This opinion piece explores existing definitions of diabetes remission and proposes a contemporary and comprehensive framework to help define this clinical state
Diabetes News
Tag: remission
Hypoglycemia during Short-Term Intensive Insulin Therapy and Its Association with Long-Term Glycemic Remission in Patients with Newly Diagnosed Type 2 Diabetes
Mild hypoglycemic episodes during the continuing insulin dose reduction period indicate a long-term drug-free euglycemic remission in patients with newly diagnosed type 2 diabetes. However, the insulin dosage should be reduced even more quickly in the future treatment to decrease the potential harms (Journal of Diabetes Research)
Lower Mean Blood Glucose during Short-term Intensive Insulin Therapy is Associated with Long-term Glycemic Remission in Patients with Newly Diagnosed Type 2 Diabetes: Evidence-based Recommendations for Standardization
Stricter glycemic control during short-term intensive insulin therapy produced more remission despite self-manageable hypoglycemia. Based on glycemic parameters in the middle mean tertile, we propose new glycemic targets that are about 0.4mmol/L lower than current ones as long-term benefit outweighs short-term risks (Journal of Diabetes Investigation)
Reconciliation of Type 2 Diabetes Remission Rates in Studies of Roux-en-Y Gastric Bypass
Variations in reported rates of diabetes remission after RYGB are primarily related to definitions and study duration. Future studies should report both cumulative and prevalent remission to aid decision making and more easily compare studies (Diabetes Care)
Type 2 Diabetes Remission Rates After Laparoscopic Gastric Bypass and Gastric Banding
Diabetes remission up to 3 years after RYGBP and LAGB was proportionally higher with increasing postsurgical weight loss. However, the nearly twofold greater weight loss–adjusted likelihood of diabetes remission in subjects undergoing RYGBP than LAGB suggests unique mechanisms contributing to improved glucose metabolism beyond weight loss after RYGBP (Diabetes Care)
Determinants of Diabetes Remission and Glycemic Control After Bariatric Surgery
The results show the advantage of an early operation together with better controlled glycemia on diabetes remission independently of BMI (Diabetes Care)
Clinical factors that predict remission of diabetes after different bariatric surgical procedures: interdisciplinary group of bariatric surgery of Verona (G.I.C.O.V.)
Bariatric surgical procedures that modify the upper gastrointestinal tract anatomy (RYBP and SG) are more successful in producing weight loss and remission of T2D than those that simply restrict stomach capacity (LAGB). Younger age, short duration of diabetes and better glucose control confer higher probability of achieving remission of diabetes (Acta Diabetologica)
Influence of Remission and its Duration on Development of Early Microvascular Complications in Young Adults With Type 1 Diabetes
Occurrence of partial remission of diabetes is associated with a reduced risk of chronic microvascular complications at 7-year follow-up (Journal of Diabetes and Its Complications)
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