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Diabetes News

Category: Monitoring


Elevation of plasma advanced oxidation protein products early marker T2D

February 11th 2014

Elevation of plasma advanced oxidized protein products was an independent risk factor for endothelial dysfunction, and therefore, might be an early marker of vasculopathy in individuals with early stage of diabetes (Journal of Diabetes)

Categories: Monitoring, News

Categories: Monitoring

High plasma estradiol interacts with diabetes on risk of dementia in older postmenopausal women

February 10th 2014

High E2 level is an independent predictor of incident dementia, particularly in postmenopausal women with diabetes (Neurology)

Categories: Monitoring, News

Categories: Monitoring

Modeling of 24-Hour Glucose and Insulin Profiles T2D Treated With Biphasic Insulin Aspart

January 27th 2014

Circadian variations in glucose homeostasis were assessed on relevant parameters, and a significant improvement was achieved by including a circadian rhythm on the endogenous glucose production in the model. The extended model is a useful tool for clinical trial simulation and for elucidating the effect profile of new insulin products (Journal of Clinical Pharmacology)

Categories: Monitoring, News

Categories: Monitoring

Quantitative Estimation Insulin Sensitivity T1D & Sensor Augmented Pump

December 9th 2013

This new index correlates well with the reference oral minimal model estimate of insulin sensitivity. The knowledge of patient-specific insulin sensitivity and its diurnal variation can help in optimizing insulin therapy in type 1 diabetes and could also inform the next generation closed-loop control systems (Diabetes Care)

Categories: Monitoring, News

Categories: Monitoring

Non-invasive detection of microvascular changes – paediatric T1D

October 18th 2013

This pilot study has shown that in children and adolescents with established type 1 diabetes, abnormal microvasculature can be detected by nailfold capillaroscopy, laser Doppler flowmetry, retinal vessel analysis and 24-hr ambulatory blood pressure monitoring (BMC Endocrine Disorders)

Categories: Monitoring, News

Categories: Monitoring

Ethnic Differences in Glycemic Markers in T2D

October 12th 2013

For a given degree of glycemia, HbA1c levels vary among different ethnic groups. Ethnicity needs to be taken into account when using HbA1c to assess glycemic control or to set glycemic targets. Estimated AG is not a reliable marker for mean glycemia and therefore is of limited clinical value (Diabetes Care)

Categories: Monitoring, News

Categories: Monitoring

Psychosocial risk index for poor glycemic control – children T1D

October 1st 2013

This paper presents the first psychosocial risk index for poor glycemic control in children newly diagnosed with type 1 diabetes. It is brief, easily administered, and provides a single score that translates directly into an estimate of risk that can help guide routine diabetes care (Pediatric Diabetes)

Categories: Monitoring, News

Categories: Monitoring

Time Lag of Glucose from Intravascular to Interstitial Compartment

September 17th 2013

Physiological delay between blood glucose and interstitial fluid glucose should, therefore, not be an obstacle to sensor accuracy in overnight or fasting state closed loop systems of insulin delivery or open loop therapy assessment for type 1 diabetes (Diabetes)

Categories: Monitoring, News

Categories: Monitoring

Do we need continuous glucose monitoring in T2D?

August 26th 2013

Although the studies on the economic feasibility to use CGM as an educational tool must be carried out, we suggest that it can be used as a powerful motivational device to change patients’ lifestyle and to improve glycaemic control in type 2 diabetes (Diabetes/Metabolism Research and Reviews)

Categories: Monitoring, News

Categories: Monitoring

Diabetes Medicines Use Review (MUR) Toolkit

August 3rd 2013

This ‘Diabetes MUR toolkit’ is designed to help improve the confidence of community pharmacy to provide high quality MURs for patients taking diabetes medicines (Devon Local Pharmaceutical Committee)

Categories: Monitoring, News

Categories: Monitoring

HbA1c and Risk of Severe Hypoglycemia in T2D

July 31st 2013

Severe hypoglycemia was common among patients with type 2 diabetes across all levels of glycemic control. Risk tended to be higher in patients with either near-normal glycemia or very poor glycemic control (Diabetes Care)

Categories: Monitoring, News

Categories: Monitoring

Biomarkers T2D – non-targeted metabolomics approach

July 26th 2013

this T2D-IFG biomarker study has surveyed the broadest panel of non-targeted metabolites to date, revealing both novel and known associated metabolites and providing potential novel targets for clinical prediction and a deeper understanding of causal mechanisms (Diabetes)

Categories: Monitoring, News

Categories: Monitoring

Abbott Receives FDA Clearance for FreeStyle Precision Pro

July 25th 2013

Only inpatient blood glucose monitoring system among leading hospital brands to use individually foil-wrapped test strips, helping reduce risk of test strip cross-contamination (Abbott)

Categories: Monitoring, News

Categories: Monitoring

Postprandial serum C-peptide – glucose ratio correlates OGT

July 15th 2013

F-CPI was correlated only with unadjusted indexes of insulin secretion, whereas PP-CPI was correlated with such indexes as well as with those adjusted for insulin sensitivity. The better clinical utility of PP-CPI might be attributable to these physiological characteristics (Metabolism)

Categories: Monitoring, News

Categories: Monitoring

Recent HbA1c & Mortality Risk T2D

July 12th 2013

The present findings suggest that an HbA1c target of less than 6.5% or 48 mmol/mol might be too low for some patients and large reductions, or increases, in HbA1c levels should be approached cautiously. The findings also point to potential age-related differences in HbA1c levels and mortality rates with younger diabetes patients being at relatively greater risk of mortality associated with low HbA1c levels even though absolute risks are smaller at young ages (PLoS ONE)

Categories: Monitoring, News

Categories: Monitoring

Urinary C-peptide creatinine ratio detects absolute insulin deficiency T2D

May 14th 2013

The urinary C-peptide creatinine ratio is a practical non-invasive method to aid detection of absolute insulin deficiency, with a urinary C-peptide creatinine ratio > 0.2nmol/mmol being a reliable indicator of retained endogenous insulin secretion (Diabetic Medicine)

Categories: Monitoring, News

Categories: Monitoring

Correlation HDL & beta-cell function re: glucose tolerance

April 30th 2013

In subjects with impaired glucose regulation, HDL-C levels are associated with indices of beta-cell dysfunction; thus, more attention, it should be deserve to HDL-C concentrations in IFG/IGT patients due their potential conversion to DM2 (Acta Diabetologica)

Categories: Monitoring, News

Categories: Monitoring

Self-monitoring among non-insulin treated patients with T2D

April 9th 2013

Responding to SMBG test results and increased testing frequency were not associated with improved glycaemic control in the short-term. There is a lack of knowledge surrounding SMBG in non-insulin treated patients (Diabetes Research and Clinical Practice)

Categories: Monitoring, News

Categories: Monitoring

Slow-Twitch Fiber Proportion Correlates with Insulin Responsiveness

March 26th 2013

Lower proportion of type I fibers in metabolic syndrome muscle correlated with the severity of insulin resistance. Even though whole muscle content was normal, key elements of insulin action were consistently less in type I muscle fibers, suggesting their distribution was important in mediating insulin effects (Journal of Clinical Endocrinology & Metabolism)

Categories: Monitoring, News

Categories: Monitoring

Altered immune profile from pre-diabetes to manifestation of T1D

March 7th 2013

Changes in immunity seen in individuals with high risk of developing T1D points to alterations/actions in the immune system already early in the pre-diabetic phase (Diabetes Research and Clinical Practice)

Categories: Monitoring, News

Categories: Monitoring
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