Improved glucose control over a 2-year follow-up was associated with a more favorable lipid profile but may be insufficient to normalize lipids in dyslipidemic T1D youth needing to decrease lipids to goal (The Journal of Pediatrics)
Diabetes News
Glycosmedia is dedicated to bringing free, non-promotional, editorially independent news to a global audience about developments in diabetes, and is primarily aimed at health professionals.
Pancreatic exocrine function in patients with diabetes
Factors associated with pancreatic exocrine failure differ in patients with Type 1 diabetes compared with patients with type 2 diabetes. In patients with Type 2 diabetes, association of decreased pancreatic exocrine function with BMI and vascular disease suggests a role of pancreatic arteriopathy (Diabetic Medicine)
CTX (Crosslaps) Rather than Osteopontin Is Associated with Disturbed Glucose Metabolism in Gestational Diabetes
Our findings support the idea of a tight regulation between bone and glucose metabolism, and suggest, that less curbed CTX during pregnancy might be involved in osteocalcin-mediated amelioration of insulin secretion in GDM (PLoS ONE)
A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
The data present a global map of genes associated with islet dysfunction and demonstrate the value of systems genetics for the identification of genes potentially involved in T2D (Cell Metabolism)
An Invasive or Conservative Strategy in Patients With Diabetes Mellitus and Non–ST-Segment Elevation Acute Coronary Syndromes
An early invasive strategy yielded similar RR reductions in overall cardiovascular events in diabetic and nondiabetic patients. However, an invasive strategy appeared to reduce recurrent nonfatal MI to a greater extent in diabetic patients (Journal of the American College of Cardiology)
Glycosylated hemoglobin (HbA1c) levels and clinical outcomes in diabetic patients following coronary artery stenting
Our data suggest that there is an association between good glycaemic control to obtain HbA1c levels (both pre-procedural glycaemic control and post-procedural) with a better clinical outcome after PCI (Cardiovascular Diabetology)
Predictors of Deteriorations in Diabetes Management and Control in Adolescents With Type 1 Diabetes
Demographic and medical factors may call for proactive efforts to prevent deterioration, and psychological symptoms and family conflict signal opportunities for clinical intervention to promote improved diabetes management and control in adolescence (Journal of Adolescent Heath)
Insulin resistance is a big risk factor for the progression of liver fibrosis in HIV/HCV co-infected people
The presence of insulin resistance is associated with poorer responses to hepatitis C therapy in mono-infected patients. However, it is unclear if the progression of insulin resistance is associated with the progression of liver fibrosis in co-infected patients (Aidsmap)
Gestational Diabetes Reduces Adenosine Transport in Human Placental Microvascular Endothelium, an Effect Reversed by Insulin
This could explain the elevated umbilical vein blood adenosine concentration detected in GDM (PL0S ONE)
Preventing type 2 diabetes
Risk identification and interventions for individuals at high risk (NICE)
Diabetes: Exploring a periodontal connection
Periodontitis is more prevalent among persons with DM, the poor, and the elderly. In fact, periodontal disease has been called the sixth complication of DM (JAAPA)
Umbilical Artery Intima-Media and Wall Thickness in Infants of Diabetic Mothers
Measurement of umbilical artery wall thickness in the third trimester is feasible, reproducible and strongly correlated with pathological serum insulin, C-peptide in cord blood and HOMA-IR levels (Neonatology)
Evaluation of a DVD for women with diabetes: impact on knowledge and attitudes to preconception care
This study demonstrates the effectiveness of a DVD in increasing knowledge and enhancing attitudes of women with diabetes to preconception care. This DVD could be used as a prepregnancy counselling resource to prepare women with diabetes for pregnancy (Diabetic Medicine)
Adiponectin and All-Cause Mortality in Elderly People With Type 2 Diabetes
Contrary to our hypothesis, higher adiponectin level was related to higher all-cause mortality. This association was not explained by confounding by other characteristics, including medications or preceding weight loss (Diabetes Care)
Abbott Announces New Test for the Management of Patients with Diabetes
The new fully-automated assay measures glycated hemoglobin (HbA1c), the recommended test to monitor diabetic patients in the laboratory (Abbott)
The Relationship Between Glycosylated Hemoglobin and Myocardial Perfusion Imaging
This study shows a significantly higher risk of abnormal MPI and CAD in diabetic patients with suboptimal and poor long-term glycemic control, further emphasizing the need for aggressive risk factor modification to minimize vascular complications from DM (Clinical Cardiology)
Birth-weight, insulin levels, and HOMA-IR in newborns at term
Our results suggest that LGA is associated with hyperinsulinemia and elevated HOMA-IR at birth whereas the SGA show a tendency of association (BMC Pediatrics)
Revealed: DH plans to bundle diabetes QOF indicators worth over £5,000
GPs will be forced to conduct nine separate checks in each patient with diabetes under Department of Health plans to create a single diabetes QOF indicator worth over £5,000 (Pulse)
High levels of lipoprotein(a) are associated with a lower prevalence of diabetes with advancing age
Results of a cross-sectional epidemiological survey in Gran Canaria, Spain (Cardiovascular Diabetology)
Gestational diabetes screening with the new IADPSG guidelines: a cost-effectiveness analysis
Screening at 24-28 weeks GA under the new IADPSG guidelines with the 2h GTT is expensive but cost-effective in improving maternal and neonatal outcomes (American Journal of Obstetrics & Gynecology)
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