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Diabetes News

Glycosmedia is dedicated to bringing free, non-promotional, editorially independent news to a global audience about developments in diabetes, and is primarily aimed at health professionals.


Glycemic Control after Treatment Intensification in Patients with Type 2 Diabetes Uncontrolled on Two or More Non‐Insulin Antidiabetic Drugs in a Real‐World Setting

February 13th 2019

Despite intensification, most patients failed the glycaemic goal of HbA1c <7%. The reduction depended mainly on pre‐intensification HbA1c values, with small differences between drugs (Diabetes, Obesity and Metabolism)

Categories: News, Treatment
Tags: Type 2 Diabetes

Categories: Treatment
Tags: Type 2 Diabetes

Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013: a multicentre prospective registration study

February 13th 2019

Despite reductions in the rate of increase in some high-risk countries, the pooled estimate across centres continues to show a 3.4% increase per annum in incidence rate, suggesting a doubling in incidence rate within approximately 20 years in Europe (Diabetologia)

Categories: News, Prevalence
Tags: Europe, Type 1 Diabetes

Categories: Prevalence
Tags: Europe, Type 1 Diabetes

The Standard of Care in Type 2 Diabetes: Re-evaluating the Treatment Paradigm

February 13th 2019

The symposium, while acknowledging the need for newer antidiabetic drugs in specific situations and patient groups, recommended the continuation of SUs and metformin as the primary oral antidiabetic agents in resource-constrained regions of the world (Diabetes Therapy)

Categories: News, Treatment
Tags: Type 2 Diabetes

Categories: Treatment
Tags: Type 2 Diabetes

Preventing misdiagnosis of diabetes in the elderly: age-dependent HbA1c reference intervals derived from two population-based study cohorts

February 12th 2019

The present study confirmed the previously observed increase of HbA1c with increasing age in non-diabetic individuals. As a consequence age-dependent reference values for HbA1c were derived from two large and well defined reference populations. Implementation of them into daily practice may improve patient care and diagnosis of diabetes and reduce the risk of misdiagnosis and subsequent overtreatment of diabetes in elderly patients (BMC Endocrine Disorders)

Categories: News, Screening
Tags: elderly, HbA1c

Categories: Screening
Tags: elderly, HbA1c

The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes

February 12th 2019

Elevated NGAL relates to intrarenal haemodynamic dysfunction in T1D, whereas elevated NGAL and B2M relate to intrarenal haemodynamic dysfunction in adults without T1D. These data may define a diabetes‐specific interplay between tubular injury and intrarenal haemodynamic dysfunction (Diabetes, Obesity and Metabolism)

Categories: Nephropathy, News
Tags: tubular injury, Type 1 Diabetes

Categories: Nephropathy
Tags: tubular injury, Type 1 Diabetes

Medical devices: information for users and patients

February 11th 2019

Including blood glucose meters (NICE)

Categories: Monitoring, News
Tags: meters, NICE

Categories: Monitoring
Tags: meters, NICE

Perceptions of insulin therapy in people with type 2 diabetes and physicians: a cross-sectional survey conducted in France

February 11th 2019

Most people with T2D reported that transitioning to insulin therapy was less difficult than they had feared. People with T2D and physicians exhibited differing perceptions regarding the transition (Patient Preference and Adherence)

Categories: Management, News
Tags: insulin, Type 2 Diabetes

Categories: Management
Tags: insulin, Type 2 Diabetes

The effect of short-term intensive insulin therapy on circulating T cell subpopulations in patients with newly diagnosed type 2 diabetes mellitus

February 11th 2019

Short-term intensive insulin therapy could modulate circulating T cell subpopulations in patients with T2DM, which might alleviate inflammatory responses caused by hyperglycemia

Categories: Medication, News
Tags: insulin, T cell, Type 2 Diabetes

Categories: Medication
Tags: insulin, T cell, Type 2 Diabetes

Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study

February 11th 2019

During DCCT/EDIC, higher insulin doses were associated with adverse trends in several cardiometabolic risk factors, even after multivariable adjustment, but not with incident CVD outcomes (Diabetes Care)

Categories: News, Treatment
Tags: cardiometabolic risk, insulin, Type 1 Diabetes

Categories: Treatment
Tags: cardiometabolic risk, insulin, Type 1 Diabetes

Text‐message responsiveness to blood glucose monitoring reminders is associated with HbA1c benefit in teenagers with Type 1 diabetes

February 8th 2019

Teenagers with Type 1 diabetes who responded to text reminders on ≥50% of days over 18 months experienced clinically significant glycaemic benefit. There remains a need to tailor interventions to maintain teenager engagement and optimize improvements (Diabetic Medicine)

Categories: Monitoring, News
Tags: HbA1c, text messaging, Type 1 Diabetes

Categories: Monitoring
Tags: HbA1c, text messaging, Type 1 Diabetes

Glycemic Variability Is a Powerful Independent Predictive Factor of Midterm Major Adverse Cardiac Events in Patients With Diabetes With Acute Coronary Syndrome

