Teens’ Faculties Not Harmed by Low Blood Sugar
Teenagers with type 1 diabetes who aim to keep their glucose levels under tight control may have frequent episodes of too-low blood sugar, but this apparently has no lasting effect on their cognitive function (American Diabetes Association)
Targeting Blood Glucose Management in School Improves Glycemic Control in Children with Poorly Controlled Type 1 Diabetes Mellitus
Average HbA1c was lowered by 1.6%, suggesting that this intervention helps this difficult group of patients (Clinical and Laboratory Observation)
In Vivo Insulin Sensitivity and Secretion in Obese Youth: What are the Differences between NGT, IGT and Type 2 Diabetes?
Data suggest that measures to prevent progression or conversion from pre-diabetes to T2DM should target improvement in beta-cell function (PubMed)
Diabetes costs NHS £1 million per hour
A report published by Diabetes UK confirms that diabetes is one of the biggest health challenges facing the UK (Diabetes UK)
HbA1c of at least 6.1% can identify patients with undiagnosed diabetes
At-risk individuals with an HbA1c test level >=6.1% are more likely to have undiagnosed diabetes, according to new study findings (Endocrine Today)
The Darkening Cloud of Diabetes: Do Trends in Cardiovascular Risk Management Provide a Silver Lining?
During our period of study, there was an increase in the utilization of evidenced based drug therapies in people with diabetes and reductions in cardiovascular-related hospitalizations. Despite this, we observed no change in all-cause mortality (Diabetes Care)
Update 2008
The autumn edition of the Update magazine is now available for download (Diabetes UK)
International tables of glycemic index and glycemic load values: 2008
The tables list the GI of over 2,480 individual food items (Diabetes care)
The Crosstalk Between Insulin and Renin-Angiotensin-Aldosterone Signaling Systems and its Effect on Glucose Metabolism and Diabetes Prevention
This review will discuss: a) the molecular mechanisms of the crosstalk between the insulin and angiotensin II signaling systems b) the results of clinical studies employing drugs targeting the renin-angiotensin IIaldosterone systems and their role in glucose metabolism and diabetes prevention (Current Vascular Pharmacology)
Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes
Evaluation of a large number of statistical GWA candidates in several independent cohorts has revealed additional loci that are associated with T1D (Diabetes)
The clinical relevance of assessing advanced glycation endproducts accumulation in diabetes
This review article will focus on the clinical relevance of measuring advanced glycation endproducts (AGE) accumulation in diabetic patients by focusing on AGE formation, AGEs as predictors of long-term complications, and interventions against AGEs (Cardiovascular Diabetology)
Effect of weight-reducing agents on glycaemic parameters and progression to Type 2 diabetes: a review
This review summarizes evidence from 23 placebo-controlled randomized trials, of at least 1 year duration, on the effects of drugs promoting weight loss (orlistat, sibutramine and rimonabant) on glycaemic variables, diabetes incidence and diabetes control (Diabetic Medicine)
Cost of obesity to local health services revealed
New figures out today show, for the first time, the cost of obesity to every Primary Care Trust in England (NHS, UK)
Islet Specific Wnt Activation in Human Type 2 Diabetes
Large PDF download available (Experimental Diabetes Research)
Beware the silent assassin – Diabetes UK launches hard-hitting ad campaign
The advertising campaign, developed by The Gate, will include a series of outdoor posters as well as newspaper and consumer magazine advertising during October and November 2008 (Diabetes UK)
CD28/CD154 Blockade Prevents Autoimmune Diabetes by Inducing Nondeletional Tolerance After Effector T-Cell Inhibition and Regulatory T-Cell Expansion
Immunotherapies that selectively suppress effector T-cells while permitting the development of natural regulatory mechanisms may have a unique role in establishing targeted long-standing immune protection and peripheral tolerance (Diabetes)
Postpartum Screening for Diabetes After a Gestational Diabetes Mellitus–Affected Pregnancy
Postpartum glucose testing in women with GDM-affected pregnancies increased over time. However, even in recent years, 42% of women with GDM-affected pregnancies failed to have a postpartum FPG test, and no test was ordered for 21% of GDM-affected pregnancies (Obstetrics & Gynecology)
Prevalence of abnormal glucose metabolism in atrial fibrillation: a case control study in 75-year old subjects
Atrial fibrillation is associated with chronic hyperglycaemia amongst 75-year old subjects. Prediabetes and DM should be pro-actively assessed if AF duration >= 5 years (Cardiovascular Diabetology)
VIVUS Announces the Weight Loss Effects of Qnexa in Type 2 Diabetes
Presentation at the Obesity Society Annual Scientific Meeting Shows Weight Loss of 17 Pounds in 28 Weeks (MarketWatch)
A diet pill? Put it down to fat chance
A collaboration between six Melbourne institutions could result in a pill that eliminates obesity and diabetes (The Age, Australia)
iSense and Their “Glycemic Signature”
What’s new and different with the iSense system versus the current CGM models that have recently hit the market are two things: the special flexible micro-wire technology of their sensor, and the sophisticated data reporting system they’re developing, which they call The Glycemic Signature (Diabetes mine)
The relationship between fasting hyperglycemia and insulin secretion in subjects with normal or impaired glucose tolerance
Small increments in FPG, within the “normal” range, are associated with a marked decline in glucose-stimulated insulin secretion and the decrease in insulin secretion with increasing FPG is greater in subjects with NGT than IGT and primarily is due to a decline in early-phase insulin secretion (PubMed)
Fasting insulin is a stronger cardiovascular risk factor in women than in men
In parallel with diabetes, fasting hyperinsulinaemia reflecting insulin resistance in non-diabetic subjects is associated with an increased risk for cardiovascular disease, which is more pronounced in women than in men (PubMed)
Diabetes UK backs National Diabetes Audit in Wales
Diabetes UK Cymru is encouraging GPs’ surgeries to follow the example of paediatric centres in Wales and take part in the National Diabetes Audit (Diabetes UK)
Diabetes Forecast Takes a Look Back and a Step Forward
For 60 years, Diabetes Forecast, the consumer magazine of the American Diabetes Association (ADA), has been bringing crucial information to people with diabetes. The October issue celebrates the magazine’s 60th anniversary with a major redesign that takes on a more contemporary look and includes new features on research, nutrition, and treatment (Market Watch)
F as in Fat
How obesity policies are failing in America. 144-page PDF (The Trust for America’s Health)
Improving treatment for those with both diabetes and mental health
With those who have a mental illness more likely to have type-2 diabetes, health workers across SA are meeting to discuss improving treatment and prevention (Department of Health, Australia)
Pattern of 24-hour ambulatory blood pressure monitoring in type 2 diabetic patients with cardiovascular dysautonomy
Type 2 diabetic patients with more severe CAN have higher SBP and PP, especially during the nighttime and early morning, as well as a higher prevalence of nondipping status (PubMed)
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes
A randomised, open-label, non-inferiority study (The Lancet, UK)
Dr Reddy’s diabetes drug may be delayed
Rheoscience A/S, the Danish firm conducting phase III clinical trials on Balaglitazone, has run into a financial crisis (Live Mint. Wall Street Journal, USA)
Is diabetes education truly profitable?
Yes, but educators must explore other money-making opportunities – Yes, but educators must think like a business, act like a business (Endocrine Today, USA)
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