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Diabetes News

Tag: retinopathy


Association of Abnormal Renal Profiles and Proliferative Diabetic Retinopathy and Diabetic Macular Edema in an Asian Population With Type 2 Diabetes

November 28th 2017

Abnormal renal profiles at baseline, including a high serum creatinine level, low estimated glomerular filtration rate, and high urinary ACR, were associated with the development of PDR in patients with type 2 diabetes (JAMA Ophthalmology)

Categories: News, Ophthalmology
Tags: Abnormal Renal Profiles, Asian, macular edema, retinopathy, Type 2 Diabetes

Categories: Ophthalmology
Tags: Abnormal Renal Profiles, Asian, macular edema, retinopathy, Type 2 Diabetes

The UK Diabetic Retinopathy Electronic Medical Record (UK DR EMR) Users Group, Report 2: real-world data for the impact of cataract surgery on diabetic macular oedema

November 23rd 2017

This large real-world study demonstrates that the rate of developing treatment-requiring DMO increases sharply in the year after cataract surgery for all grades of retinopathy, peaking in the 3–6 months’ postoperative period. Patients with moderate and severe NPDR are at particularly high risk (British Journal of Ophthalmology)

Categories: News, Ophthalmology
Tags: cataract surgery, diabetic retinopathy, retinopathy

Categories: Ophthalmology
Tags: cataract surgery, diabetic retinopathy, retinopathy

Mechanism of worsening diabetic retinopathy with rapid lowering of blood glucose: the synergistic hypothesis

October 11th 2017

We postulate that exogenous insulin could act synergistically with the vascular endothelial growth factor expressed by ischemic retina so as to trigger vascular proliferation and the worsening of diabetes retinopathy (BMC Endocrine Disorders)

Categories: News, Ophthalmology
Tags: retinopathy

Categories: Ophthalmology
Tags: retinopathy

Insulin resistance correlates with maculopathy and severity of retinopathy in young adults with Type 1 Diabetes Mellitus

June 28th 2017

IR correlates with more severe retinopathy in young adults with Type 1 DM. This is the first description of a correlation between IR and maculopathy in Type 1 DM, warranting further evaluation. Prospective studies examining whether reducing IR can improve microvascular complications are required (Diabetes Research and Clinical Practice)

Categories: News, Ophthalmology
Tags: Insulin resistance, retinopathy, Type 2 Diabetes

Categories: Ophthalmology
Tags: Insulin resistance, retinopathy, Type 2 Diabetes

Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks

May 8th 2017

Patients with proliferative diabetic retinopathy who were treated with intravitreal aflibercept had an improved outcome at 1 year compared with those treated with PRP standard care (Lancet)

Categories: News, Ophthalmology
Tags: aflibercept, retinopathy

Categories: Ophthalmology
Tags: aflibercept, retinopathy

Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes

April 20th 2017

Our model for establishing an individualized schedule for retinopathy screening on the basis of the patient’s current state of retinopathy and glycated hemoglobin level reduced the frequency of eye examinations without delaying the diagnosis of clinically significant disease (NEJM)

Categories: News, Ophthalmology
Tags: retinopathy, Type 1 Diabetes

Categories: Ophthalmology
Tags: retinopathy, Type 1 Diabetes

The English National Screening Programme for diabetic retinopathy 2003–2016

February 22nd 2017

The benefit of the programme is that, in England, diabetic retinopathy/maculopathy is no longer the leading cause of certifiable blindness in the working age group (Acta Diabetologica)

Categories: News, Ophthalmology
Tags: retinopathy, screening

Categories: Ophthalmology
Tags: retinopathy, screening

Diabetic Retinopathy

February 22nd 2017

A Position Statement by the American Diabetes Association (Diabetes Care)

Categories: News, Ophthalmology
Tags: retinopathy

Categories: Ophthalmology
Tags: retinopathy

Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs

December 6th 2016

In this evaluation of retinal fundus photographs from adults with diabetes, an algorithm based on deep machine learning had high sensitivity and specificity for detecting referable diabetic retinopathy (JAMA)

