To ensure these systems are well poised to deliver the promise of more targeted control, it is essential to understand the unique characteristics and factors of childhood (Diabetes Care)
Diabetes News
Glycosmedia is dedicated to bringing free, non-promotional, editorially independent news to a global audience about developments in diabetes, and is primarily aimed at health professionals.
SGLT2 Inhibitors in Combination Therapy: From Mechanisms to Clinical Considerations in Type 2 Diabetes Management
With guidelines moving away from a one-size-fits-all approach toward setting patient-centered goals and allowing flexibility in choosing a second-/third-line drug from the growing number of U.S. Food and Drug Administration–approved glucose-lowering agents, keen personalized management in T2D has become a challenge for health care providers in daily practice (Diabetes Care)
Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study
Sulfonylureas as second line drugs are associated with an increased risk of myocardial infarction, all cause mortality, and severe hypoglycaemia, compared with remaining on metformin monotherapy. Continuing metformin when introducing sulfonylureas appears to be safer than switching (BMJ)
Uptake and retention in group-based weight-management services
Literature review and behavioural analysis (Public Health England)
Diabetic Gastroparesis
This editorial addresses the importance of diabetic gastroparesis as a marker of poor glycemic control, other vascular complications, and suboptimal therapeutic outcomes (Diabetes Therapy)
Interactions between and Shared Molecular Mechanisms of Diabetic Peripheral Neuropathy and Obstructive Sleep Apnea in Type 2 Diabetes Patients
In this review, we seek to illuminate the relationships among T2D, diabetic peripheral neuropathy, and OSA and how they interact with one another (Journal of Diabetes Research)
Performance of Cardiovascular Disease Risk Scores in People Diagnosed With Type 2 Diabetes: External Validation Using Data From the National Scottish Diabetes Register
None of the risk scores performed well among people with newly diagnosed type 2 diabetes. Using these risk scores to predict 5-year CVD risk in this population may not be appropriate (Diabetes Care)
Impact of acute diabetes decompensation on outcomes of diabetic patients admitted with ST-elevation myocardial infarction
Decompensated diabetes complicates ~ 1.5% of STEMI admissions in diabetic patients. It is associated with lower rates of referral for angiography and revascularization, and a negative differential impact on in-hospital morbidity and mortality and cost (Diabetology & Metabolic Syndrome)
Efficacy of Low-Level Light Therapy for Treatment of Diabetic Foot Ulcer
LLLT was recognized as a potential method in the comprehensive treatment of DFUs. Further well designed and high-quality studies are required to confirm the role of LLLT in the management of DFUs (Diabetes Research and Clinical Practice)
A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk
The T1D GRS independently predicts progression to T1D and improves prediction along T1D stages in autoantibody-positive relatives (Diabetes Care)
Novel therapies for diabetes mellitus in pregnancy
This article will review recent clinical studies to summarize established treatment strategies and introduce novel therapies for diabetes in pregnancy (BMJ)
The All-Cause Mortality and a Screening Tool to Determine High-Risk Patients among Prevalent Type 2 Diabetes Mellitus Patients
The model has moderate accuracy; the prognostic model can be used as a screening tool to classify T2DM patients who are at higher risk for mortality within five years (Journal of Diabetes Research)
SGLT2 Inhibitors and Cardiovascular Outcomes: Current Perspectives and Future Potentials
Though more data is needed to substantiate the safety and efficacy, SGLT2i should be considered as a valuable therapy to help reduce CV risk in patients with diabetes. Ultimately, SGLT2i may have utility in preventing progression to diabetes or providing CV protection in patients who do not have diabetes (Current Diabetes Reports)
Visit-to-visit HbA1c variability is inversely related to baroreflex sensitivity independently of HbA1c value in type 2 diabetes
Visit-to-visit HbA1c variability was inversely related to BRS independently of the mean HbA1c in patients with T2DM. Therefore, visit-to-visit HbA1c variability might be a marker of reduced BRS in T2DM (Cardiovascular Diabetology)
Risk-Factor Trajectories Preceding Diabetic Polyneuropathy: ADDITION-Denmark
Both higher levels and slopes of HbA1c trajectories were associated with DPN after 13 years. Our findings indicate that the rate of HbA1c increase affects the development of DPN over and above the effect of the HbA1c level. Furthermore, this study supports obesity as a risk factor for DPN (Diabetes Care)
Global perspectives on the provision of diabetic retinopathy screening and treatment: Survey of health care professionals in 41 countries
Health care professionals need to be appropriately supported and trained so they can provide adults with diabetes with information about the risks of DR, support them in reducing their risk, and advocate for the provision of affordable DR screening and treatment as required (Diabetes Research and Clinical Practice)
Young people’s experiences of managing Type 1 diabetes at university: a national study of UK university students
The study quantifies the high level of risk experienced by students with Type 1 diabetes during the transition to university, in particular, female students and those moving to a new university healthcare provider (Diabetic Medicine)
Determinants of 20‐year non‐progression to Type 2 diabetes in women at very high risk: the E3N cohort study
We showed that the top characteristic associated with not developing Type 2 diabetes, despite being at very high risk, was a healthy diet, characterized by limiting Western dietary habits, but with a high intake of antioxidant‐rich foods (Diabetic Medicine)
FRAX tool in type 2 diabetic subjects: the use of HbA1c in estimating fracture risk
We propose a correction factor derived from HbA1c that could enhance the predictive ability of fracture risk estimated by the FRAX algorithm in subjects with T2DM (Acta Diabetologica)
Factors associated with type 2 diabetes in patients with vascular dementia: a population-based cross-sectional study
The findings of this study suggest that clinicians should encourage patients with dementia to receive regular glucose impairment screening if they are female, have low socioeconomic status, or have renal or metabolic diseases (BMC Endocrine Disorders)
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