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Diabetes News

Tag: OGTT


Clinical characteristics, gestational weight gain and pregnancy outcomes in women with a history of gestational diabetes mellitus

July 8th 2021

Women with prior GDM have glucose and lipid metabolism disorders in the 1st trimester. Limited reduction of GWG before oral glucose tolerance test (OGTT) was insufficient to offset the adverse effects of glucose and lipid metabolism disorders in women with previous GDM (Diabetology & Metabolic Syndrome)

Categories: Gestational, News
Tags: 1st trimester, GWG, OGTT

Categories: Gestational
Tags: 1st trimester, GWG, OGTT

A systematic review on costs and cost-effectiveness of screening and prevention of type 2 diabetes in women with prior gestational diabetes: exploring uncharted territory

December 7th 2018

An oral glucose tolerance test per three years leads to the lowest cost per case detected, and prevention is potentially cost-effective or cost-saving. More health economic evaluations are needed that compare all relevant alternatives, including ‘doing nothing’ (Diabetes Research and Clinical Practice)

Categories: Gestational, News
Tags: OGTT, Type 2 Diabetes

Categories: Gestational
Tags: OGTT, Type 2 Diabetes

The shape of the glucose concentration curve during an oral glucose tolerance test predicts risk for type 1 diabetes

December 14th 2017

Those with biphasic glucose curves have a lower risk of progression to type 1 diabetes than those with monophasic curves, and the risk among the monophasic group is increased when the glucose peak occurs at 90 min than at 30 min. Differences in glucose curve shapes between the monophasic and biphasic groups appear to be related to C-peptide responses (Diabetologia)

Categories: News, Screening
Tags: curve, OGTT, Type 1 Diabetes

Categories: Screening
Tags: curve, OGTT, Type 1 Diabetes

Screening for diabetes prevention with diabetes risk scores – A balancing act

November 16th 2017

A blood test post non-invasive risk assessment is a worthwhile step in the process of enrolling participants in a diabetes prevention program. Nevertheless, there will be ineligible individuals who proceed to diabetes (Diabetes Research and Clinical Practice)

Categories: News, Screening
Tags: OGTT

Categories: Screening
Tags: OGTT

One-hour post-load hyperglycemia combined with HbA1c identifies pre-diabetic individuals with a higher cardio-metabolic risk burden

September 1st 2016

Hyperglycemia at 1-hour during an OGTT may be a useful tool to identify a subset of individuals within HbA1c-defined glycemic categories at higher risk of developing type 2 diabetes and cardiovascular disease (Atherosclerosis)

Categories: News, Screening
Tags: HbA1c, OGTT

Categories: Screening
Tags: HbA1c, OGTT

Early diabetes screening in women with previous gestational diabetes: a new insight

August 27th 2016

OGTT performed early in postpartum is a useful tool for identifying women with previous GDM who must perform an OGTT 6 weeks after delivery (Diabetology & Metabolic Syndrome)

Categories: Gestational, News
Tags: OGTT

Categories: Gestational
Tags: OGTT

Delayed insulin secretion response during an OGTT is associated with an increased risk for incidence of diabetes in NGT subjects

August 17th 2016

NGT subjects with late insulin responses had defective early insulin secretion and were at higher risk of developing diabetes. Insulin secretion patterns could be a useful T2D predictor in the Chinese population (Journal of Diabetes and Its Complications)

Categories: News, Screening
Tags: insulin secretion, OGTT

Categories: Screening
Tags: insulin secretion, OGTT

One–hour post–load plasma glucose level during the OGTT predicts mortality: observations from the Israel Study of Glucose Intolerance, Obesity and Hypertension

March 21st 2016

A 1 h glucose value > 155 mg/dl predicts mortality even when the 2 h level is < 140 mg/dl. However, when the 2 h level is in the impaired glucose tolerance range, the hazard for mortality rises significantly independent of the 1 h value. Individuals at risk for developing diabetes could be identified earlier using the 1 h threshold value of 155 mg/dl, which could avert progression to diabetes and increased mortality (Diabetic Medicine)

Categories: Monitoring, News
Tags: OGTT

Categories: Monitoring
Tags: OGTT

Women with a history of gestational diabetes on long-term follow up have normal vascular function despite more dysglycemia, dyslipidemia and adiposity

October 12th 2015

Despite a higher incidence of adiposity, dyslipidemia, and impaired glycemia, women with a history of GDM who had a normal postpartum OGTT did not have impaired vascular function 4 to 10 years postpartum, when compared to healthy controls (Diabetes Research and Clinical Practice)

Categories: Gestational, News
Tags: dyslipidemia, OGTT, vascular function

Categories: Gestational
Tags: dyslipidemia, OGTT, vascular function

Smoking affects the oral glucose tolerance test profile and the relationship between glucose and HbA1c in gestational diabetes mellitus

September 30th 2015

In women with gestational diabetes mellitus who smoke at the beginning of pregnancy, the shape of the OGTT is consistent with accelerated glucose absorption, and HbA1c is higher than expected for glycaemic values (Diabetic Medicine)

Categories: Gestational, News
Tags: HbA1c, OGTT, smoking

Categories: Gestational
Tags: HbA1c, OGTT, smoking

Changing the protocol for gestational diabetes mellitus screening

July 23rd 2015

While early testing with OGTT for high-risk women may be helpful, the value of early testing with random BGL for low-risk women is questionable. The new ADIPS criteria are likely to increase the number of women diagnosed with GDM (with an emphasis on earlier diagnosis), but the absolute increase remains small  (Australian and New Zealand Journal of Obstetrics and Gynaecology)

Categories: Gestational, News
Tags: OGTT

Categories: Gestational
Tags: OGTT

The Discordance between HbA1c and Glucose Tolerance Testing for the Postpartum Exclusion of Diabetes following Gestational Diabetes

January 29th 2015

In the post-GDM population, the HbA1c misses cases of diabetes as identified by the OGTT. We recommend that the OGTT be retained for postpartum diabetes testing following GDM (Diabetes Research and Clinical Practice)

Categories: Gestational, News
Tags: HbA1c, OGTT

Categories: Gestational
Tags: HbA1c, OGTT

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