Diabetes News March 12th 2010

Safe and effective use of insulin in hospitalised patients
The purpose of this document is to consider the evidence and to make recommendations for trusts to follow to ensure that insulin is used effectively and safely (NHS Diabetes)

The hospital management of hypoglycaemia in adults with diabetes mellitus
The aim of this guidance is to advise on the the prompt and effective treatment and hospital management of hypoglycaemia in adults with diabetes mellitus (NHS Diabetes)

The management of diabetic ketoacidosis in adults
These guidelines have been developed to reflect the development in technology and reflect new practice in the management of DKA in the UK (NHS Diabetes)

Emotional and psychological support and care in diabetes
This NHS Diabetes report explores the many issues relevant to integrating emotional and psychological care within diabetes services (NHS Diabetes)

Guideline on self-monitoring of blood glucose in non-insulin treated type 2 diabetes
(International Diabetes Federation)

Guideline on oral health for people with diabetes
(International Diabetes Federation)

Global guideline on pregnancy and diabetes
(International Diabetes Federation)

Long-acting insulin analogs and the risk of diabetic ketoacidosis in children and adolescents with type 1 diabetes
Despite their long-acting pharmacokinetics, the use of insulin glargine or detemir is not associated with a lower incidence of DKA compared to NPH insulin (Diabetes Care)

Type 2 diabetes: postprandial hyperglycemia and increased cardiovascular risk
Target levels of glucose control should be individualized by focusing on both FPG and PPG and by optimizing other risk factors of CVD, including high blood pressure, hyperlipidemia, obesity, smoking, and poor exercise and dietary habits (Vascular Health and Risk Management)

A Cardiologist’s View of Hypoglycemia
In this article, we review the physiology of glucose metabolism, the cardiovascular pathophysiology of hypoglycemia, and the trials with an intensive glucose-lowering strategy that have studied microvascular and macrovascular complications (Current Atherosclerosis Reports)

Reducing the risk of fatal and disabling hypoglycaemia: a comparison of arterial blood sampling systems
Our study demonstrates that the closed-loop arterial sampling system could be the universal solution sought by the National Patient Safety Agency (British Journal of Anaesthesia)

DLife Members Show Increased Use of Prescription Drugs to Treat Diabetes
Diabetes patients who use the multimedia network dLife increased their use of prescription diabetes drugs by 1,600 percent compared with non-users (American Diabetes Association)

Surprising findings about Hepatitis C and insulin resistance
Researchers at Garvan have now confirmed the link between Hepatitis C and Type 2 diabetes – people with the virus being 3 to 4 times more likely to develop diabetes, owing to high levels of insulin resistance in muscle (Garvan Institute of Medical Research)

Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus Trial
Bristol-Myers Squibb and AstraZeneca Announce the Commencement of the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus Trial (Market Watch)

Diamyd US Phase III study well under way
The study will include 320 children and adolescents between 10 and 20 years of age, recently diagnosed with type 1 diabetes (Diamyd)

Diabetes Device Manufacturers Face New Regulations
A U.S. Food and Drug Administration push for more accurate blood glucose meters for managing diabetes has caught the attention of local device makers and developers testing next-generation products (San Diego Business Journal)

Generex Oral-lyn
Generex Establishes Key Strategic Relationships for the Development of a Distribution Network for Generex Oral-lyn under the FDA’s Expanded Access Treatment IND Program (PharmaLive)