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Diabetes News

Tag: PIONEER


Efficacy and safety of oral semaglutide by subgroups of patient characteristics in the PIONEER phase 3 programme

April 5th 2022

Oral semaglutide demonstrated consistently greater HbA1c and body weight reductions across a range of patient characteristics, with greater HbA1c reductions seen at higher baseline HbA1c levels (Diabetes, Obesity and Metabolism)

Categories: Medication, News
Tags: HbA1c, PIONEER, semaglutide

Categories: Medication
Tags: HbA1c, PIONEER, semaglutide

Efficacy, Safety and Tolerability of Oral Semaglutide Versus Placebo Added to Insulin ± Metformin in Patients with Type 2 Diabetes: the PIONEER 8 Trial

September 17th 2019

Oral semaglutide was superior to placebo in reducing HbA1c and body weight when added to insulin ± metformin in patients with type 2 diabetes. The safety profile was consistent with other glucagon-like peptide-1 receptor agonists (Diabetes Care)

Categories: Medication, News
Tags: insulin, metformin, PIONEER, semaglutide

Categories: Medication
Tags: insulin, metformin, PIONEER, semaglutide

Oral Semaglutide versus Empagliflozin in Patients with Type 2 Diabetes Uncontrolled on Metformin: The PIONEER 2 Trial

September 17th 2019

Oral semaglutide was superior to empagliflozin in reducing HbA1c but not body weight at 26 weeks in patients with type 2 diabetes uncontrolled on metformin. At week 52, HbA1c and body weight (trial product estimand) were significantly reduced versus empagliflozin. Oral semaglutide was well tolerated within the established safety profile of GLP-1 receptor agonists (Diabetes Care)

Categories: Medication, News
Tags: Empagliflozin, PIONEER, semaglutide, Type 2 Diabetes

Categories: Medication
Tags: Empagliflozin, PIONEER, semaglutide, Type 2 Diabetes

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