February 8th 2019

A GV cutoff value of >2.70 mmol/L was the strongest independent predictive factor for midterm MACE in patients with diabetes and ACS  (Diabetes Care)

Categories: Cardiovascular, News
Tags: glycemic variability

Categories: Cardiovascular
Tags: glycemic variability

International Consensus on Risk Management of Diabetic Ketoacidosis in Patients with Type 1 Diabetes Treated with Sodium-Glucose Cotransporter (SGLT) Inhibitors

February 7th 2019

This consensus report reviews current data regarding SGLT- inhibitor use and provides recommendations to enhance the safety of SGLT-inhibitors in people with type 1 diabetes (Diabetes Care)

Categories: Medication, News
Tags: Ketoacidosis, SGLT2 inhibitors

Categories: Medication
Tags: Ketoacidosis, SGLT2 inhibitors

Validation of low-cost smartphone-based thermal camera for diabetic foot assessment

February 7th 2019

The smartphone-based IR-camera shows excellent validity for diabetic foot assessment (Diabetes Research and Clinical Practice)

Categories: Monitoring, News
Tags: foot, smartphone-based

Categories: Monitoring
Tags: foot, smartphone-based

Incretin-Based Antihyperglycemic Agents for the Management of Acute Ischemic Stroke in Patients with Diabetes Mellitus: A Review

February 6th 2019

Several preclinical studies consistently showed that GLP-1 receptor agonists reduce infarct volume and improve the functional outcome after ischemic stroke. These beneficial effects appear to be mediated by anti-inflammatory, antioxidant, and anti-apoptotic actions of these agents (Diabetes Therapy)

Categories: News, Treatment
Tags: GLP1, stroke

Categories: Treatment
Tags: GLP1, stroke

Participants’ Experiences of, and Views About, Daytime Use of a Day-and-Night Hybrid Closed-Loop System in Real Life Settings

February 6th 2019

While participants reported substantial benefits to using the closed loop during the day, they also identified ways in which the technology could be refined and education and training tailored to optimize effective use. Our findings suggest that mainstreaming this technology will not necessarily lead to increased demands on clinical staff (Diabetes Technology and Therapeutics)

Categories: News, Treatment
Tags: closed-loop

Categories: Treatment
Tags: closed-loop

The association between Gestational Diabetes and Postpartum Depression: A Systematic Review and Meta-analysis

February 6th 2019

The association between Gestational Diabetes and Postpartum Depression: A Systematic Review and Meta-analysis (Diabetes Research and Clinical Practice)

Categories: Gestational, News
Tags: depression, postpartum

Categories: Gestational
Tags: depression, postpartum

Nomogram for predicting diabetes mellitus after the first attack of acute pancreatitis

February 6th 2019

The nomogram is a potentially clinically useful tool for predicting new-onset diabetes, which is currently clinically unprecedented. This finding is not confined to the patients with severe AP but is also for patients who have recovered from mild AP. The nomogram must to be validated externally (European Journal of Gastroenterology & Hepatology)

Categories: News, Screening
Tags: nomogram

Categories: Screening
Tags: nomogram

Cutaneous microangiopathy in patients with type 2 diabetes: impaired vascular endothelial growth factor expression and its correlation with neuropathy, retinopathy and nephropathy

February 5th 2019

This study is the first report to demonstrate that cutaneous microangiopathy, as indicated by subepidermal microvascular proliferation and impaired VEGF expression, appears to occur prior to the development of overt clinical neuropathy, retinopathy or nephropathy in patients with type 2 diabetes (Journal of Diabetes Investigation)

Categories: Monitoring, News
Tags: microangiopathy, Type 2 Diabetes

Categories: Monitoring
Tags: microangiopathy, Type 2 Diabetes

Effect of Remote Glucose Monitoring Utilizing Computerized Insulin Dose Adjustment Algorithms: A Pilot Project

February 5th 2019

Remote glucose monitoring utilizing computerized insulin dose adjustment algorithms saved time for both providers and patients while effectively improving glycemia (Diabetes Therapy)

Categories: News, Treatment
Tags: remote monitoring

Categories: Treatment
Tags: remote monitoring

Heart failure among people with Type 2 diabetes mellitus: real‐world data of 289 954 people from a diabetes database

February 4th 2019

Heart failure is common in diabetes mellitus, but the prevalence in the DPV is lower frequent than expected. The reason for improved metabolic control in heart failure may be intensified therapy with insulin, lipid‐lowering medication and anti‐hypertensives in this cohort (Diabetic Medicine)

Categories: Cardiovascular, News
Tags: heart failure, insulin, Type 2 Diabetes

Categories: Cardiovascular
Tags: heart failure, insulin, Type 2 Diabetes
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