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Diabetes News

Tag: microRNAs


Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells

March 3rd 2021

Our results demonstrate that diabetes mellitus induces a marked dysregulation of miRNAs associated with stem cell survival, proliferation and differentiation, and that therapeutic overexpression of prosurvival miR-30c-5p reduced diabetes-induced cell death and loss of MMP in CPCs via the newly identified target for miR-30c-5p, VDAC1 (Diabetologia)

Categories: Cardiovascular, News
Tags: microRNAs, progenitor

Categories: Cardiovascular
Tags: microRNAs, progenitor

Epigenetic effects of metformin: from molecular mechanisms to clinical implications

February 19th 2018

There is evidence that these alterations influence the epigenome and gene expression, and may contribute to the antidiabetic properties of metformin and potentially protect against cancer, cardiovascular disease, cognitive decline and aging. The expression levels of numerous microRNAs are also reportedly influenced by metformin treatment and may confer antidiabetic and anticancer activities (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: gene expression, microRNAs

Categories: Medication
Tags: gene expression, microRNAs

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