Categories: News, Ophthalmology
Tags: AI, retinopathy

Categories: Ophthalmology
Tags: AI, retinopathy

Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy A Randomized Clinical Trial

November 24th 2015

Among eyes with proliferative diabetic retinopathy, treatment with ranibizumab resulted in visual acuity that was noninferior to (not worse than) PRP treatment at 2 years. Although longer-term follow-up is needed, ranibizumab may be a reasonable treatment alternative, at least through 2 years, for patients with proliferative diabetic retinopathy (JAMA)

Categories: News, Ophthalmology
Tags: ranibizumab, retinopathy

Categories: Ophthalmology
Tags: ranibizumab, retinopathy

Cross Talk between Lipid Metabolism and Inflammatory Markers in Patients with Diabetic Retinopathy

July 29th 2015

It seems that there is a link between metabolic and inflammatory markers. Apo-B/Apo-A ratio should be evaluated as a reliable risk factor for PDR and CSME, while the role of increased systemic TNF-α and VEGF should be explored in CSME (Journal of Diabetes Research)

Categories: News, Ophthalmology
Tags: retinopathy

Categories: Ophthalmology
Tags: retinopathy

Significance of the antiangiogenic mechanisms of thalidomide in the therapy of diabetic retinopathy

July 24th 2015

Amongst several antiangiogenic agents, thalidomide holds a reputable position due to its effectiveness in terminating angiogenesis during various pathological conditions. This review focuses on the diverse molecular mechanisms proposed to explain the antiangiogenic properties of thalidomide and their applicability in diabetic retinopathy (Vascular Pharmacology)

Categories: News, Ophthalmology
Tags: retinopathy

Categories: Ophthalmology
Tags: retinopathy

Combined Methods for Diabetic Retinopathy Screening, Using Retina Photographs and Tear Fluid Proteomics Biomarkers

June 29th 2015

As the two different types of data represent independent and complementary information on the outcome, the combined model resulted in a reliable screening method that is comparable to the requirements of DR screening programs applied in clinical routine (Journal of Diabetes Research)

Categories: News, Ophthalmology, Screening
Tags: retinopathy

Categories: Ophthalmology, Screening
Tags: retinopathy

Diabetic Retinopathy in Pregnancy: A Population-Based Study of Women with Pregestational Diabetes

April 6th 2015

This study highlights the role of prepregnancy care and the importance of close monitoring during pregnancy and identifies those patients at the highest risk for retinopathy progression (Journal of Diabetes Research)

Categories: News, Ophthalmology
Tags: pregnancy, retinopathy

Categories: Ophthalmology
Tags: pregnancy, retinopathy

FDA approves new treatment for diabetic retinopathy in patients with diabetic macular edema

March 25th 2015

The U.S. Food and Drug Administration expand the approved use for Eylea (aflibercept) injection to treat diabetic retinopathy in patients with diabetic macular edema

Categories: News, Ophthalmology
Tags: aflibercept, macular edema, retinopathy

Categories: Ophthalmology
Tags: aflibercept, macular edema, retinopathy

Social deprivation as a risk factor for late presentation of proliferative diabetic retinopathy

March 4th 2015

In our cohort social deprivation appears to be associated with late presentation of proliferative diabetic retinopathy. Our study supports the need to target these groups to reduce preventable blindness and to identify strategies which overcome barriers to care (Clinical Ophthalmology)

Categories: News, Ophthalmology
Tags: retinopathy

Categories: Ophthalmology
Tags: retinopathy

A classification model for predicting eye disease in newly diagnosed people with type 2 diabetes

March 2nd 2015

A classification model using readily available patient information and routine biochemical measures can be used to identify patients at high risk of having retinopathy at the time their diabetes is diagnosed; The model may be used to identify high-risk patients for retinopathy screening (Diabetes Research and Clinical Practice)

Categories: News, Ophthalmology
Tags: retinopathy

Categories: Ophthalmology
Tags: retinopathy
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