Diabetes News March 4th 2009

Diabulimia: What It Is and How To Treat It
Diabulimia is an eating disorder in which people with type 1 diabetes deliberately give themselves less insulin than they need for the purpose of weight loss (Diabetes Health)

Insulinomatosis: A Multicentric Insulinoma Disease that Frequently Causes Early Recurrent Hyperinsulinemic Hypoglycemia
Insulinomatosis is characterized by the synchronous and metachronous occurrence of insulinomas, multiple insulinoma precursor lesions, and rare development of metastases, but common recurrent hypoglycemia. This disease differs from solitary sporadic and MEN1-associated insulinomas (American Journal of Surgical Pathology)

Over-representation of diabetic patients with renal anaemia in the primary care setting
Diabetic patients were more likely to have NICE defined renal anaemia in this primary care population with CKD stages 3–5. This is similar to observations in secondary care settings (Family Practice)

Diabetes Incidence Based on Linkages with Health Plans: The Multiethnic Cohort
Within this multiethnic population, diabetes incidence was two-fold higher among Japanese Americans and Native Hawaiians than Caucasians. The highly significant interaction of ethnicity with BMI and education suggest ethnic differences in diabetes etiology (Diabetes)

Children with diabetes ‘need more NHS help’
The growing numbers of children with obesity-related diabetes need more radical help from the NHS if they are to have any chance of a normal, healthy life, according to experts (Guardian, UK)

AstraZeneca tried to ‘bury’ bad news on Seroquel drug
The Anglo-Swedish drugs group is being sued by a total of 9,200 patients, most of whom allege that the Seroquel treatment for psychiatric disorders gave them diabetes (Times, UK)

The geospatial relation between UV solar radiation and type 1 diabetes in Newfoundland
This study suggests that erythemal UVB radiation may be geospatially associated with the incidence of T1DM in Newfoundland (Acta Diabetologica)

Insulin drug study shows significant improvements in more than 52,000 diabetic patients
A major international diabetes study of more than 52,000 patients from eight countries has shown that using biphasic BIAsp 30 insulin resulted in significant clinical improvements and greater patient satisfaction (EurekAlert)

Insulin-induced weight gain and cardiovascular events in patients with type 2 diabetes. A report from the DIGAMI 2 study
Initiation of insulin treatment after myocardial infarction was associated with a significant increase in weight and incidence of reinfarction. The increase in weight did, however, not explain the increased rate of reinfarction (Diabetes, Obesity and Metabolism)

Generex Oral-lyn™ to be presented at International Conference on Advances in Diabetes and Insulin Therapy
Professor Pozzilli will present his paper entitled Buccal Spray Insulin for Treatment of Diabetes. The paper concludes that Generex Oral-lyn is able to control plasma glucose as well as fast-acting injectable insulin analogs (lispro, aspart, glulisine) and can be used to control post-prandial hyperglycaemia (Business Wire)

NZSSD Position Statement on standardisation of reporting units for HbA1c and application of estimated average glucose (eAG)
New Zealand clinical laboratories should implement dual reporting of HbA1c in both molar units (mmol/mol) and currently reported DCCT-aligned units (%), as recommended in a consensus statement from ADA, EASD, IFCC and IDF, published in 2007. After a period of two years from the time of implementation it is envisaged that only molar units will be reported (NZSSD)

The disease that’s stalking my children, by BBC newsman Justin Webb
He didn’t cry much. We did it for him (Daily Mail)

TOPDOC Diabetes Study
The TOPDOC Diabetes Study (Trainees Own Perception of Delivery Of Care in Diabetes) – This is a national study of confidence levels amongst trainee doctors in the management of diabetes. It takes only 5 minutes to complete the survey (TOPDOC, USA)

Diabetes distress and its association with clinical outcomes in patients with type 2 diabetes treated with pramlintide as an adjunct to insulin therapy
Pramlintide use reduced diabetes-related distress among those with high levels of distress at baseline, and better clinical outcomes were associated with improvements in several domains of diabetes-related distress (PubMed)

Emotional, Not Just Physical Weight, Increases Type 2 Diabetes Risk
The combination of stress and obesity may significantly influence the development of type 2 diabetes among African-American women, with stress having a potentially greater role, according to researchers from Duke University Medical Center (insciences)

Trends in laboratory testing for diabetes in Ontario, Canada 1995-2005: A population-based study
Diabetes testing is common and has increased over the last ten years. Despite its absence in Canada’s diabetes screening recommendations, HbA1c testing among individuals without diabetes is increasing rapidly, and OGTT, which is recommended, is rarely performed (BMC Health Services Research)

Novel Noninvasive Breath Test Method for Screening Individuals at Risk for Diabetes
These results suggest that this novel breath test method may assist in recognition of pre-diabetes or early-stage diabetes in at-risk persons without the need for invasive blood sampling, thus making it an attractive option for large-scale testing of at-risk populations, such as children (Diabetes Care)

GI News
March edition (GI News)