Drive Roles of Gut Bacteria in Diabetes and Obesity

September 3rd 2015

Joslin study examines how bacterial and mammalian genomics interact to boost insulin resistance and other metabolic disorders

Categories: Genetics, News
Tags: bacterial, gut, microbiota

Categories: Genetics
Tags: bacterial, gut, microbiota

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

August 4th 2015

Our results suggest that the gut microbiota may play a direct role in the reduction of adiposity observed after bariatric surgery (Cell Metabolism)

Categories: Bariatric, News
Tags: microbiota

Categories: Bariatric
Tags: microbiota

Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose Tolerant Humans: A Proof of Concept

June 19th 2015

Enrichment of gut microbiota with L. reuteri increases insulin secretion, possibly due to augmented incretin release, but does not directly affect insulin sensitivity or body fat distribution. This suggests that oral ingestion of one specific strain may serve as a novel therapeutic approach to improve glucose-dependent insulin release (Diabetes Care)

Categories: News, Treatment
Tags: microbiota

Categories: Treatment
Tags: microbiota

Alterations in Intestinal Microbiota Correlate with Susceptibility to Type 1 Diabetes

June 18th 2015

These observations suggest that altered intestinal microbiota may be associated with disease susceptibility (Diabetes)

Categories: News, Pathology
Tags: microbiota, Type 1 Diabetes

Categories: Pathology
Tags: microbiota, Type 1 Diabetes

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