Cognitive Function and Brain Structure in Persons With T2D Mellitus After Intensive Lowering of Blood Pressure and Lipid Levels

In participants with long-standing T2DM and at high risk for cardiovascular events, intensive BP control and fibrate therapy in the presence of controlled low-density lipoprotein cholesterol levels did not produce a measurable effect on cognitive decline at 40 months of follow-up. Intensive BP control was associated with lower decline in TBV at 40 months relative to standard therapy (JAMA Internal Medicine)